Click here to switch to the map view.

The map label for this gene is hcp

Identifier: 218688655

GI number: 218688655

Start: 868925

End: 870577

Strand: Reverse

Name: hcp

Synonym: ECED1_0840

Alternate gene names: 218688655

Gene position: 870577-868925 (Counterclockwise)

Preceding gene: 218688656

Following gene: 218688654

Centisome position: 16.71

GC content: 54.57

Gene sequence:

>1653_bases
ATGTTTTGTGTGCAATGTGAACAAACTATCCGTACTCCGGCAGGAAACGGCTGCTCATACGCGCAGGGGATGTGTGGTAA
AACGGCGGAAACCTCTGACCTTCAGGATTTACTCATCGCGGCGCTGCAAGGGCTTTCGGCCTGGGCAGTGAAAGCACGTG
AATACGGCATCATCAACCACGATGTAGACAGCTTTGCGCCACGTGCCTTTTTCTCAACCCTGACCAACGTTAACTTCGAT
TCTCCGCGTATTGTCGGCTACGCTCGTGAAGCGATTGCCCTGCGCGAGGCGCTGAAAGCACAATGCCTGGCTGTAGATGC
CAACGCCCGCGTCGATAACCCGATGGCTGACCTGCAACTGGTGAGCGACGATCTCGGCGAGCTGCAACGTCAGGCAGCAG
AATTTACCCCTAACAAAGATAAAGCGGCGATTGGCGAAAACATTCTCGGCCTGCGTCTACTGTGCCTGTATGGCCTGAAA
GGTGCGGCGGCCTATATGGAACACGCGCATGTTCTCGGTCAATACGACAACGATATTTATGCCCAGTACCATAAAATCAT
GGCGTGGCTGGGGACCTGGCCTGCCGATATGAACGCGCTTCTTGAGTGTTCAATGGAAATCGGCCAGATGAACTTCAAAG
TGATGAGCATTCTGGACGCAGGCGAAACCGGTAAATACGGTCACCCGACGCCAACTCAGGTCAACGTCAAAGCGACGGCG
GGTAAATGCATTCTGATTTCCGGTCACGATCTCAAAGATCTCTACAACCTGCTGGAACAGACCGAAGGCACGGGCGTTAA
TGTCTACACCCACGGCGAAATGCTGCCTGCGCATGGTTACCCGGAGCTGCGTAAATTCAAGCATCTGGTCGGTAACTACG
GCAGCGGCTGGCAGAATCAGCAAGTGGAGTTCGCTCGTTTCCCAGGCCCCATCGTGATGACCTCGAACTGCATCATCGAC
CCAACCGTAGGCGCTTATGACGATCGTATCTGGACCCGCAGCATCGTTGGCTGGCCGGGTGTGCGTCATCTGGATGGCGA
AGATTTCTCTGCAGTCATTGCCCAGGCGCAACAGATGGCGGGCTTCCCGTACAGCGAAATTCCGCACCTGATCACCGTGG
GCTTTGGTCGCCAGACACTGCTTGGCGCAGCCGATACGCTGATTGATCTGGTGAGCCGTGAAAAACTGCGTCATATCTTC
CTGCTTGGCGGCTGTGACGGCGCACGCGGCGAGCGTCACTATTTCACCGATTTCGCCACCAGCGTGCCGGATGACTGCCT
GATCCTGACCCTCGCTTGCGGTAAATATCGCTTTAATAAACTTGAGTTTGGCGATATCGAAGGTCTGCCGCGTCTGGTAG
ATGCTGGTCAATGTAACGATGCTTACTCAGCAATTATTCTGGCGGTAACGCTGGCAGAGAAACTGGGCTGCGGAGTCAAC
GATCTGCCGCTGTCGCTGGTGCTCTCCTGGTTTGAACAGAAAGCGATTGTCATTCTGCTGACGCTGCTTTCTCTGGGTGT
GAAAAATATCGTCACCGGCCCGACTGCACCTGGTTTCCTGACACCAGACCTGCTGGCGGTGCTGAACGAGAAATTCGGCC
TGCGTTCTATCACCACTGTTGAAGAAGACATGAAGCAACTGTTGAGCGCGTAA

Upstream 100 bases:

>100_bases
TCAATCTCCCTTAAAGTTGCATTAAAAATCTCTTTTATCCCCGCGTTAAGCGTCTTAACCTTAAACATGTATATTAAATA
TAACTTTAAAAGGTGTGATC

Downstream 100 bases:

>100_bases
GGAGTTTGTCGATGACGATGCCAACGAATCAATGCCCGTGGCGGATGCAGGTTCATCACATTACGCAAGAAACGCCGGAT
GTGTGGACGATTTCCCTGAT

Product: hydroxylamine reductase

Products: NA

Alternate protein names: Hybrid-cluster protein; HCP

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFD
SPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATA
GKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIID
PTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIF
LLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVN
DLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA

Sequences:

>Translated_550_residues
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFD
SPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATA
GKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIID
PTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIF
LLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVN
DLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
>Mature_550_residues
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFD
SPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATA
GKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIID
PTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIF
LLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVN
DLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA

Specific function: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O

COG id: COG1151

COG function: function code C; 6Fe-6S prismane cluster-containing protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HCP family

Homologues:

Organism=Escherichia coli, GI87081794, Length=550, Percent_Identity=99.6363636363636, Blast_Score=1137, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HCP_ECOK1 (A1A9B1)

Other databases:

- EMBL:   CP000468
- RefSeq:   YP_851965.1
- ProteinModelPortal:   A1A9B1
- SMR:   A1A9B1
- STRING:   A1A9B1
- EnsemblBacteria:   EBESCT00000035360
- GeneID:   4493314
- GenomeReviews:   CP000468_GR
- KEGG:   ecv:APECO1_1221
- eggNOG:   COG1151
- GeneTree:   EBGT00050000010298
- HOGENOM:   HBG294215
- OMA:   QEHIDMA
- ProtClustDB:   PRK05290
- BioCyc:   ECOL405955:APECO1_1221-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00069
- InterPro:   IPR010048
- InterPro:   IPR004137
- InterPro:   IPR011254
- InterPro:   IPR016099
- InterPro:   IPR016100
- Gene3D:   G3DSA:3.40.50.2030
- Gene3D:   G3DSA:1.20.1270.20
- PIRSF:   PIRSF000076
- TIGRFAMs:   TIGR01703

Pfam domain/function: PF03063 Prismane; SSF56821 Prismane_like

EC number: NA

Molecular weight: Translated: 60049; Mature: 60049

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINH
CEEEECHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
DVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQL
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHH
VSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIY
HHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHH
AQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEECC
GKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQ
CEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
QVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMA
CEEHEECCCCEEEECCEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFAT
CCCHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHH
SVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVN
CCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
DLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTV
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHH
EEDMKQLLSA
HHHHHHHHCC
>Mature Secondary Structure
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINH
CEEEECHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
DVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQL
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHH
VSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIY
HHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHH
AQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEECC
GKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQ
CEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
QVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMA
CEEHEECCCCEEEECCEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFAT
CCCHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHH
SVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVN
CCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
DLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTV
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHH
EEDMKQLLSA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA