Click here to switch to the map view.

The map label for this gene is speF [H]

Identifier: 218688497

GI number: 218688497

Start: 695775

End: 697973

Strand: Reverse

Name: speF [H]

Synonym: ECED1_0672

Alternate gene names: 218688497

Gene position: 697973-695775 (Counterclockwise)

Preceding gene: 218688498

Following gene: 218688496

Centisome position: 13.4

GC content: 49.11

Gene sequence:

>2199_bases
ATGTCAGAATTAAAAATTGCCGTTAGCCGTTCTTGCCCGGATTGTTTTTCCACTCATCGTGAATGCGTGAATATTGACAA
AAGTAATTATATTGACGTTGCCGCCATTATTTTATCAGTCAATGATGTTGAACATGGAAAACTCGATGAAATAGACGCTA
CTGGCTATGGCATTCCTGTTTTTATTGCAACGGAAAATGAAGAACGTGTACCAGCAGAATATCTGCCACGTATTTCTGGT
GTCTTCGAGCATTGCGAATCACGGAAAGAGTTTTATGGACGTCAGTTAGAAACCGCTGCCAGCCATTATGAAACGCAACT
GCGCCCGCCCTTCTTCCGCGCACTGGTCGATTATGTCAATCAGGGCAATAGCGCTTTTGACTGCCCGGGTCATCAGGGAG
GTGAGTTTTTCCGTCGCCATCCGGCAGGCAATCAGTTCGTGGAATATTTTGGCGAAATGCTCTTCCGCTCCGACTTGTGT
AATGCCGACGTTGCAATGGGCGATCTACTGATTCATGAAGGTGCGCCATGCATTGCACAGCAACATGCGGCTAAAGTGTT
TAATGCCGATAAAACGTACTTTGTTTTAAACGGCACCTCCTCTTCCAACAAAGTGGTTTTAAACGCCCTGCTGACACCGG
GTGATCTGGTGCTGTTTGACCGCAATAACCATAAGTCTAACCACCACGGGGCCTTGCTACAGGCTGGTGCAACACCGGTG
TATCTGGAAACAGCACGTAACCCGTATGGTTTTATCGGTGGCATTGATGCGCACTGCTTCGAAGAAAGTTATCTGCGTGA
ACTGATTACAGAAGTTGCACCGCAACGGGCAAAAGAGGCGCGTCCGTTCCGCCTCGCTGTGATTCAGTTAGGCACCTACG
ACGGTACTATTTATAACGCCCGCCAGGTGGTGGATAAAATCGGTCATCTGTGTGACTACATCCTGTTTGACTCAGCATGG
GTCGGCTATGAACAGTTTATTCCGATGATGGCGGACTGTTCGCCGCTGCTACTGGAGCTTAATGAGAACGATCCGGGTAT
TCTGGTTACGCAATCTGTGCATAAACAACAGGCTGGTTTTTCTCAGACTTCACAAATTCATAAAAAAGACAGCCATATCA
AAGGGCAACAGCGTTATGTACCGCACAAACGCATGAACAACGCCTTTATGATGCACGCCTCCACCAGCCCGTTCTATCCG
CTGTTTGCCGCACTGGATATCAACGCCAAAATGCATGAAGGTGTCAGCGGTCGTAATATGTGGATGGATTGTGTGGTTAA
CGGTATTAATGCCCGCAAATTGATCCTCGATAACTGCCAGCACATTCGCCCGTTCGTTCCTGAACTGGTGGATGGTAAAC
CCTGGCAGTCGTATGAAACAGCGCAAATTGCGGTTGATCTGCGCTTCTTTAAATTTGTACCCGGTGAGCACTGGCATTCT
TTTGAAGGCTACGCAGAGAACCAATACTTTGTCGATCCGTGCAAACTGTTGCTGACAACTCCAGGTATTGATGCACGTAA
CGGCGAATATGAAGCGTTCGGTGTACCCGCAACGATTCTTGCTAACTTCCTGCGCGAAAATGGCGTAGTGCCGGAAAAAT
GCGATCTTAACTCCATCCTCTTCCTGCTGACTCCGGCAGAAGATATGGCCAAACTGCAGCAACTTGTTGCCCTGCTGGTA
CGCTTCGAAAAACTACTGGAAGCTGATGCGCCCCTGGCGGAAGTACTGCCTTCCATCTACAAACAGCATGAAGAGCGCTA
CGCCGGTTATACCCTTCGTCAGTTGTGCCAGGAAATGCATGATTTGTATGCCCGCCACAACGTGAAACAACTGCAAAAAG
AGATGTTCCGTAAGGAACACTTCCCACGCGTCAGCATGAATCCGCAAGAAGCCAACTACGCCTACTTACGCGGTGAAGTG
GAGCTGGTTCGTCTGCCGGATGCAGAAGGCCGTATCGCTGCCGAAGGTGCGCTTCCTTATCCTCCGGGTGTGCTGTGTGT
TGTTCCTGGTGAAATCTGGGGTGGTGCTGTTCTGCGTTACTTCAGCGCTCTGGAAGAAGGCATCAACCTGCTGCCAGGTT
TTGCACCGGAGCTGCAGGGTGTCTATATCGAAGAACATGATGGTCGTAAGCAAGTTTGGTGCTATGTCATCAAGCCTCGT
GATGCGCAAAGCGCCCTGTTGAAAGGGGAAAAATTATGA

Upstream 100 bases:

>100_bases
TTATTTATCAGCGGTGGGGTTTTGCTTTTTTCCGGCGTGATCAATTTCTCCTTTGAGAAATTGAGGACCTGCTATTACCT
GAAATAAAGAGATGAACAAA

Downstream 100 bases:

>100_bases
GTCAGGCGAAATCGAACAAAATGGGTGTCGTTCAGTTAACCATACTGACGATGGTCAACATGATGGGCTCCGGTATCATC
ATGCTGCCGACAAAGCTTGC

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 731

Protein sequence:

>732_residues
MSELKIAVSRSCPDCFSTHRECVNIDKSNYIDVAAIILSVNDVEHGKLDEIDATGYGIPVFIATENEERVPAEYLPRISG
VFEHCESRKEFYGRQLETAASHYETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLC
NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
YLETARNPYGFIGGIDAHCFEESYLRELITEVAPQRAKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW
VGYEQFIPMMADCSPLLLELNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYP
LFAALDINAKMHEGVSGRNMWMDCVVNGINARKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFKFVPGEHWHS
FEGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLV
RFEKLLEADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEV
ELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
DAQSALLKGEKL

Sequences:

>Translated_732_residues
MSELKIAVSRSCPDCFSTHRECVNIDKSNYIDVAAIILSVNDVEHGKLDEIDATGYGIPVFIATENEERVPAEYLPRISG
VFEHCESRKEFYGRQLETAASHYETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLC
NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
YLETARNPYGFIGGIDAHCFEESYLRELITEVAPQRAKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW
VGYEQFIPMMADCSPLLLELNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYP
LFAALDINAKMHEGVSGRNMWMDCVVNGINARKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFKFVPGEHWHS
FEGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLV
RFEKLLEADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEV
ELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
DAQSALLKGEKL
>Mature_731_residues
SELKIAVSRSCPDCFSTHRECVNIDKSNYIDVAAIILSVNDVEHGKLDEIDATGYGIPVFIATENEERVPAEYLPRISGV
FEHCESRKEFYGRQLETAASHYETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLCN
ADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPVY
LETARNPYGFIGGIDAHCFEESYLRELITEVAPQRAKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAWV
GYEQFIPMMADCSPLLLELNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYPL
FAALDINAKMHEGVSGRNMWMDCVVNGINARKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFKFVPGEHWHSF
EGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLVR
FEKLLEADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEVE
LVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPRD
AQSALLKGEKL

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786909, Length=732, Percent_Identity=96.5846994535519, Blast_Score=1482, Evalue=0.0,
Organism=Escherichia coli, GI87082193, Length=719, Percent_Identity=67.3157162726008, Blast_Score=1020, Evalue=0.0,
Organism=Escherichia coli, GI221142684, Length=737, Percent_Identity=31.3432835820896, Blast_Score=345, Evalue=6e-96,
Organism=Escherichia coli, GI1790573, Length=636, Percent_Identity=33.4905660377358, Blast_Score=314, Evalue=1e-86,
Organism=Escherichia coli, GI1786384, Length=657, Percent_Identity=32.1156773211568, Blast_Score=302, Evalue=4e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 82531; Mature: 82400

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELKIAVSRSCPDCFSTHRECVNIDKSNYIDVAAIILSVNDVEHGKLDEIDATGYGIPV
CCCCEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEE
FIATENEERVPAEYLPRISGVFEHCESRKEFYGRQLETAASHYETQLRPPFFRALVDYVN
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLCNADVAMGDLLIHEGAPCIAQ
CCCCEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCCHHHH
QHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
HHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPYGFIGGIDAHCFEESYLRELITEVAPQRAKEARPFRLAVIQLGTYDGTIYNA
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEEEEEECCCCCCHHH
RQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCSPLLLELNENDPGILVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHCCC
SQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYPLFAALDINAKMHEGVSGRNM
HHHHHHHHHHHCCCCCHHCCCHHHCCCEEEEEECCCCCCEEEEEEECCCHHHCCCCCCCH
WMDCVVNGINARKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFKFVPGEHWHS
HHHHHHCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCC
FEGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSIL
CCCCCCCCEEECCHHEEEECCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAEDMAKLQQLVALLVRFEKLLEADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMH
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPY
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCEEECCCCCC
PPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEEEEECCC
DAQSALLKGEKL
CHHHHHHCCCCC
>Mature Secondary Structure 
SELKIAVSRSCPDCFSTHRECVNIDKSNYIDVAAIILSVNDVEHGKLDEIDATGYGIPV
CCCEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEE
FIATENEERVPAEYLPRISGVFEHCESRKEFYGRQLETAASHYETQLRPPFFRALVDYVN
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLCNADVAMGDLLIHEGAPCIAQ
CCCCEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCCHHHH
QHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
HHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPYGFIGGIDAHCFEESYLRELITEVAPQRAKEARPFRLAVIQLGTYDGTIYNA
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEEEEEECCCCCCHHH
RQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCSPLLLELNENDPGILVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHCCC
SQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYPLFAALDINAKMHEGVSGRNM
HHHHHHHHHHHCCCCCHHCCCHHHCCCEEEEEECCCCCCEEEEEEECCCHHHCCCCCCCH
WMDCVVNGINARKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFKFVPGEHWHS
HHHHHHCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCC
FEGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSIL
CCCCCCCCEEECCHHEEEECCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAEDMAKLQQLVALLVRFEKLLEADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMH
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPY
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCEEECCCCCC
PPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEEEEECCC
DAQSALLKGEKL
CHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1939141; 8905232; 9278503 [H]