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The map label for this gene is wrbA [H]

Identifier: 218688892

GI number: 218688892

Start: 1100988

End: 1101566

Strand: Reverse

Name: wrbA [H]

Synonym: ECED1_1083

Alternate gene names: 218688892

Gene position: 1101566-1100988 (Counterclockwise)

Preceding gene: 218688893

Following gene: 218688891

Centisome position: 21.15

GC content: 54.23

Gene sequence:

>579_bases
ATGATAAAGCATATCCTTAGACATGTTGAAACGATGGCACGCGCAGTTGCTGAGGGTGCAAGCAAAGTGGATGGCGCAGA
AGTTGTCGTTAAGCGTGTACCGGAAACCATGCCGCCGCAATTATTTGAAAAAGCAGGCGGTAAAACGCAAACTGCACCGG
TTGCAACCCCGCAAGAACTGGCCGATTACGACGCCATTATTTTTGGTACACCTACCCGCTTTGGTAACATGTCCGGTCAA
ATGCGTACCTTCCTCGACCAGACGGGCGGCCTGTGGGCTTCCGGCGCACTATACGGAAAACTGGCGAGCGTCTTTAGTTC
CACCGGTACTGGCGGCGGTCAGGAACAAACCATCACATCCACCTGGACGACCCTTGCGCATCACGGCATGGTGATTGTCC
CCATTGGCTACGCAGCGCAGGAATTATTTGACGTTTCACAGGTTCGCGGCGGTACGCCGTACGGCGCAACCACCATCGCA
GGCGGTGACGGTTCACGCCAGCCCAGCCAGGAAGAACTGTCTATTGCTCGTTATCAAGGGGAATATGTCGCAGGTCTGGC
AGTTAAACTTAACGGCTAA

Upstream 100 bases:

>100_bases
GCGTGACTCAGGTTGCTATGCTGAATAATGTCCTTAATGCCCGTGCCCCAGACGTGCCCCAAAGTGACCAGGAGGATGAA
ATAAAATTATATTTTTCAAA

Downstream 100 bases:

>100_bases
TCTTCAACAGGAGGATACGCATGCCAACTCAAGAAGCGAAAGCTCATCACGTCGGTGAATGGGCATCTCTGCGCAATACG
TCGCCGGAAATAGCCGAGGC

Product: putative flavoprotein

Products: NA

Alternate protein names: Trp repressor-binding protein [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MIKHILRHVETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQ
MRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIA
GGDGSRQPSQEELSIARYQGEYVAGLAVKLNG

Sequences:

>Translated_192_residues
MIKHILRHVETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQ
MRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIA
GGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
>Mature_192_residues
MIKHILRHVETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQ
MRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIA
GGDGSRQPSQEELSIARYQGEYVAGLAVKLNG

Specific function: Seems to enhance the formation and/or stability of noncovalent complexes between the trp repressor protein and operator-bearing DNA [H]

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=185, Percent_Identity=99.4594594594595, Blast_Score=374, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6320235, Length=184, Percent_Identity=46.7391304347826, Blast_Score=163, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6319849, Length=188, Percent_Identity=45.7446808510638, Blast_Score=158, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6319526, Length=196, Percent_Identity=35.7142857142857, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: NA

Molecular weight: Translated: 20204; Mature: 20204

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKHILRHVETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQEL
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCHHHH
ADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITS
HCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHHCCCCCCCCCCCHHH
TWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQG
HHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCC
EYVAGLAVKLNG
CEEEEEEEEECC
>Mature Secondary Structure
MIKHILRHVETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQEL
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCHHHH
ADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITS
HCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHHCCCCCCCCCCCHHH
TWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQG
HHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCC
EYVAGLAVKLNG
CEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA