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The map label for this gene is rutG [H]

Identifier: 218688971

GI number: 218688971

Start: 1164969

End: 1166297

Strand: Reverse

Name: rutG [H]

Synonym: ECED1_1162

Alternate gene names: 218688971

Gene position: 1166297-1164969 (Counterclockwise)

Preceding gene: 218688972

Following gene: 218688968

Centisome position: 22.39

GC content: 53.65

Gene sequence:

>1329_bases
ATGGCAATGTTCGGTTTTCCTCACTGGCAGTTAAAATCGACCTCTACAGAGAGCGGCGTGGTCGCGCCGGATGAACGATT
GCCGTTTGCTCAAACGGCAGTAATGGGCGTTCAACACGCGGTGGCGATGTTTGGCGCGACGGTGTTAATGCCGATTCTGA
TGGGGCTGGATCCCAATCTTTCCATTTTAATGTCGGGGATCGGCACGTTACTGTTTTTCTTTATTACCGGCGGGCGCGTG
CCCAGTTATCTCGGTTCCAGCGCGGCTTTTGTCGGCGTGGTGATTGCCGCGACGGGCTTTAATGGTCAGGGAATTAATCC
GAATATCAGCATCGCGCTGGGCGGGATTATCGCCTGTGGGCTGGTTTATACCGTCATTGGCCTGGTGGTGATGAAAATCG
GTACGCGCTGGATTGAACGACTAATGCCGCCGGTTGTGACGGGTGCGGTAGTGATGGCGATTGGCCTGAACTTAGCGCCT
ATCGCAGTGAAAAATGTATCGGCTTCGGCCTTTGATAGCTGGATGGCGGTAATGACGGTGCTATGTATTGGGCTGGTGGC
CGTATTTACCCGTGGCATGATCCAGCGATTATTGATTCTCGTAGGATTAATTGTCGCCTGTCTGCTGTATGGCGTGATGA
CCAACGTTTTAGGGCTGGGAAAAGCCGTCGATTTTACTCTCGTCAGCCATGCTGCCTGGTTCGGTCTGCCACATTTTTCC
ACTCCTGCTTTTAATGGTCAGGCAATGATGCTGATTGCGCCCGTGGCGGTGATTCTGGTGGCGGAAAACTTAGGTCATCT
CAAGGCGGTCGCCGGGATGACCGGACGCAATATGGACCCGTATATGGGGCGGGCATTCGTAGGCGATGGGCTGGCGACGA
TGCTTTCTGGCTCTGTCGGCGGTAGCGGCGTAACCACCTACGCCGAGAATATCGGTGTGATGGCCGTGACAAAAGTCTAC
TCGACGCTGGTGTTTGTTGCCGCTGCCGTCATCGCCATGCTGTTGGGCTTTTCGCCGAAATTTGGCGCGCTGATCCATAC
TATTCCGGCTGCGGTGATTGGTGGTGCATCAATTGTTGTGTTCGGGCTGATTGCCGTCGCAGGCGCACGGATCTGGGTAC
AAAACAGTGTGGATTTAAGCCAGAACGGTAATTTGATTATGGTCGCAGTAACCTTAGTGCTGGGTGCGGATGATTTTGCT
CTCACACTGGGCGGTTTTACGTTGGGAGGGATCGGTACAGCCACCTTTGGCGCGATTTTACTCAATGCGTTGTTAAGCAG
AAGGTTGGTTGACGTTCCACCGCCAGAAGTTGTTCATCAGGAGCCATAA

Upstream 100 bases:

>100_bases
CGATTCATCGTCACGCCACACCCTACGGGCTGGTGTGGTTCGATCGCAGTTATCACGCGCTGATGCGCCCTGCTTGTTAA
CCTCCTTAAGGAGACAGCTG

Downstream 100 bases:

>100_bases
ACAGAAAACCGCCGGGGTAACCGGCGGTGATGGCGTTTTGACGAGCTACAGACAAAAATGCATGTGTCATTGATTAGCCC
GGCTAGTTGTCGCTTTTACC

Product: pyrimidine transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRV
PSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVKNVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
TPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVY
STLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNSVDLSQNGNLIMVAVTLVLGADDFA
LTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVVHQEP

Sequences:

>Translated_442_residues
MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRV
PSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVKNVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
TPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVY
STLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNSVDLSQNGNLIMVAVTLVLGADDFA
LTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVVHQEP
>Mature_441_residues
AMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVP
SYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPI
AVKNVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFST
PAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYS
TLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNSVDLSQNGNLIMVAVTLVLGADDFAL
TLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVVHQEP

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=442, Percent_Identity=99.0950226244344, Blast_Score=856, Evalue=0.0,
Organism=Escherichia coli, GI1788843, Length=425, Percent_Identity=36.7058823529412, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI87082181, Length=456, Percent_Identity=25.4385964912281, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI87082178, Length=405, Percent_Identity=26.9135802469136, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=174, Percent_Identity=35.632183908046, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17542260, Length=174, Percent_Identity=35.632183908046, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17542262, Length=176, Percent_Identity=30.6818181818182, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17558856, Length=181, Percent_Identity=29.8342541436464, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17541904, Length=175, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356175, Length=176, Percent_Identity=30.6818181818182, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45602; Mature: 45471

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNL
CCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACG
HHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHEEEECCCCCCCCCCCEEHHHHHHHHH
LVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKNVSASAFDSWMAVMTV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHH
LCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
TPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVG
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHCHHHHCCCHHHHHCCCCC
GSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHH
FGLIAVAGARIWVQNSVDLSQNGNLIMVAVTLVLGADDFALTLGGFTLGGIGTATFGAIL
HHHHHHHCCCEEEECCCCCCCCCCEEEEEHHHHHCCCCCEEEECCEEECCHHHHHHHHHH
LNALLSRRLVDVPPPEVVHQEP
HHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]