Definition Escherichia coli ED1a chromosome, complete genome.
Accession NC_011745
Length 5,209,548

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The map label for this gene is tfaD [H]

Identifier: 218688846

GI number: 218688846

Start: 1053182

End: 1055167

Strand: Direct

Name: tfaD [H]

Synonym: ECED1_1034

Alternate gene names: 218688846

Gene position: 1053182-1055167 (Clockwise)

Preceding gene: 218688845

Following gene: 218688847

Centisome position: 20.22

GC content: 52.67

Gene sequence:

>1986_bases
TTGCAAAGGGCGCAAATCAGTGTGCGCGGGCGGGGGATAAATTACCGGATTTACTCGATGAATATATCAGAGCAACAACT
GAATAATATGATGAGTGCTGTCACAACAGCATTACAGCCCCTGATAAGGGCATTGCCGGTGACGCCAGTTGAATGGGCTG
ATCAAAATTATTATCTGCCTAAAGAATCTTCATATGGTGAGGGAGAATGGAAAACGCTGCCGTTCCAGATCGCCATCATG
AACAGCATGGGGAATGATCAGATCCGGACTGTTAATCTGATTAAATCTGCCCGTGTTGGCTATACAAAGATGTTGCTGGG
AGTCGCCGGGTATTTTATTGAGCATAAATCCCGAAACAGTCTGCTTTTTCAGCCCACGGATTCTGCCGCTGAAGATTTTA
TGAAGTCTCACGTGGAGGCGACGATTCGGGACGTGCCATGCCTGAAAGATCTTTCCCCGTGGCTGGGACGTAAACATCGT
GACAATACTCTCACGCTGAAACGCTTTTCATCGGGGGTGGGCTTCTGGTGCCTGGGTGGTGCGGCAGCAAAAAACTACCG
TGAAAAATCCGTGGATGTGGTCTGCTATGACGAACTTTCCTCGTTCGAGCCGGATGTCGAAAAAGAGGGCTCGCCAACCC
TGCTGGGAGATAAGCGTATTGAGGGCTCTGTATGGCCCAAATCCATTCGCGGCTCGACGCCTAAAATCAAAGGCACCTGC
CAGATCGAAAAAGCGGCCAACGAGTCGGCGCATTTCATGCGTTTTTATGTGCCCTGCCCACACTGTGGGGAGGAGCTGTA
TCTGAAATTTGGCGATGAATCCACGCCTTTTGGCCTTAAATGGGAGAAGGACAGCCCCGAAAGCGTTTTCTACCTCTGTG
AACATCATGGCTGCGTGATCCATCAGTCTGAGCTTGACCAGAGCAACGGGCGGTGGATCTGTGAAAACACGGGGATGTGG
ACCCGTGACGGTCTGACGTTTTTCAGCGCCGCGGATAATGAAATTCCGCCGCCGCGCTCCATCACATTCCATATCTGGAC
GGCGTACAGTCCGTTCACCACCTGGGTACAGATTGTCTATGACTGGCTGGATGCACTGAAAGATCCCAACGGCCTGAAAA
CCTTTGTGAACACCACGCTGGGCGAGACCTGGGAAGAGGCCGTGGGCGAAAAACTCGATCACCAGGTACTGATGGATAAG
GTTGTGCGTTACACGGCGGCGGTGCCTGCCCGGGTGGTTTATCTGACGGCGGGCATTGACTCGCAGCGAAACCGTTTTGA
GATGTATGTCTGGGGATGGGCTCCGGGAGAGGAAGCCTTTCTGGTGGATAAAATCATCATTATGGGGCGTCCCGATGAGG
AAGAGACGCTGTTACGTGTGGATGTGGCGATCAACAAAAAATACCGCCATGCAGACGGAACCGAAATGACCATTTCCCGT
GTCTGCTGGGACACCGGGGGGATCGATGGCGAAATTGTCTATCAGAGGTCAAAAAAACACGGTGTTTTCCGGGTGCTGCC
GGTAAAAGGTGCATCTGTTTATGGCAAGCCGGTGATCACCATGCCAAAAACCCGCAATCAGCGGGGCGTGTATCTGTGCG
AAGTGGGGACGGACACCGCAAAAGAAATTCTCTATGCCCGTATGAAAGCCGAGCCCACGCCTGCGGATGAAGCCACGTCG
TATGCCATCCGTTTTCCTGATGATCCGGAGATTTTTTCGCAGACAGAGGCGCAGCAACTGGTCGCGGAAGAGCTTGTGGA
GAAGTGGGAAAAAGGAAAGATGCGTCTGCTGTGGGATAACAAAAAGCGGCGTAACGAAGCGCTGGACTGCCTGGTGTATG
CCTACGCGGCATTACGTGTGTCCGTGCAACGCTGGCAGCTTGATCTGGCTGTACTGGCAAAATCCCGGGAAGAAGATACG
ACCCGGCCAACCCTTAAAGAACTGGCAGCGAAGCTGTCCGGAGGAGTGAATGGTTACAGTCGCTGA

Upstream 100 bases:

>100_bases
GCAATGGCGTTATCCAGTACGCTTGATTCCATCCCTTTATCCATGCAGCGACAGTTTCCTGATTTAACACCGCGCCATCT
TGACCATCTGAAAACCCTTA

Downstream 100 bases:

>100_bases
ACTGCAGGCGCTGCGTCAGGCGCGCCTTGATTTATTAACCGGTAAACGGGTGGTGTCTGTCCAGAAAGATGGTCGCAGAA
TTGAATATACGGCAGCTTCT

Product: terminase large subunit (Gp2)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MQRAQISVRGRGINYRIYSMNISEQQLNNMMSAVTTALQPLIRALPVTPVEWADQNYYLPKESSYGEGEWKTLPFQIAIM
NSMGNDQIRTVNLIKSARVGYTKMLLGVAGYFIEHKSRNSLLFQPTDSAAEDFMKSHVEATIRDVPCLKDLSPWLGRKHR
DNTLTLKRFSSGVGFWCLGGAAAKNYREKSVDVVCYDELSSFEPDVEKEGSPTLLGDKRIEGSVWPKSIRGSTPKIKGTC
QIEKAANESAHFMRFYVPCPHCGEELYLKFGDESTPFGLKWEKDSPESVFYLCEHHGCVIHQSELDQSNGRWICENTGMW
TRDGLTFFSAADNEIPPPRSITFHIWTAYSPFTTWVQIVYDWLDALKDPNGLKTFVNTTLGETWEEAVGEKLDHQVLMDK
VVRYTAAVPARVVYLTAGIDSQRNRFEMYVWGWAPGEEAFLVDKIIIMGRPDEEETLLRVDVAINKKYRHADGTEMTISR
VCWDTGGIDGEIVYQRSKKHGVFRVLPVKGASVYGKPVITMPKTRNQRGVYLCEVGTDTAKEILYARMKAEPTPADEATS
YAIRFPDDPEIFSQTEAQQLVAEELVEKWEKGKMRLLWDNKKRRNEALDCLVYAYAALRVSVQRWQLDLAVLAKSREEDT
TRPTLKELAAKLSGGVNGYSR

Sequences:

>Translated_661_residues
MQRAQISVRGRGINYRIYSMNISEQQLNNMMSAVTTALQPLIRALPVTPVEWADQNYYLPKESSYGEGEWKTLPFQIAIM
NSMGNDQIRTVNLIKSARVGYTKMLLGVAGYFIEHKSRNSLLFQPTDSAAEDFMKSHVEATIRDVPCLKDLSPWLGRKHR
DNTLTLKRFSSGVGFWCLGGAAAKNYREKSVDVVCYDELSSFEPDVEKEGSPTLLGDKRIEGSVWPKSIRGSTPKIKGTC
QIEKAANESAHFMRFYVPCPHCGEELYLKFGDESTPFGLKWEKDSPESVFYLCEHHGCVIHQSELDQSNGRWICENTGMW
TRDGLTFFSAADNEIPPPRSITFHIWTAYSPFTTWVQIVYDWLDALKDPNGLKTFVNTTLGETWEEAVGEKLDHQVLMDK
VVRYTAAVPARVVYLTAGIDSQRNRFEMYVWGWAPGEEAFLVDKIIIMGRPDEEETLLRVDVAINKKYRHADGTEMTISR
VCWDTGGIDGEIVYQRSKKHGVFRVLPVKGASVYGKPVITMPKTRNQRGVYLCEVGTDTAKEILYARMKAEPTPADEATS
YAIRFPDDPEIFSQTEAQQLVAEELVEKWEKGKMRLLWDNKKRRNEALDCLVYAYAALRVSVQRWQLDLAVLAKSREEDT
TRPTLKELAAKLSGGVNGYSR
>Mature_661_residues
MQRAQISVRGRGINYRIYSMNISEQQLNNMMSAVTTALQPLIRALPVTPVEWADQNYYLPKESSYGEGEWKTLPFQIAIM
NSMGNDQIRTVNLIKSARVGYTKMLLGVAGYFIEHKSRNSLLFQPTDSAAEDFMKSHVEATIRDVPCLKDLSPWLGRKHR
DNTLTLKRFSSGVGFWCLGGAAAKNYREKSVDVVCYDELSSFEPDVEKEGSPTLLGDKRIEGSVWPKSIRGSTPKIKGTC
QIEKAANESAHFMRFYVPCPHCGEELYLKFGDESTPFGLKWEKDSPESVFYLCEHHGCVIHQSELDQSNGRWICENTGMW
TRDGLTFFSAADNEIPPPRSITFHIWTAYSPFTTWVQIVYDWLDALKDPNGLKTFVNTTLGETWEEAVGEKLDHQVLMDK
VVRYTAAVPARVVYLTAGIDSQRNRFEMYVWGWAPGEEAFLVDKIIIMGRPDEEETLLRVDVAINKKYRHADGTEMTISR
VCWDTGGIDGEIVYQRSKKHGVFRVLPVKGASVYGKPVITMPKTRNQRGVYLCEVGTDTAKEILYARMKAEPTPADEATS
YAIRFPDDPEIFSQTEAQQLVAEELVEKWEKGKMRLLWDNKKRRNEALDCLVYAYAALRVSVQRWQLDLAVLAKSREEDT
TRPTLKELAAKLSGGVNGYSR

Specific function: Unknown

COG id: COG5525

COG function: function code R; Bacteriophage tail assembly protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To phage lambda terminase large subunit in the N- terminal section [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003458
- InterPro:   IPR008866 [H]

Pfam domain/function: PF02413 Caudo_TAP; PF05876 Terminase_GpA [H]

EC number: NA

Molecular weight: Translated: 75031; Mature: 75031

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRAQISVRGRGINYRIYSMNISEQQLNNMMSAVTTALQPLIRALPVTPVEWADQNYYLP
CCCCEEEEEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECC
KESSYGEGEWKTLPFQIAIMNSMGNDQIRTVNLIKSARVGYTKMLLGVAGYFIEHKSRNS
CCCCCCCCCCEECCEEEEEECCCCCCCEEEEHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
LLFQPTDSAAEDFMKSHVEATIRDVPCLKDLSPWLGRKHRDNTLTLKRFSSGVGFWCLGG
EEECCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCCCCCCEEEEEECCCCCCEEEECC
AAAKNYREKSVDVVCYDELSSFEPDVEKEGSPTLLGDKRIEGSVWPKSIRGSTPKIKGTC
HHHCCHHHCCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHCCCCCCCCEEE
QIEKAANESAHFMRFYVPCPHCGEELYLKFGDESTPFGLKWEKDSPESVFYLCEHHGCVI
EEECCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCEEECCCCCCCEEEEEECCCEEE
HQSELDQSNGRWICENTGMWTRDGLTFFSAADNEIPPPRSITFHIWTAYSPFTTWVQIVY
EHHHCCCCCCCEEECCCCCEEECCEEEEECCCCCCCCCCEEEEEEEECCCHHHHHHHHHH
DWLDALKDPNGLKTFVNTTLGETWEEAVGEKLDHQVLMDKVVRYTAAVPARVVYLTAGID
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCC
SQRNRFEMYVWGWAPGEEAFLVDKIIIMGRPDEEETLLRVDVAINKKYRHADGTEMTISR
CCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCEEHHH
VCWDTGGIDGEIVYQRSKKHGVFRVLPVKGASVYGKPVITMPKTRNQRGVYLCEVGTDTA
HHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEECCCCCCCCCEEEEECCCCHH
KEILYARMKAEPTPADEATSYAIRFPDDPEIFSQTEAQQLVAEELVEKWEKGKMRLLWDN
HHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
KKRRNEALDCLVYAYAALRVSVQRWQLDLAVLAKSREEDTTRPTLKELAAKLSGGVNGYS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCC
R
C
>Mature Secondary Structure
MQRAQISVRGRGINYRIYSMNISEQQLNNMMSAVTTALQPLIRALPVTPVEWADQNYYLP
CCCCEEEEEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECC
KESSYGEGEWKTLPFQIAIMNSMGNDQIRTVNLIKSARVGYTKMLLGVAGYFIEHKSRNS
CCCCCCCCCCEECCEEEEEECCCCCCCEEEEHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
LLFQPTDSAAEDFMKSHVEATIRDVPCLKDLSPWLGRKHRDNTLTLKRFSSGVGFWCLGG
EEECCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCCCCCCEEEEEECCCCCCEEEECC
AAAKNYREKSVDVVCYDELSSFEPDVEKEGSPTLLGDKRIEGSVWPKSIRGSTPKIKGTC
HHHCCHHHCCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHCCCCCCCCEEE
QIEKAANESAHFMRFYVPCPHCGEELYLKFGDESTPFGLKWEKDSPESVFYLCEHHGCVI
EEECCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCEEECCCCCCCEEEEEECCCEEE
HQSELDQSNGRWICENTGMWTRDGLTFFSAADNEIPPPRSITFHIWTAYSPFTTWVQIVY
EHHHCCCCCCCEEECCCCCEEECCEEEEECCCCCCCCCCEEEEEEEECCCHHHHHHHHHH
DWLDALKDPNGLKTFVNTTLGETWEEAVGEKLDHQVLMDKVVRYTAAVPARVVYLTAGID
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCC
SQRNRFEMYVWGWAPGEEAFLVDKIIIMGRPDEEETLLRVDVAINKKYRHADGTEMTISR
CCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCEEHHH
VCWDTGGIDGEIVYQRSKKHGVFRVLPVKGASVYGKPVITMPKTRNQRGVYLCEVGTDTA
HHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEECCCCCCCCCEEEEECCCCHH
KEILYARMKAEPTPADEATSYAIRFPDDPEIFSQTEAQQLVAEELVEKWEKGKMRLLWDN
HHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
KKRRNEALDCLVYAYAALRVSVQRWQLDLAVLAKSREEDTTRPTLKELAAKLSGGVNGYS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]