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The map label for this gene is nupG [H]

Identifier: 218691088

GI number: 218691088

Start: 3370155

End: 3371411

Strand: Direct

Name: nupG [H]

Synonym: ECED1_3427

Alternate gene names: 218691088

Gene position: 3370155-3371411 (Clockwise)

Preceding gene: 218691087

Following gene: 218691090

Centisome position: 64.69

GC content: 50.68

Gene sequence:

>1257_bases
ATGAATCTTAAGCTGCAGCTGAAAATCCTCTCTTTTCTGCAGTTCTGTCTATGGGGAAGTTGGCTGACGACCCTCGGCTC
CTATATGTTTGTTACCCTGAAGTTTGACGGTGCTTCTATCGGCGCAGTTTATAGCTCACTGGGTATCGCCGCGGTCTTTA
TGCCTGCGCTGCTGGGGATTGTGGCCGACAAATGGTTAAGTGCGAAATGGGTCTATGCCATTTGCCACACCATTGGCGCT
ATCACGCTGTTCATGGCGGCAGAGGTCACTACGCCGGAGGCGATGTTCCTTGTGATATTGATTAACTCGTTTGCTTATAT
GCCAACGCTTGGGTTAATCAACACCATCTCTTACTATCGCCTGCAAAATGCCGGGATGGATATCGTTACTGACTTCCCGC
CAATCCGTATCTGGGGCACCATCGGCTTTATCATGGCAATGTGGGTGGTGAGCCTGTCCGGCTTCGAATTAAGCCACATG
CAGCTGTATATTGGCGCAGCGCTTTCCGCCATTCTGGTTCTGTTTACCCTGACTCTGCCGCATATTCCGGTTGCTAAACA
GCAAGCGAATCAGAGCTGGACAACCCTGCTGGGCCTCGATGCATTCGCGCTGTTTAAAAACAAGCGTATGGCAATCTTCT
TCATCTTCTCAATGCTGCTGGGCGCGGAACTGCAGATTACCAACATGTTCGGTAATACCTTCCTGCACAGCTTCGACAAA
GATCCGATGTTTGCCAGCAGCTTCATCGTGCAGCATGCGTCAATCATCATGTCGATTTCGCAGATCTCTGAAACCCTGTT
CATTCTGACCATCCCGTTCTTCTTAAGCCGCTACGGTATTAAGAACGTAATGATGATCAGTATTGTGGCGTGGATCCTGC
GTTTTGCTCTGTTTGCTTACGGCGACCCGACTCCGTTCGGTACTGTACTGCTGGTACTGTCGATGATCGTTTACGGTTGC
GCATTCGACTTCTTCAACATCTCTGGTTCGGTGTTTGTCGAAAAAGAAGTTAGCCCGGCAATTCGCGCCAGCGCGCAGGG
GATGTTCCTGATGATGACCAACGGCTTCGGCTGTATCCTCGGCGGCATCGTGAGCGGTAAAGTGGTTGAGATGTACACCC
AAAACGGCATTACCGACTGGCAGACCGTATGGCTGATTTTCGCAGGTTACTCCGTGGTTCTGGCCTTCGCGTTCATGGCG
ATGTTCAAATATAAACACGTTCGTGTCCCGACAGGTACACAGACGGTTAGCCACTAA

Upstream 100 bases:

>100_bases
ACAAAAAACCAGTCCGCGAAGTTGATAGAATCGCATCATCTCGCACGGTCAAATGTGCTTTTTCAAACACTCATCCGCAT
CACGATGTGAGGAAATTAAC

Downstream 100 bases:

>100_bases
TTACGCAAAGAAAAACGGGTCGCCAGAAGGTGACCCGTTTTTTTATTCTTACTTCAACACATAACCGTACAACCGTTTCA
TGCCATCCGCATCGGTTTCG

Product: nucleoside transporter

Products: NA

Alternate protein names: Nucleoside-transport system protein nupG [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVYSSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGA
ITLFMAAEVTTPEAMFLVILINSFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
QLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAELQITNMFGNTFLHSFDK
DPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGC
AFDFFNISGSVFVEKEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSVVLAFAFMA
MFKYKHVRVPTGTQTVSH

Sequences:

>Translated_418_residues
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVYSSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGA
ITLFMAAEVTTPEAMFLVILINSFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
QLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAELQITNMFGNTFLHSFDK
DPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGC
AFDFFNISGSVFVEKEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSVVLAFAFMA
MFKYKHVRVPTGTQTVSH
>Mature_418_residues
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVYSSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGA
ITLFMAAEVTTPEAMFLVILINSFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
QLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAELQITNMFGNTFLHSFDK
DPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGC
AFDFFNISGSVFVEKEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSVVLAFAFMA
MFKYKHVRVPTGTQTVSH

Specific function: Transports nucleosides with a high affinity. Driven by a proton motive force [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli xapB and yegT [H]

Homologues:

Organism=Escherichia coli, GI87082192, Length=418, Percent_Identity=99.7607655502392, Blast_Score=842, Evalue=0.0,
Organism=Escherichia coli, GI1788745, Length=418, Percent_Identity=58.3732057416268, Blast_Score=477, Evalue=1e-136,
Organism=Escherichia coli, GI1788415, Length=417, Percent_Identity=30.2158273381295, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR004740 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46391; Mature: 46391

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVYSSLGIAAVFMPALLGI
CCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
VADKWLSAKWVYAICHTIGAITLFMAAEVTTPEAMFLVILINSFAYMPTLGLINTISYYR
HHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHMQLYIGAALSAILVLFTLTLP
HHCCCCCEEECCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
HIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAELQITNMFGNTFLHSFDK
CCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCC
DPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVMMISIVAWILRFALFAY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
GDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVEKEVSPAIRASAQGMFLMMTNGFGCIL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHCCCCEEEEEECCCHHHH
GGIVSGKVVEMYTQNGITDWQTVWLIFAGYSVVLAFAFMAMFKYKHVRVPTGTQTVSH
HHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCC
>Mature Secondary Structure
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVYSSLGIAAVFMPALLGI
CCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
VADKWLSAKWVYAICHTIGAITLFMAAEVTTPEAMFLVILINSFAYMPTLGLINTISYYR
HHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHMQLYIGAALSAILVLFTLTLP
HHCCCCCEEECCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
HIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAELQITNMFGNTFLHSFDK
CCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCC
DPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVMMISIVAWILRFALFAY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
GDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVEKEVSPAIRASAQGMFLMMTNGFGCIL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHCCCCEEEEEECCCHHHH
GGIVSGKVVEMYTQNGITDWQTVWLIFAGYSVVLAFAFMAMFKYKHVRVPTGTQTVSH
HHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3311747; 9278503 [H]