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The map label for this gene is torC [H]

Identifier: 218688884

GI number: 218688884

Start: 1092254

End: 1093426

Strand: Direct

Name: torC [H]

Synonym: ECED1_1073

Alternate gene names: 218688884

Gene position: 1092254-1093426 (Clockwise)

Preceding gene: 218688882

Following gene: 218688885

Centisome position: 20.97

GC content: 51.41

Gene sequence:

>1173_bases
ATGCGGAAACTCTGGAACGCGCTACGCCGACCCAGTGCTCGTTGGTCGGTACTGGCGCTGGTCGCTACTGGGATTGTGAT
TGGCATTGCGCTGATTGTATTGCCACACGTTGGGATCAAAGTCACCAGCACAACCGAATTTTGTGTCAGTTGCCACAGTA
TGCAACCGGTGTATGAAGAATATAAACAGTCGGTGCATTTCCAGAACGCCTCCGGCGTGCGAGCTGAATGCCATGACTGT
CATATCCCGCCGGATATTCCAGGCATGGTGAAGCGCAAACTGGAAGCGAGCAACGACATTTACCAGACCTTTATTGCCCA
CTCCATTGATACACCTGAGAAATTTGAAGCCAAACGCGCGGAACTTGCCGAGCGTGAATGGGCGCGAATGAAAGAAAACA
ACTCGGCAACCTGCCGCTCCTGCCATAACTACGATGCGATGGATCATGCGAAGCAGCATCCTGAAGCGGCGCGTCAGATG
AAGGTGGCAGCGAAAGATAATCAATCCTGCATCGACTGTCATAAAGGTATTGCCCACCAGTTACCGGATATGAGTAGTGG
CTTCCGTAAGCAGTTCGATGAGCTGCGCGCCAGTGCTAATGATAGTGGTGACACGCTGTACTCCATTGATATTAAGCCGA
TTTATGCGGCGAAAGGCGATAAAGAAGCGTCTGGTTCTCTGCTGCCTGCTTCGGAAGTGAAAGTCCTTAAACGTGACGGC
GACTGGCTGCAAATTGAAATCACTGGCTGGACGGAAAGTGCAGGACGTCAGCGTGTACTCACCCAATTCCCAGGTAAACG
CATCTTTGTTGCCTCGATTCGTGGTGATGTGCAGCAGCAGGTGAAAACACTGGAGAAAACCACCGTTGCCGACACCAATA
CCGAGTGGAGCAAGTTGCAGGCCACTGCGTGGATGAAGAAAGGCGACATGGTGAACGATATCAAACCGATCTGGGCTTAT
GCGGATTCGCTGTACAACGGCACCTGTAACCAGTGCCACGGCGCACCGGAAATATCCCACTTTGACGCTAACGGTTGGAT
CGGCACGCTCAACGGCATGATTGGCTTTACCAGCCTCGATAAACGTGAAGAACGCACCTTGTTGAAATATCTGCAAATGA
ATGCGTCTGACACCGCAGGTAAAGCTCACGGCGATAAGAAGGAAGAAAAATAA

Upstream 100 bases:

>100_bases
TGTTCATATTCTGCCGTAAGCTATTCATCCTGACCAGTGCCGCTGTTCATATTTGCTCATTAAGATCGCTTCACTAAACC
ATAATTTTACAGGGGCTATT

Downstream 100 bases:

>100_bases
TGAACAATAACGATCTCTTTCAGGCATCACGTCGGCGTTTTCTGGCACAACTCGGCGGCTTAACCGTCGCCGGGATGCTG
GGGCCGTCATTGTTAACGCC

Product: trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MRKLWNALRRPSARWSVLALVATGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDC
HIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDG
DWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAY
ADSLYNGTCNQCHGAPEISHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK

Sequences:

>Translated_390_residues
MRKLWNALRRPSARWSVLALVATGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDC
HIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDG
DWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAY
ADSLYNGTCNQCHGAPEISHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK
>Mature_390_residues
MRKLWNALRRPSARWSVLALVATGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDC
HIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDG
DWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAY
ADSLYNGTCNQCHGAPEISHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal dom

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1787230, Length=390, Percent_Identity=99.4871794871795, Blast_Score=818, Evalue=0.0,
Organism=Escherichia coli, GI1788181, Length=350, Percent_Identity=35.1428571428571, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1788530, Length=186, Percent_Identity=49.4623655913978, Blast_Score=182, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 43611; Mature: 43611

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLWNALRRPSARWSVLALVATGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEE
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCHHHHH
YKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRA
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHH
ELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQ
HHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
LPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDG
CCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCHHHHHHEECCC
DWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQ
CEEEEEEECCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEISHFDANGWIGTLNGMIGFTSLD
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCEECCCCCEEECCCCEECCCCC
KREERTLLKYLQMNASDTAGKAHGDKKEEK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRKLWNALRRPSARWSVLALVATGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEE
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCHHHHH
YKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRA
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHH
ELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQ
HHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
LPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDG
CCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCHHHHHHEECCC
DWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQ
CEEEEEEECCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEISHFDANGWIGTLNGMIGFTSLD
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCEECCCCCEEECCCCEECCCCC
KREERTLLKYLQMNASDTAGKAHGDKKEEK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]