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The map label for this gene is hyaD [H]

Identifier: 218688871

GI number: 218688871

Start: 1078991

End: 1079578

Strand: Direct

Name: hyaD [H]

Synonym: ECED1_1059

Alternate gene names: 218688871

Gene position: 1078991-1079578 (Clockwise)

Preceding gene: 218688870

Following gene: 218688872

Centisome position: 20.71

GC content: 59.35

Gene sequence:

>588_bases
ATGAGCGAGCAACGCGTGGTGGTAATGGGGCTGGGCAACCTGCTGTGGGCCGATGAAGGCTTCGGCGTGCGGGTGGCGGA
ACGGCTGTATGCCCATTACCACTGGCCCGAGGATGTGGAGATTGTCGATGGCGGCACCCAAGGACTGAACTTGCTGGGGT
ATGTCGAAAGCGCCGGTCATCTGTTGATTCTCGATGCCATTGATTACGGGCTGGAACCCGGAACGCTACGAACGTATGCC
GGAGAACGCATTCCGGCTTATCTCAGCGCGAAGAAAATGAGCCTGCACCAGAACAGTTTCTCCGAAGTGCTGGCGCTGGC
AGATATCCGCGGACATCTGCCAGCACATATTGCCCTCGTCGGTCTGCAACCCGCGATGCTCGACGACTACGGCGGCAGCC
TGAGCGAACTGGCGCGGGAGCAACTGCCCGCTGCGGAACAGGCGGCGCTGGCGCAGCTGGCTGCGTGGGGAATTGTGCCG
CAACCGGCTAATGAATCGCGCTGTCTCAATTATGACTGTCTGTCGATGGAAAATTACGAAGGCGTTCGCTTGCGTCAGTA
CAGGATGAGGCTGGAGGAACAGGGATGA

Upstream 100 bases:

>100_bases
CGCTGCGTGAAGACATCATGTCCGACGACACGGTGATCTCCACTATGGTCAACGGCTACCGTAGCCACAAATTTGGCAAA
ATAAGTAACAAGGAGCGTTC

Downstream 100 bases:

>100_bases
GCAACGACACACCATTTAATGCGTTGTGGCAACGAATGCTGGCACGTGGCTGGACGCCGGTCAGTGAATGCCGTCTTGAC
GACTGGCTTACGCAAGCGCC

Product: hydrogenase 1 maturation protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEDVEIVDGGTQGLNLLGYVESAGHLLILDAIDYGLEPGTLRTYA
GERIPAYLSAKKMSLHQNSFSEVLALADIRGHLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQAALAQLAAWGIVP
QPANESRCLNYDCLSMENYEGVRLRQYRMRLEEQG

Sequences:

>Translated_195_residues
MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEDVEIVDGGTQGLNLLGYVESAGHLLILDAIDYGLEPGTLRTYA
GERIPAYLSAKKMSLHQNSFSEVLALADIRGHLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQAALAQLAAWGIVP
QPANESRCLNYDCLSMENYEGVRLRQYRMRLEEQG
>Mature_194_residues
SEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEDVEIVDGGTQGLNLLGYVESAGHLLILDAIDYGLEPGTLRTYAG
ERIPAYLSAKKMSLHQNSFSEVLALADIRGHLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQAALAQLAAWGIVPQ
PANESRCLNYDCLSMENYEGVRLRQYRMRLEEQG

Specific function: Protease involved in the C-terminal processing of hyaB, the large subunit of hydrogenase 1 (Potential) [H]

COG id: COG0680

COG function: function code C; Ni,Fe-hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A31 family [H]

Homologues:

Organism=Escherichia coli, GI1787209, Length=195, Percent_Identity=97.9487179487179, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1789367, Length=155, Percent_Identity=38.7096774193548, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004419
- InterPro:   IPR000671 [H]

Pfam domain/function: PF01750 HycI [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 21509; Mature: 21378

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEDVEIVDGGTQGLNLLGYVESAGH
CCCCEEEEEECCCEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEECCCCC
LLILDAIDYGLEPGTLRTYAGERIPAYLSAKKMSLHQNSFSEVLALADIRGHLPAHIALV
EEEEEEHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
GLQPAMLDDYGGSLSELAREQLPAAEQAALAQLAAWGIVPQPANESRCLNYDCLSMENYE
ECCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCC
GVRLRQYRMRLEEQG
CHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEDVEIVDGGTQGLNLLGYVESAGH
CCCEEEEEECCCEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEECCCCC
LLILDAIDYGLEPGTLRTYAGERIPAYLSAKKMSLHQNSFSEVLALADIRGHLPAHIALV
EEEEEEHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
GLQPAMLDDYGGSLSELAREQLPAAEQAALAQLAAWGIVPQPANESRCLNYDCLSMENYE
ECCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCC
GVRLRQYRMRLEEQG
CHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Ni [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180913; 8905232; 9278503 [H]