Click here to switch to the map view.

The map label for this gene is baeS [H]

Identifier: 218690136

GI number: 218690136

Start: 2371901

End: 2373304

Strand: Direct

Name: baeS [H]

Synonym: ECED1_2424

Alternate gene names: 218690136

Gene position: 2371901-2373304 (Clockwise)

Preceding gene: 218690135

Following gene: 218690137

Centisome position: 45.53

GC content: 53.13

Gene sequence:

>1404_bases
ATGAAGTTCTGGCGACCCGGTATTACCGGCAAACTGTTTCTGGCGATTTTCGCCACCTGCATTGTCTTATTGATCACGAT
GCACTGGGCGGTACGTATCAGTTTTGAGCGCGGCTTTATCGATTACATCAAGCATGGTAATGAACAACGGCTGCAAATGC
TCGGCGATGCGCTTGGTGAGCAGTACGCCCAGCACGGGAACTGGCGCTTCCTGCGTAATAACGATCGCTTTGTATTTCAG
ATCCTACGTTCACTGGAGCATGATAACAACGAAGATAAGCCCGGCCCCGGTATGCCACCACACGGCTGGCGCACGCAATT
TTGGGTGGTTGATCAAAATAATAAAGTGCTGGTTGGCCCGCGAGCACCGGTTCCACCCGACGGCACACGGCGGCCCATTA
TGGTCAATGGTGCGGAAGTTGGCGCGGTGATCGCCTCCCCTGTTGAACGACTGACCCGTAATACTGATATCAATTTTGAC
AGACAACAGCGGCAAACCAGTTGGCTGATTGTGGCTTTATCTACCTTATTAGCGGCGCTGGCGACATTCCCACTGGCGCG
CGGTTTGCTGGCTCCGGTAAAACGACTGGTGGATGGCACGCACAAACTGGCAGCGGGTGATTTCACTACTCGCGTAGCCC
CCACCAGCGAAGATGAGTTGGGCAGACTGGCAGAGGATTTCAATCAACTCGCCAGCACACTGGAGAAAAACCAGCAGATG
CGCCGCGATTTTATGGCCGATATTTCTCATGAACTGCGCACGCCTTTAGCAGTACTGCGCGGCGAACTGGAAGCCATTCA
GGATGGTGTGCGTAAATTCACGCCGGAGACGCTGGCTTCTTTACAGGCAGAAGTCGGAACACTGACAAAACTGGTTGACG
ATCTCCATCAATTGTCTATGTCTGATGAAGGCGCTCTCGCCTATCAAAAAGCACCGGTAGATTTGATCCCACTGCTGGAA
GTGGCGGGAGGCGCATTTCGCGAACGATTCGCCAGCCGTGGCCTGAAATTGCAATTTTCCCTGCCAGACAGTATTACCGT
ATTTGGCGATCGCGATCGTTTAATGCAGTTGTTCAATAACTTACTGGAAAACAGCCTGCGCTACACTGACAGCGGCGGCA
GCCTGAAAATCTCTGCCGAACAGCACGACAAAACGGTGCGCCTGACCTTTGCCGACAGTGCGCCGGGTGTCAGTGACGAT
CAGCTACAAAAATTGTTTGAACGTTTTTATCGCACCGAAGGTTCCCGCAACCGCGCCAGCGGTGGTTCCGGGCTGGGGCT
GGCGATTTGCCTGAACATTGTTGAAGCACATAACGGCCGCATTATTGCCGCCCATTCGCCTTTTGGCGGGCTTAGCATTA
CAGTAGAGTTACCGCTGGAACGGGATTTACAGAGAGAAGTATGA

Upstream 100 bases:

>100_bases
GCATGGCGTTTATCATCGCCCTTCCGGCGTTTGTCTTTGCCAGAGTGCCGAGCGATACGCATCAAAATGTGGCTATTTCA
CGGCGAAAAAGGAGCGCGCA

Downstream 100 bases:

>100_bases
CCGAGTTACCAATCGACGAAAACACACCGCGTATTTTGATCGTGGAAGATGAACCGAAGCTGGGGCAGTTGCTCATTGAT
TATCTGCGTGCTGCGAGCTA

Product: signal transduction histidine-protein kinase BaeS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPVPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSEDELGRLAEDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETLASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGLSITVELPLERDLQREV

Sequences:

>Translated_467_residues
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPVPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSEDELGRLAEDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETLASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGLSITVELPLERDLQREV
>Mature_467_residues
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPVPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSEDELGRLAEDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETLASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGLSITVELPLERDLQREV

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=467, Percent_Identity=96.1456102783726, Blast_Score=897, Evalue=0.0,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=29.6551724137931, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=29.0441176470588, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=29.2372881355932, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786912, Length=276, Percent_Identity=29.7101449275362, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787374, Length=299, Percent_Identity=26.4214046822742, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=28.6885245901639, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=26.8595041322314, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=29.2, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=254, Percent_Identity=29.1338582677165, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788279, Length=292, Percent_Identity=25.6849315068493, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787894, Length=307, Percent_Identity=24.1042345276873, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790551, Length=299, Percent_Identity=27.7591973244147, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789808, Length=247, Percent_Identity=28.3400809716599, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=26.1363636363636, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082128, Length=292, Percent_Identity=22.9452054794521, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=320, Percent_Identity=23.125, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789403, Length=297, Percent_Identity=28.956228956229, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=250, Percent_Identity=24.4, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52099; Mature: 52099

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHHHHHHHHH
QYAQHGNWRFLRNNDRFVFQILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECC
RAPVPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFDRQQRQTSWLIVALSTLLAAL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSEDELGRLAEDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETLASLQAEVGTLTKLVDDLHQLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKAPVDLIPLLEVAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNN
CCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHH
LLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDDQLQKLFERFYRTEGSRNRAS
HHHHCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GGSGLGLAICLNIVEAHNGRIIAAHSPFGGLSITVELPLERDLQREV
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHCCC
>Mature Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHHHHHHHHH
QYAQHGNWRFLRNNDRFVFQILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECC
RAPVPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFDRQQRQTSWLIVALSTLLAAL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSEDELGRLAEDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETLASLQAEVGTLTKLVDDLHQLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKAPVDLIPLLEVAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNN
CCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHH
LLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDDQLQKLFERFYRTEGSRNRAS
HHHHCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GGSGLGLAICLNIVEAHNGRIIAAHSPFGGLSITVELPLERDLQREV
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]