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The map label for this gene is fadL [H]

Identifier: 218690503

GI number: 218690503

Start: 2747798

End: 2749144

Strand: Direct

Name: fadL [H]

Synonym: ECED1_2807

Alternate gene names: 218690503

Gene position: 2747798-2749144 (Clockwise)

Preceding gene: 218690491

Following gene: 218690506

Centisome position: 52.75

GC content: 47.14

Gene sequence:

>1347_bases
ATGGTCATGAGCCAGAAAACCCTGTTTACAAAGTCTGCTCTCGCAGTCGCAGTGGCACTTATCTCCACCCAGGCCTGGTC
GGCAGGCTTTCAGTTAAACGAATTTTCTTCCTCTGGCCTGGGCCGGGCTTATTCAGGGGAAGGTGCAATTGCCGATGATG
CAGGTAACGTTAGCCGTAACCCCGCATTGATTACCATGTTTGACCGCCCGACATTTTCTGCGGGTGCGGTTTATATTGAT
CCGGATGTAGATATTACCGGACATTCTGATTTAACCGGTCAGAGTGCAAATGCTAAAAATATCGCACCGACAGCATGGGT
ACCTAACCTGCACTTTGTTGCGCCTATTAACGATCAGTTTGGTTGGGGAGCGTCAATAACTTCCAACTATGGCCTGGCTA
CGGAATTTACCGACAACTACGCTGCTGGTATCTATGGCGGTAAAACCGATCTGCAAACAATCAACCTTAACCTTAGCGGG
GCTTATCGCCTTAACAATAGCTGGAGTTTTGGTCTTGGTTTTGATGCAGTTTATGCCAAGGCAAAAATTGAGCGTTACGC
CGGTTCGCTGGGGCCATTGTTGTCTCAACAGTTGATTGCCCAGGGTGTACCCGCTTCATTAACCAATGGTATTAATACTC
CGGACTCTCAAATTGCTCATTTGAAAGGTGACGAATGGGGCTTTGGCTGGAACGCGGGTATTCTTTATGAACTGGATAAA
GATAACCGTTGGGGGCTGACATATCGTTCAGAAGTTAAAATCGACTTCGATGGGGATTACAAAAGCTCCATTAACCCAAA
TCTGAACAATATTTTGGGTAACATGGGCTTACCGTATGGCACGATGGGGGCAACCCAAAATGGATCCTTAACGCTGAACC
TACCTGAGATGTGGGAGATTTCTGGTTATAACCGTGTTGCACCGCAGTGGGCAATTCACTACAGCATGGCCTATACCAGT
TGGAGCCAGTTCCAGGAATTGAAAGCGAAAGGCGATAGTGGTCAGACTCTGTTCTATAAAGATGAAGGATTCCGGGACGC
GTATCGTATCGCGTTGGGTACAACCTACTATTATGATAAAAACTGGACCTTCCGTACCGGTATCGCTTATGACGACAGCC
CGGTTCCGGCAGATAAACGTTCTATTTCCATTCCTGACCAGGATCGTTTGTGGTTAAGTGCTGGGTTAACCTACGCATTT
AATGAAGATGCATCCATTGATGTTGGCGCATCTTATATGCATGGTCAGAAAGTGAAATTCACCGAAGGTGAAGGAGCGGC
AGCTTATTCCTTCGAGTCTGAAGGTAAAGCCTGGCTGTTCGGTACTAACTTTAACTACGCGTTCTGA

Upstream 100 bases:

>100_bases
TCGCCACTGGTCTGATTTCTAAGATGTACCTCAGACCCTACACTTCGCGCTCCTGTTACAGCACGTAACATAGTTTGTAT
AAAAATAAATCATTGAGGTT

Downstream 100 bases:

>100_bases
TAACGCGTTAGCTTAATAAGAAAAAAGGTGAGTTTTGCGACTCACCTTTTTTGTTTGTTTCTTATTCAGAATCGATATCT
TTTAAATCATCCTGAATCGC

Product: long-chain fatty acid outer membrane transporter

Products: NA

Alternate protein names: Outer membrane fadL protein; Outer membrane flp protein [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MVMSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSGEGAIADDAGNVSRNPALITMFDRPTFSAGAVYID
PDVDITGHSDLTGQSANAKNIAPTAWVPNLHFVAPINDQFGWGASITSNYGLATEFTDNYAAGIYGGKTDLQTINLNLSG
AYRLNNSWSFGLGFDAVYAKAKIERYAGSLGPLLSQQLIAQGVPASLTNGINTPDSQIAHLKGDEWGFGWNAGILYELDK
DNRWGLTYRSEVKIDFDGDYKSSINPNLNNILGNMGLPYGTMGATQNGSLTLNLPEMWEISGYNRVAPQWAIHYSMAYTS
WSQFQELKAKGDSGQTLFYKDEGFRDAYRIALGTTYYYDKNWTFRTGIAYDDSPVPADKRSISIPDQDRLWLSAGLTYAF
NEDASIDVGASYMHGQKVKFTEGEGAAAYSFESEGKAWLFGTNFNYAF

Sequences:

>Translated_448_residues
MVMSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSGEGAIADDAGNVSRNPALITMFDRPTFSAGAVYID
PDVDITGHSDLTGQSANAKNIAPTAWVPNLHFVAPINDQFGWGASITSNYGLATEFTDNYAAGIYGGKTDLQTINLNLSG
AYRLNNSWSFGLGFDAVYAKAKIERYAGSLGPLLSQQLIAQGVPASLTNGINTPDSQIAHLKGDEWGFGWNAGILYELDK
DNRWGLTYRSEVKIDFDGDYKSSINPNLNNILGNMGLPYGTMGATQNGSLTLNLPEMWEISGYNRVAPQWAIHYSMAYTS
WSQFQELKAKGDSGQTLFYKDEGFRDAYRIALGTTYYYDKNWTFRTGIAYDDSPVPADKRSISIPDQDRLWLSAGLTYAF
NEDASIDVGASYMHGQKVKFTEGEGAAAYSFESEGKAWLFGTNFNYAF
>Mature_448_residues
MVMSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSGEGAIADDAGNVSRNPALITMFDRPTFSAGAVYID
PDVDITGHSDLTGQSANAKNIAPTAWVPNLHFVAPINDQFGWGASITSNYGLATEFTDNYAAGIYGGKTDLQTINLNLSG
AYRLNNSWSFGLGFDAVYAKAKIERYAGSLGPLLSQQLIAQGVPASLTNGINTPDSQIAHLKGDEWGFGWNAGILYELDK
DNRWGLTYRSEVKIDFDGDYKSSINPNLNNILGNMGLPYGTMGATQNGSLTLNLPEMWEISGYNRVAPQWAIHYSMAYTS
WSQFQELKAKGDSGQTLFYKDEGFRDAYRIALGTTYYYDKNWTFRTGIAYDDSPVPADKRSISIPDQDRLWLSAGLTYAF
NEDASIDVGASYMHGQKVKFTEGEGAAAYSFESEGKAWLFGTNFNYAF

Specific function: Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel [H]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family [H]

Homologues:

Organism=Escherichia coli, GI145693163, Length=454, Percent_Identity=76.8722466960352, Blast_Score=692, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR005017 [H]

Pfam domain/function: PF03349 Toluene_X [H]

EC number: NA

Molecular weight: Translated: 48911; Mature: 48911

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSGEGAIADDAGNVSRN
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEECCCCCEECCCCCCCCC
PALITMFDRPTFSAGAVYIDPDVDITGHSDLTGQSANAKNIAPTAWVPNLHFVAPINDQF
CEEEEEECCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCEECCCEEEEEECCCCC
GWGASITSNYGLATEFTDNYAAGIYGGKTDLQTINLNLSGAYRLNNSWSFGLGFDAVYAK
CCCCEECCCCCEEEECCCCCEEEEECCCCCEEEEEEEEEEEEEECCCEEECCCHHHHHHH
AKIERYAGSLGPLLSQQLIAQGVPASLTNGINTPDSQIAHLKGDEWGFGWNAGILYELDK
HHHHHHHCHHHHHHHHHHHHCCCCHHHHCCCCCCCHHEEEECCCCCCCCCCCCEEEEECC
DNRWGLTYRSEVKIDFDGDYKSSINPNLNNILGNMGLPYGTMGATQNGSLTLNLPEMWEI
CCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEE
SGYNRVAPQWAIHYSMAYTSWSQFQELKAKGDSGQTLFYKDEGFRDAYRIALGTTYYYDK
CCCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEEEEEECC
NWTFRTGIAYDDSPVPADKRSISIPDQDRLWLSAGLTYAFNEDASIDVGASYMHGQKVKF
CCEEEECCEECCCCCCCCCCEECCCCCCCEEEEECEEEEECCCCCEECCCHHHCCCEEEE
TEGEGAAAYSFESEGKAWLFGTNFNYAF
ECCCCCEEEEECCCCCEEEEECCCCCCC
>Mature Secondary Structure
MVMSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSGEGAIADDAGNVSRN
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEECCCCCEECCCCCCCCC
PALITMFDRPTFSAGAVYIDPDVDITGHSDLTGQSANAKNIAPTAWVPNLHFVAPINDQF
CEEEEEECCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCEECCCEEEEEECCCCC
GWGASITSNYGLATEFTDNYAAGIYGGKTDLQTINLNLSGAYRLNNSWSFGLGFDAVYAK
CCCCEECCCCCEEEECCCCCEEEEECCCCCEEEEEEEEEEEEEECCCEEECCCHHHHHHH
AKIERYAGSLGPLLSQQLIAQGVPASLTNGINTPDSQIAHLKGDEWGFGWNAGILYELDK
HHHHHHHCHHHHHHHHHHHHCCCCHHHHCCCCCCCHHEEEECCCCCCCCCCCCEEEEECC
DNRWGLTYRSEVKIDFDGDYKSSINPNLNNILGNMGLPYGTMGATQNGSLTLNLPEMWEI
CCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEE
SGYNRVAPQWAIHYSMAYTSWSQFQELKAKGDSGQTLFYKDEGFRDAYRIALGTTYYYDK
CCCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEEEEEECC
NWTFRTGIAYDDSPVPADKRSISIPDQDRLWLSAGLTYAFNEDASIDVGASYMHGQKVKF
CCEEEECCEECCCCCCCCCCEECCCCCCCEEEEECEEEEECCCCCEECCCHHHCCCEEEE
TEGEGAAAYSFESEGKAWLFGTNFNYAF
ECCCCCEEEEECCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]