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The map label for this gene is xylH [H]

Identifier: 218691856

GI number: 218691856

Start: 4174943

End: 4176124

Strand: Direct

Name: xylH [H]

Synonym: ECED1_4254

Alternate gene names: 218691856

Gene position: 4174943-4176124 (Clockwise)

Preceding gene: 218691855

Following gene: 218691857

Centisome position: 80.14

GC content: 53.89

Gene sequence:

>1182_bases
ATGTCGAAAAGCAATCCGTCTGAAGTGAAATTAGCCGTACCGACATCCGGTGGCCTTTCCGGGCTGAAATCACTGAATTT
GCAGGTCTTCGTGATGATTGCAGCTATCATCGCAATCATGCTGTTCTTTACCTGGACCACCGATGGTGCCTACTTAAGCG
CCCGTAACGTCTCCAACCTGTTACGCCAAACCGCGATTACCGGCATCCTCGCGGTAGGAATGGTGTTCGTCATAATTTCT
GCTGAAATCGACCTTTCCGTCGGCTCAATGATGGGGCTGTTAGGTGGCGTCGCGGCGATTTGTGACGTCTGGCTAGGCTG
GCCTTTGCCACTTACCATCATTGTGACGTTGGTTCTGGGACTGCTTCTCGGAGCCTGGAACGGATGGTGGGTCGCGTACC
GCAAAGTCCCTTCATTTATTGTCACCCTCGCAGGCATGTTGGCATTTCGTGGCATACTCATTGGCATCACCAACGGCACG
ACTGTTTCCCCCACCAGCGCCGCGATGTCACAAATTGGGCAAAGCTATCTACCTGCCAGCACCGGCTTCATCATTGGCGC
GCTTGGCTTAATGGCTTTTGTTGGCTGGCAATGGCGCGGAAGAATGCGCCGTCAGGCTTTGGGTTTGCAGTCTCCGGCCT
CTACCGCAGTAGTCGGTCGCCAGGCTTTAACCGCTATCATCGTATTAGGCGCAATCTGGCTGTTGAATGATTACCGTGGT
GTTCCCACTCCTGTTCTGCTGCTGACGTTGCTGTTACTCGGCGGAATGTTTATGGCAACGCGGACGGCATTTGGACGACG
CATTTATGCCATCGGCGGCAATCTGGAAGCGGCACGTCTCTCCGGGATTAACGTTGAACGCACCAAACTTGCCGTGTTCG
CTATTAACGGATTAATGGTAGCCATCGCCGGATTAATCCTCAGTTCTCGACTCGGCGCTGGTTCACCTTCTGCGGGAAAT
ATCGCCGAACTGGACGCAATTGCAGCATGTGTGATTGGCGGCACCAGTCTGGCAGGCGGCGTCGGGAGCGTGGCTGGAGC
AGTAATGGGGGCATTCATCATGGCTTCACTGGATAACGGCATGAGTATGATGGATGTACCGACCTTCTGGCAGTATATCG
TTAAAGGTGCGATTCTGTTGCTGGCAGTATGGATGGACTCCGCAACCAAACGCCGTTCTTGA

Upstream 100 bases:

>100_bases
CGTGTACTGGTGATGCATGAAGGGAAACTAAAAGCCAACCTGATAAATCATAACCTGACTCAGGAGCAGGTGATGGAAGC
CGCATTGAGGAGCGAACATC

Downstream 100 bases:

>100_bases
TTTTGATAAAAATTCTCTCAAAGCCGGTAACGTATTACCGGTTTTGAGTTTTTGCATGATTCAGCAGGAAAAGAACCATG
TTTACTAAACGTCACCGCAT

Product: D-xylose ABC transporter membrane protein

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSKSNPSEVKLAVPTSGGLSGLKSLNLQVFVMIAAIIAIMLFFTWTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIIS
AEIDLSVGSMMGLLGGVAAICDVWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVVGRQALTAIIVLGAIWLLNDYRG
VPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGN
IAELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRRS

Sequences:

>Translated_393_residues
MSKSNPSEVKLAVPTSGGLSGLKSLNLQVFVMIAAIIAIMLFFTWTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIIS
AEIDLSVGSMMGLLGGVAAICDVWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVVGRQALTAIIVLGAIWLLNDYRG
VPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGN
IAELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRRS
>Mature_392_residues
SKSNPSEVKLAVPTSGGLSGLKSLNLQVFVMIAAIIAIMLFFTWTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIISA
EIDLSVGSMMGLLGGVAAICDVWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGTT
VSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVVGRQALTAIIVLGAIWLLNDYRGV
PTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGNI
AELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRRS

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=393, Percent_Identity=99.7455470737914, Blast_Score=756, Evalue=0.0,
Organism=Escherichia coli, GI1790191, Length=359, Percent_Identity=35.933147632312, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1788896, Length=161, Percent_Identity=39.7515527950311, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI145693152, Length=341, Percent_Identity=31.3782991202346, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87082395, Length=342, Percent_Identity=30.7017543859649, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787793, Length=345, Percent_Identity=31.0144927536232, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1790524, Length=152, Percent_Identity=39.4736842105263, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788471, Length=376, Percent_Identity=30.8510638297872, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI145693214, Length=311, Percent_Identity=31.5112540192926, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787794, Length=157, Percent_Identity=31.2101910828025, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 40998; Mature: 40866

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKSNPSEVKLAVPTSGGLSGLKSLNLQVFVMIAAIIAIMLFFTWTTDGAYLSARNVSNL
CCCCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHH
LRQTAITGILAVGMVFVIISAEIDLSVGSMMGLLGGVAAICDVWLGWPLPLTIIVTLVLG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGTTVSPTSAAMSQIGQSYLPAS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHCHHHCCCC
TGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVVGRQALTAIIVLGAIWLLNDYRG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMV
CCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCCCCHHEEEEHHHHHHHH
AIAGLILSSRLGAGSPSAGNIAELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHCCC
MSMMDVPTFWQYIVKGAILLLAVWMDSATKRRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]