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The map label for this gene is add [H]

Identifier: 218689569

GI number: 218689569

Start: 1784209

End: 1785210

Strand: Direct

Name: add [H]

Synonym: ECED1_1823

Alternate gene names: 218689569

Gene position: 1784209-1785210 (Clockwise)

Preceding gene: 218689568

Following gene: 218689571

Centisome position: 34.25

GC content: 53.39

Gene sequence:

>1002_bases
ATGATTGATACCACCCTGCCATTAACTGATATCCATCGCCACCTTGATGGCAACATTCGTCCCCAGACCATTCTTGAACT
TGGCCGCCAGTATAATATCTTGCTTCCTGCACAATCCCTGGAAACACTGATTCCCCACGTTCAGGTCATTGCCAACGAAC
CCGATCTGGTGAGCTTTCTGACTAAACTTGACTGGGGCGTTAAAGTTCTCGCCTCTCTTGATGCCTGCCGCCGCGTGGCA
TTTGAAAACATTGAAGATGCAGCCCGTAACGGCCTGCACTATGTCGAGCTGCATTTTTCACCAGGCTACATGGCAATGGC
ACATCAGCTGCCTGTAGCGGGTGTTGTCGAAGCGGTGATCGATGGCGTACGTGAAGGTTGCCGCACCTTTGGTGTGCAGG
CGAAGCTTATCGGTATTATGAGCCGGACCTTCGGCGAAGCCGCCTGTCAGCAAGAGCTGGAGGCCTTTTTAGCCCACCGT
GACCAGATTACCGCACTTGATTTAGCCGGTGATAAACTTGGTTTCCCGGGAAGTCTGTTCCTTTCTCATTTCAACCGCGC
GCGTGATGCGGGCTGGCATATTACCGTCCATGCAGGCGAAGCTGCCGGACCGGAAAGCATCTGGCAGGCGATTCGTGAAC
TGGGGGCGGAGCGTATTGGACATGGCGTAAAAGCCATTGAAGATCGGGCGCTGATGGATTTTCTCGCCGAGCAACAAATT
GGTATTGAATCCTGTCTGACCTCCAATATTCAGACCAGCACCGTGGCGGATCTGGCTGCACATCCGCTGAAAACGTTCCT
TGAGCATGGCATTCGTGCCAGCATTAACACTGACGATCCAGGCGTGCAGGGAGTGGATATCATTCACGAATATACCGTTG
CCGCGCCAGCTGCTGGGTTATCCCGCGAGCAAATCCGCCAGGCACAGATTAATGGTCTGGAAATGGCTTTCCTCAGCGCA
GAGGAAAAACGCGCACTGCGAGAAAAAGTCGCCGCGAAGTAA

Upstream 100 bases:

>100_bases
CAATTGCGCAACGTAAAAAATCGTTGCGCAATCGTGGATTTTTACCCTGCTTTGTTTTTATAATGGTGCGCACTTTTATA
TCCAGAAAAAGAGTGCGACC

Downstream 100 bases:

>100_bases
CAAAAATGGATGGTGCTAATTGCACCATCCCCTTTTCACGCAAGGCACAAAGTCGCGCGATGTTTGGCGGATTCGATGCC
CAGCTCAATCAACTCCATTA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNILLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVA
FENIEDAARNGLHYVELHFSPGYMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
DQITALDLAGDKLGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQI
GIESCLTSNIQTSTVADLAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSA
EEKRALREKVAAK

Sequences:

>Translated_333_residues
MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNILLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVA
FENIEDAARNGLHYVELHFSPGYMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
DQITALDLAGDKLGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQI
GIESCLTSNIQTSTVADLAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSA
EEKRALREKVAAK
>Mature_333_residues
MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNILLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVA
FENIEDAARNGLHYVELHFSPGYMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
DQITALDLAGDKLGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQI
GIESCLTSNIQTSTVADLAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSA
EEKRALREKVAAK

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=339, Percent_Identity=32.4483775811209, Blast_Score=155, Evalue=7e-38,
Organism=Escherichia coli, GI1787910, Length=333, Percent_Identity=98.4984984984985, Blast_Score=669, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17538512, Length=339, Percent_Identity=30.3834808259587, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32565969, Length=339, Percent_Identity=30.3834808259587, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324188, Length=338, Percent_Identity=26.3313609467456, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24645260, Length=335, Percent_Identity=26.2686567164179, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006650
- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36367; Mature: 36367

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNILLPAQSLETLIPHVQVIANEPDLVSFL
CCCCCCCHHHHHHHHCCCCCHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHH
TKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELHFSPGYMAMAHQLPVAGVVEAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCHHHHHHHHH
DGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHRDQITALDLAGDKLGFPGSLF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHH
LSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQI
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
GIESCLTSNIQTSTVADLAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGL
CHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCC
SREQIRQAQINGLEMAFLSAEEKRALREKVAAK
CHHHHHHHHHCCHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNILLPAQSLETLIPHVQVIANEPDLVSFL
CCCCCCCHHHHHHHHCCCCCHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHH
TKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELHFSPGYMAMAHQLPVAGVVEAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCHHHHHHHHH
DGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHRDQITALDLAGDKLGFPGSLF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHH
LSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQI
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
GIESCLTSNIQTSTVADLAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGL
CHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCC
SREQIRQAQINGLEMAFLSAEEKRALREKVAAK
CHHHHHHHHHCCHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA