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The map label for this gene is dsbB [H]

Identifier: 218689128

GI number: 218689128

Start: 1312331

End: 1312861

Strand: Reverse

Name: dsbB [H]

Synonym: ECED1_1327

Alternate gene names: 218689128

Gene position: 1312861-1312331 (Counterclockwise)

Preceding gene: 218689129

Following gene: 218689122

Centisome position: 25.2

GC content: 52.54

Gene sequence:

>531_bases
ATGTTGCGATTTTTGAACCAATGTTCACAAGGCCGGGGTGCATGGCTGTTGATGGCGTTTACTGCTCTGGCACTGGAACT
GACGGCGCTGTGGTTCCAGCATGTGATGTTACTGAAACCTTGCGTGCTCTGTATTTATGAACGCTGCGCGTTATTCGGCG
TTCTGGGTGCTGCGCTGATTGGCGCGATCGCCCCGAAAACTCCGCTGCGTTATGTAGCGATGGTTATCTGGTTGTATAGT
GCGTTCCGCGGTGTGCAGTTAACTTACGAGCACACCATGCTTCAGCTCTATCCTTCGCCGTTTGCGACCTGTGATTTTAT
GGCTCGTTTCCCGGAATGGCTGCCGCTGGATAAATGGGTGCCGCAAGTGTTTGTCGCCTCTGGCGATTGCGCCGAGCGTC
AGTGGGAATTTTTAGGTCTGGAAATGCCGCAGTGGCTGCTCGGTATTTTTATCACTTACCTGATTGTCGCGGTGCTGGTG
GTGATTTCCCAGCCGTTTAAAGCGAAAAAACGTGACCTGTTCGGTCGCTAA

Upstream 100 bases:

>100_bases
GATAATTGTCCAATTGCGTCCTATTTTTGCTGCCTCCTGGTGGCGCAGCGAATGAATTGGTTTAAACTGCGCACTCTATG
CATATTGCAGGGAAATGATT

Downstream 100 bases:

>100_bases
TCCATTCGGCGCTCCTGCGGGAGCGCTTTTTCCTGCCGCTATGTTTATTTGACCCGCAGTAAATCAGAACTTCGCGTTGT
ATAACATGGTGAAAGCATGG

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLCIYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYS
AFRGVQLTYEHTMLQLYPSPFATCDFMARFPEWLPLDKWVPQVFVASGDCAERQWEFLGLEMPQWLLGIFITYLIVAVLV
VISQPFKAKKRDLFGR

Sequences:

>Translated_176_residues
MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLCIYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYS
AFRGVQLTYEHTMLQLYPSPFATCDFMARFPEWLPLDKWVPQVFVASGDCAERQWEFLGLEMPQWLLGIFITYLIVAVLV
VISQPFKAKKRDLFGR
>Mature_176_residues
MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLCIYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYS
AFRGVQLTYEHTMLQLYPSPFATCDFMARFPEWLPLDKWVPQVFVASGDCAERQWEFLGLEMPQWLLGIFITYLIVAVLV
VISQPFKAKKRDLFGR

Specific function: Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by oxidizing the DsbA protein [H]

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family [H]

Homologues:

Organism=Escherichia coli, GI1787433, Length=176, Percent_Identity=98.2954545454545, Blast_Score=353, Evalue=4e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003752
- InterPro:   IPR022920 [H]

Pfam domain/function: PF02600 DsbB [H]

EC number: NA

Molecular weight: Translated: 20158; Mature: 20158

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLCIYERCALFGVLGAALI
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFATCDFMARFPEWLPLDKWV
HHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHH
PQVFVASGDCAERQWEFLGLEMPQWLLGIFITYLIVAVLVVISQPFKAKKRDLFGR
HHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC
>Mature Secondary Structure
MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLCIYERCALFGVLGAALI
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFATCDFMARFPEWLPLDKWV
HHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHH
PQVFVASGDCAERQWEFLGLEMPQWLLGIFITYLIVAVLVVISQPFKAKKRDLFGR
HHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]