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The map label for this gene is glnP

Identifier: 218688596

GI number: 218688596

Start: 804939

End: 805598

Strand: Reverse

Name: glnP

Synonym: ECED1_0775

Alternate gene names: 218688596

Gene position: 805598-804939 (Counterclockwise)

Preceding gene: 218688597

Following gene: 218688595

Centisome position: 15.46

GC content: 53.33

Gene sequence:

>660_bases
ATGCAGTTTGACTGGAGTGCCATCTGGCCTGCCATTCCGCTTCTGATTGAAGGTGCCAAAATGACCCTGTGGATTTCGGT
CCTCGGTCTGGCTGGCGGTCTGGTGATCGGATTGTTGGCAGGTTTTGCACGCACCTTCGGTGGTTGGATAGCCAACCACG
TCGCGCTGGTCTTTATTGAAGTGATCCGCGGCACACCTATCGTCGTCCAGGTGATGTTTATCTATTTCGCCCTGCCGATG
GCGTTTAACGATTTACGCATCGACCCGTTTACTGCGGCGGTGGTCACCATCATGATCAACTCCGGCGCGTACATTGCGGA
AATCACGCGTGGTGCGGTGCTGTCTATTCACAAAGGTTTTCGTGAAGCAGGACTGGCGCTCGGTCTTTCACGTTGGGAAA
CCATTCGCTACGTCATTTTACCGCTGGCACTGCGTCGTATGCTGCCGCCGCTGGGTAACCAGTGGATCATCAGCATTAAA
GACACTTCGCTGTTTATTGTTATCGGCGTGGCGGAACTGACCCGTCAGGGGCAAGAAATTATTGCCGGTAACTTCCGCGC
CCTTGAGATCTGGAGCGCCGTGGCGGTGTTCTATCTGATTATTACCCTGGTGCTGAGCTTTATTCTGCGTCGTCTGGAAA
GAAGGATGAAAATCCTGTGA

Upstream 100 bases:

>100_bases
CCCCGCCGGGGAGAGGATTAGGGTGAAGGGCGCAAACCCGCTCCGGGGCCATTAATTACCCTGAATTTGATTATTTACAC
CACGGTAACAGGAACAACAT

Downstream 100 bases:

>100_bases
TTGAATTTAAAAACGTCTCCAAGCATTTTGGTCCAACCCAGGTGCTGCACAATATCGATTTGAACATTGCTCAGGGCGAA
GTCGTGGTGATTATCGGGCC

Product: glutamine ABC transporter permease

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFARTFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPM
AFNDLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKIL

Sequences:

>Translated_219_residues
MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFARTFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPM
AFNDLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKIL
>Mature_219_residues
MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFARTFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPM
AFNDLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKIL

Specific function: Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787030, Length=219, Percent_Identity=100, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1788226, Length=207, Percent_Identity=36.231884057971, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786873, Length=227, Percent_Identity=30.8370044052863, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788646, Length=214, Percent_Identity=27.1028037383178, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788645, Length=206, Percent_Identity=30.5825242718447, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787087, Length=223, Percent_Identity=27.3542600896861, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI87082239, Length=204, Percent_Identity=32.3529411764706, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786874, Length=213, Percent_Identity=23.4741784037559, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1787086, Length=213, Percent_Identity=26.2910798122066, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994930, Length=134, Percent_Identity=31.3432835820896, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLNP_ECO57 (P0AEQ8)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B85590
- PIR:   H90739
- RefSeq:   NP_286574.1
- RefSeq:   NP_308915.1
- ProteinModelPortal:   P0AEQ8
- SMR:   P0AEQ8
- EnsemblBacteria:   EBESCT00000024555
- EnsemblBacteria:   EBESCT00000057768
- GeneID:   917627
- GeneID:   958053
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z1032
- KEGG:   ecs:ECs0888
- GeneTree:   EBGT00050000008884
- HOGENOM:   HBG704821
- OMA:   WFSSRIS
- ProtClustDB:   PRK09494
- BioCyc:   ECOL83334:ECS0888-MONOMER
- InterPro:   IPR010065
- InterPro:   IPR000515
- TIGRFAMs:   TIGR01726

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 24365; Mature: 24365

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f675110)-; HASH(0x1f886a58)-; HASH(0x1f43d050)-; HASH(0x1edd71f0)-; HASH(0x1f334a60)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFARTFGGWIANHVALVFIE
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGF
HHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEHHHCCHHHHHHHHH
REAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIKDTSLFIVIGVAELTRQGQEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEEEHHHHHHCCHHH
IAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKIL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFARTFGGWIANHVALVFIE
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGF
HHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEHHHCCHHHHHHHHH
REAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIKDTSLFIVIGVAELTRQGQEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEEEHHHHHHCCHHH
IAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKIL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796