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The map label for this gene is fhuE [H]

Identifier: 218689054

GI number: 218689054

Start: 1245343

End: 1247532

Strand: Reverse

Name: fhuE [H]

Synonym: ECED1_1245

Alternate gene names: 218689054

Gene position: 1247532-1245343 (Counterclockwise)

Preceding gene: 218689063

Following gene: 218689039

Centisome position: 23.95

GC content: 50.05

Gene sequence:

>2190_bases
ATGCTTTCGACACAATTTAACAGGGATAATCAACATCAAGCTATCATCAAACCGTCACTCCTTGCCGGTTGCATAGCACT
GGCACTATTACCTTCCGCCGCTTTTGCTGCACCAGTCACTGAAGAAACGGTGATTGTTGAGGGTTCAGCCACAGCCCCAG
ATGATGGCGAAAATGATTACAACGTAACGTCTACCTCTGCGGGTACAAAAATGCAGATGACTCAACGTGATATTCCTCAG
TCGGTCACTATTGTTAGCCAGCAGCGGATGGAAGATCAGCAGTTACAAACGCTGGGCGAAGTGATGGAAAACACGCTGGG
GATCAGCAAAAGTCAGGCGGATTCCGATCGTGCTCTTTATTATTCCCGCGGATTCCAGATCGATAACTATATGGTTGATG
GTATCCCCACCTATTTTGAATCGCGCTGGAATCTGGGCGACGCACTTTCTGATATGGCACTGTTTGAACGCGTAGAAGTA
GTGCGTGGCGCGACAGGCCTCATGACCGGGACGGGTAATCCATCTGCGGCAATTAATATGGTTCGAAAACACGCGACCAG
TCGTGAATTTAAAGGCGATGTCTCGGCGGAATACGGTAGCTGGAACAAAGAACGGTATGTGGCGGATTTACAAAGCCCAC
TCACCGAAGATGGTAAAATCCGCGCACGAATTGTCGGCGGCTACCAGAATAACGACTCATGGCTGGACCGCTACAACAGT
GAAAAGGCCTTCTTCTCCGGCATTGTCGATGCTGATTTAGGCGATCTTACGATGCTTTCAGCCGGTTACGAATATCAGCG
TATTGATGTTAATAGCCCAACCTGGGGTGGTTTACCGCGCTGGAATACTGATGGCAGCAGCAACAGTTACGATCGCGCAC
GCAGTACCGCACCTGACTGGGCGTACAACGATAAAGAGATCAACAAGGTCTTTATGACCCTGAAGCAGCGGTTTGCTGAT
ACCTGGCAAGCGACGCTGAATGCCACCCACTCTGAAGTCGAATTTGACAGCAAAATGATGTATGTCGATGCCTATGTAAA
CAAAGCGGATGGTATGCTGGTTGGGCCATACAGTAATTATGGACCTGGTTTTGATTATGTCGGCGGCACCGGTTGGAACA
GCGGCAAACGTAAAGTTGATGCGCTGGATTTGTTCGCTGACGGTAGTTATGAATTGTTTGGTCGTCAGCACAATCTAATG
TTTGGTGGCAGTTACAGCAAACAAAACAATCGTTACTTCAGTTCATGGGCCAACATCTTCCCGGATGAAATTGGCAGTTT
CTACAACTTTAATGGCAATTTCCCACAAACCGACTGGTCACCACAGAGCCTGGCGCAGGACGATACCACACATATGAAAT
CGTTATATGCTGCCACTCGTGTCACCCTTGCCGATCCGCTGCATCTGATCCTCGGCGCACGTTATACCAACTGGCGGGTT
GATACGCTGACTTACAGCATGGAGAAAAACCACACCACGCCTTACGCTGGTCTGGTGTTTGACATCAATGACAACTGGTC
GACCTACGCCAGCTATACCTCTATTTTCCAGCCGCAAAATGATCGTGACAGTTCAGGCAAATATCTGACTCCAATCACCG
GTAACAACTACGAGCTGGGTCTGAAATCGGACTGGATGAATAGCCGTCTGACCACCACGTTAGCCATCTTCCGTATTGAG
CAGGATAATGTCGCTCAGTCCACCGGTACACCTATCCCCGGCAGCAACGGCGAAACCGCCTATAAAGCGGTGGATGGGAC
AGTCAGTAAAGGTGTGGAATTTGAACTCAACGGCGCAATTACCGACAACTGGCAGCTGACGTTTGGCGCAACGCGCTATA
TTGCAGAGGATAACGAAGGAAACGCCGTTAATCCTAATCTGCCACGCACCACGGTTAAAATGTTCACCAGCTATCGGTTG
CCTGTCATGCCAGAGTTGACGGTCGGCGGTGGTGTTAACTGGCAAAATCGCGTGTATACCGACACCGTGACGCCGTATGG
CACCTTCCGCGCCGAGCAAGGCAGCTACGCGCTGGTGGATCTCTTCACCCGCTACCAGGTGACGAAAAACTTCTCGTTGC
AGGGGAACGTCAATAACCTGTTCGACAAAACCTACGATACCAACGTGGAAGGTTCTATCGTCTACGGCGCACCGCGTAAT
TTCAGCATTACCGGCACGTATCAATTCTGA

Upstream 100 bases:

>100_bases
CATTTGCATTTACATACAAAATTATTCGCACACTAAATATAACCGCTCATCACCCTGCTCCGGCATGAGCCTGACGCCAA
CATAAACCAAGAGATTTCAA

Downstream 100 bases:

>100_bases
ATAACACCTGTAAAAAAGGCAGCCATCTGGCTGCCTTAGTCTCCCCAACGTCTTACGGATTAGTGGTTACGGATGTACTC
ATCCATCTCGGTTTTCAGGT

Product: ferric-rhodotorulic acid outer membrane transporter

Products: NA

Alternate protein names: Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid [H]

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MLSTQFNRDNQHQAIIKPSLLAGCIALALLPSAAFAAPVTEETVIVEGSATAPDDGENDYNVTSTSAGTKMQMTQRDIPQ
SVTIVSQQRMEDQQLQTLGEVMENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDGKIRARIVGGYQNNDSWLDRYNS
EKAFFSGIVDADLGDLTMLSAGYEYQRIDVNSPTWGGLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQRFAD
TWQATLNATHSEVEFDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYELFGRQHNLM
FGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDWSPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRV
DTLTYSMEKNHTTPYAGLVFDINDNWSTYASYTSIFQPQNDRDSSGKYLTPITGNNYELGLKSDWMNSRLTTTLAIFRIE
QDNVAQSTGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRL
PVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGAPRN
FSITGTYQF

Sequences:

>Translated_729_residues
MLSTQFNRDNQHQAIIKPSLLAGCIALALLPSAAFAAPVTEETVIVEGSATAPDDGENDYNVTSTSAGTKMQMTQRDIPQ
SVTIVSQQRMEDQQLQTLGEVMENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDGKIRARIVGGYQNNDSWLDRYNS
EKAFFSGIVDADLGDLTMLSAGYEYQRIDVNSPTWGGLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQRFAD
TWQATLNATHSEVEFDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYELFGRQHNLM
FGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDWSPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRV
DTLTYSMEKNHTTPYAGLVFDINDNWSTYASYTSIFQPQNDRDSSGKYLTPITGNNYELGLKSDWMNSRLTTTLAIFRIE
QDNVAQSTGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRL
PVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGAPRN
FSITGTYQF
>Mature_729_residues
MLSTQFNRDNQHQAIIKPSLLAGCIALALLPSAAFAAPVTEETVIVEGSATAPDDGENDYNVTSTSAGTKMQMTQRDIPQ
SVTIVSQQRMEDQQLQTLGEVMENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDGKIRARIVGGYQNNDSWLDRYNS
EKAFFSGIVDADLGDLTMLSAGYEYQRIDVNSPTWGGLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQRFAD
TWQATLNATHSEVEFDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYELFGRQHNLM
FGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDWSPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRV
DTLTYSMEKNHTTPYAGLVFDINDNWSTYASYTSIFQPQNDRDSSGKYLTPITGNNYELGLKSDWMNSRLTTTLAIFRIE
QDNVAQSTGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRL
PVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGAPRN
FSITGTYQF

Specific function: Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid [H]

COG id: COG4773

COG function: function code P; Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787344, Length=729, Percent_Identity=98.7654320987654, Blast_Score=1489, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81302; Mature: 81302

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00430 TONB_DEPENDENT_REC_1 ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTQFNRDNQHQAIIKPSLLAGCIALALLPSAAFAAPVTEETVIVEGSATAPDDGENDY
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCCCCCC
NVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVMENTLGISKSQADSDRALY
EEEECCCCCEEEEHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
YSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEVVRGATGLMTGTGNPSAAINM
EECCEEECCEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
VRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDGKIRARIVGGYQNNDSWLDRYNS
HHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHCCC
EKAFFSGIVDADLGDLTMLSAGYEYQRIDVNSPTWGGLPRWNTDGSSNSYDRARSTAPDW
CHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCCC
AYNDKEINKVFMTLKQRFADTWQATLNATHSEVEFDSKMMYVDAYVNKADGMLVGPYSNY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEEEEEECCCCCEEECCCCCC
GPGFDYVGGTGWNSGKRKVDALDLFADGSYELFGRQHNLMFGGSYSKQNNRYFSSWANIF
CCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEECCCCCEEECCCCCCCCCCHHHHHHHCC
PDEIGSFYNFNGNFPQTDWSPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRV
HHHHCCEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHEECCCCHHHHHCCCCCCEEE
DTLTYSMEKNHTTPYAGLVFDINDNWSTYASYTSIFQPQNDRDSSGKYLTPITGNNYELG
EEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEC
LKSDWMNSRLTTTLAIFRIEQDNVAQSTGTPIPGSNGETAYKAVDGTVSKGVEFELNGAI
CCCCCCCCHHEEEEEEEEECCCCCHHHCCCCCCCCCCCEEEEEECCHHHCCEEEEECCEE
TDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYT
ECCEEEEECEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEE
DTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGAPRN
CCCCCCCCEECCCCCEEEEEHHHHHEEEECEEECCCHHHHHCCCCCCCCCCEEEECCCCC
FSITGTYQF
EEEEEEECC
>Mature Secondary Structure
MLSTQFNRDNQHQAIIKPSLLAGCIALALLPSAAFAAPVTEETVIVEGSATAPDDGENDY
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCCCCCC
NVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVMENTLGISKSQADSDRALY
EEEECCCCCEEEEHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
YSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEVVRGATGLMTGTGNPSAAINM
EECCEEECCEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
VRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDGKIRARIVGGYQNNDSWLDRYNS
HHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHCCC
EKAFFSGIVDADLGDLTMLSAGYEYQRIDVNSPTWGGLPRWNTDGSSNSYDRARSTAPDW
CHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCCC
AYNDKEINKVFMTLKQRFADTWQATLNATHSEVEFDSKMMYVDAYVNKADGMLVGPYSNY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEEEEEECCCCCEEECCCCCC
GPGFDYVGGTGWNSGKRKVDALDLFADGSYELFGRQHNLMFGGSYSKQNNRYFSSWANIF
CCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEECCCCCEEECCCCCCCCCCHHHHHHHCC
PDEIGSFYNFNGNFPQTDWSPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRV
HHHHCCEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHEECCCCHHHHHCCCCCCEEE
DTLTYSMEKNHTTPYAGLVFDINDNWSTYASYTSIFQPQNDRDSSGKYLTPITGNNYELG
EEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEC
LKSDWMNSRLTTTLAIFRIEQDNVAQSTGTPIPGSNGETAYKAVDGTVSKGVEFELNGAI
CCCCCCCCHHEEEEEEEEECCCCCHHHCCCCCCCCCCCEEEEEECCHHHCCEEEEECCEE
TDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYT
ECCEEEEECEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEE
DTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGAPRN
CCCCCCCCEECCCCCEEEEEHHHHHEEEECEEECCCHHHHHCCCCCCCCCCEEEECCCCC
FSITGTYQF
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162465; 8905232; 9278503; 3032906 [H]