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The map label for this gene is modD [H]

Identifier: 218689140

GI number: 218689140

Start: 1326642

End: 1327496

Strand: Reverse

Name: modD [H]

Synonym: ECED1_1339

Alternate gene names: 218689140

Gene position: 1327496-1326642 (Counterclockwise)

Preceding gene: 218689141

Following gene: 218689139

Centisome position: 25.48

GC content: 51.81

Gene sequence:

>855_bases
ATGATTTTCTTTTCTCAGGCACAAATCGATGCGTTACTGCTGGAAGATATCCAGGGCGGTGACCTGACCACACGAGCATT
AAATATTGGACACCAGCATGGCTATATAGAGTTTTTTCTCCGTCAGGGCGGCTGCGTCAGCGGAATTTCTGTCGCGTGTA
AGATGTTAACTACGCTGGGATTAACTATTGATGACGCGGTCAGCGACGGTTCACAAGCGAACGCGGGTCAGCGGCTAATC
CGTGCGCAAGGTAATGCCGCAGCACTTCATCAGGGATGGAAGGCAGTCCAGAATGTGCTGGAGTGGAGTTGCGGTGTTTC
TGATTATCTCGCTCAAATGCTGGCGTTACTTCGTGAACGTTACCCTGATGGCAATATCGCCTGCACCCGAAAAGCAATTC
CGGGCACCCGCTTACTGGCCTCGCAGGCAATTCTGGCTGCCGGAGGACTGATTCATCGTGCCGGATGTGCGGAAACCATA
TTATTGTTTGCCAACCACCGCCATTTTCTTCATGACAATCAGGACTGGTCAGGCGCAATCAATCAGTTACGTCGCCACGC
ACCCGAGAAGAAAATAGTTGTTGAAGCCGACACGCCGAAAGAGGCAATCGCCGCGTTACGCGCGCAACCAGACGTACTTC
AGCTCGACAAATTTAGTCCGCAACAGGCAACTGAAATTGCGCAAATAGCACCGTCGCTGGCTCCCCACTGCACGCTGGCT
CTGACCGGCGGAATTAATCTGACAACACTCAAAAATTACCTCGACTGCGGCATTCGCCTTTTTATTACCTCCGCGCCTTA
TTACGCGGCACCTGCTGACATTAAAGTCAGTCTGCAACCCGCAGCCTCTATTTAA

Upstream 100 bases:

>100_bases
TATATCGCTGGTATCAACAACAAGATGCTCGTGCCCTCGCCCCTGCCAGCCGCGACTGGGCGCTCATCTGGTGGGATAGC
GTACCGCAGGAGACACTGCG

Downstream 100 bases:

>100_bases
TTCTTTGTTAAACGGAATTTATTCTATGAGACTCAAAAAACGTTATCTCTGCACAGTATTATCACTTGCCTTTACCCAGC
AGTCCGTAGCGGCTCAGGAG

Product: molybdenum transport protein ModD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MIFFSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFLRQGGCVSGISVACKMLTTLGLTIDDAVSDGSQANAGQRLI
RAQGNAAALHQGWKAVQNVLEWSCGVSDYLAQMLALLRERYPDGNIACTRKAIPGTRLLASQAILAAGGLIHRAGCAETI
LLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLA
LTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI

Sequences:

>Translated_284_residues
MIFFSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFLRQGGCVSGISVACKMLTTLGLTIDDAVSDGSQANAGQRLI
RAQGNAAALHQGWKAVQNVLEWSCGVSDYLAQMLALLRERYPDGNIACTRKAIPGTRLLASQAILAAGGLIHRAGCAETI
LLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLA
LTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI
>Mature_284_residues
MIFFSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFLRQGGCVSGISVACKMLTTLGLTIDDAVSDGSQANAGQRLI
RAQGNAAALHQGWKAVQNVLEWSCGVSDYLAQMLALLRERYPDGNIACTRKAIPGTRLLASQAILAAGGLIHRAGCAETI
LLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLA
LTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family [H]

Homologues:

Organism=Homo sapiens, GI45269149, Length=263, Percent_Identity=25.0950570342205, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1786299, Length=200, Percent_Identity=27.5, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321162, Length=259, Percent_Identity=26.6409266409266, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412 [H]

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N [H]

EC number: 2.4.2.-

Molecular weight: Translated: 30543; Mature: 30543

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFFSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFLRQGGCVSGISVACKMLTTLG
CEEECCHHHHHHHHHHCCCCCEEHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
LTIDDAVSDGSQANAGQRLIRAQGNAAALHQGWKAVQNVLEWSCGVSDYLAQMLALLRER
CEEHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
YPDGNIACTRKAIPGTRLLASQAILAAGGLIHRAGCAETILLFANHRHFLHDNQDWSGAI
CCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCHHCCCCCCHHHHH
NQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLA
HHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCCCEEEE
LTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI
EECCCCHHHHHHHHCCCEEEEEECCCCEECCCCEEEEECCCCCC
>Mature Secondary Structure
MIFFSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFLRQGGCVSGISVACKMLTTLG
CEEECCHHHHHHHHHHCCCCCEEHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
LTIDDAVSDGSQANAGQRLIRAQGNAAALHQGWKAVQNVLEWSCGVSDYLAQMLALLRER
CEEHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
YPDGNIACTRKAIPGTRLLASQAILAAGGLIHRAGCAETILLFANHRHFLHDNQDWSGAI
CCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCHHCCCCCCHHHHH
NQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLA
HHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCCCEEEE
LTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI
EECCCCHHHHHHHHCCCEEEEEECCCCEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA