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The map label for this gene is fepD [H]

Identifier: 218688416

GI number: 218688416

Start: 610011

End: 611015

Strand: Reverse

Name: fepD [H]

Synonym: ECED1_0587

Alternate gene names: 218688416

Gene position: 611015-610011 (Counterclockwise)

Preceding gene: 218688418

Following gene: 218688415

Centisome position: 11.73

GC content: 60.5

Gene sequence:

>1005_bases
ATGTCTGGTTCTGTTGCCGTGACACGCGCCATTGCCGTGCCCGGATTGCTGTTATTACTGATTATCGCGACGGCATTAAG
CCTACTCATTGGGGCAAAATCACTCCCCGCCTCCGTAGTGCTGGAGGCGCTCTCCGGCACCTGCCAGAGCGCCTCCAGCA
CCATTGTGCTCGACGCCCGTCTGCCGCGCACCCTTGCCGGTTTACTGGCAGGCGGTGCGCTTGGCCTTGCCGGGGCGTTA
ATGCAAACCCTCACCCGAAACCCGCTTGCCGATCCTGGTTTGCTTGGCGTGAACGCCGGTGCCAGTTTTGCCATTGTGCT
GGGCGCGGCGCTGTTTGGTTACTCTTCCGCGCAGGAGCAACTGGCGATGGCCTTCGCCGGGGCGCTGGTGGCCTCGTTGA
TTGTTGCCTTTACCGGCAGCCAGGGCGGCGGGCAGTTAAGTCCGGTGCGTTTAACCCTAGCGGGCGTGGCGCTGGCGGCG
GTGCTGGAAGGGCTGACCAGCGGCATCGCCCTGCTTAATCCCGACGTCTACGATCAACTGCGTTTCTGGCAAGCCGGTTC
GCTGGATATTCGCAATCTACATACCTTAAAAGTGGTGCTAATCCCGGTGCTTACCGCTGGAGCAACTGCGCTATTACTGA
GCCGCGCGCTGAACAGTTTAAGCCTTGGCAGTGACACCGCGACGGCACTGGGCAGTCGCGTAGCGCGCACACAGTTGATT
GGTCTGCTGGCAATTACCGTGCTTTGTGGTAGTGCGACGGCGGTAGTTGGCCCGATTGCCTTTATTGGCCTGATGATGCC
GCACATGGCGCGCTGGCTGGTAGGTGCCGATCATCGCTGGTCGCTGCCCGTCACGCTACTCGCTACCCCTGCCCTGCTGC
TGTTTGCCGATATCATTGGGCGGGTGATTGTTCCCGGCGAACTGCGCGTTTCTGTAGTCAGTGCCTTTATTGGCGCACCA
GTGCTGATCTTCCTCGTACGACGTAAAACGCGAGGTGGCGCATGA

Upstream 100 bases:

>100_bases
TGCCATCAAATATTTTAAATACCTATTCTTAGGCTGCACATGCTAACATATCCAAATAAGATCGATAACGATAATTAATT
TCATTATCATGGAAGTTCGT

Downstream 100 bases:

>100_bases
TTTACGTCTCTCGCCGATTAATTATCACCTGTCTGCTGTTGCTAATAGCTTGTGTGATGGCAGGCGTGTGGGGATTACGT
AGCGGTGCCGTCACGCTGGA

Product: iron-enterobactin transporter membrane protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEALSGTCQSASSTIVLDARLPRTLAGLLAGGALGLAGAL
MQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLTAGATALLLSRALNSLSLGSDTATALGSRVARTQLI
GLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAP
VLIFLVRRKTRGGA

Sequences:

>Translated_334_residues
MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEALSGTCQSASSTIVLDARLPRTLAGLLAGGALGLAGAL
MQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLTAGATALLLSRALNSLSLGSDTATALGSRVARTQLI
GLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAP
VLIFLVRRKTRGGA
>Mature_333_residues
SGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEALSGTCQSASSTIVLDARLPRTLAGLLAGGALGLAGALM
QTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAAV
LEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLTAGATALLLSRALNSLSLGSDTATALGSRVARTQLIG
LLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPV
LIFLVRRKTRGGA

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=334, Percent_Identity=98.5029940119761, Blast_Score=620, Evalue=1e-179,
Organism=Escherichia coli, GI1790741, Length=288, Percent_Identity=38.8888888888889, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790740, Length=305, Percent_Identity=36.3934426229508, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786804, Length=337, Percent_Identity=34.7181008902077, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786347, Length=277, Percent_Identity=35.3790613718412, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=39.1003460207612, Blast_Score=111, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33768; Mature: 33636

Theoretical pI: Translated: 11.25; Mature: 11.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEALSGTCQSASSTIVLDAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECC
LPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHCCCHHHHH
LAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLTSGIALLNPDVYDQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHH
RFWQAGSLDIRNLHTLKVVLIPVLTAGATALLLSRALNSLSLGSDTATALGSRVARTQLI
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
HEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEALSGTCQSASSTIVLDAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECC
LPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHCCCHHHHH
LAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLTSGIALLNPDVYDQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHH
RFWQAGSLDIRNLHTLKVVLIPVLTAGATALLLSRALNSLSLGSDTATALGSRVARTQLI
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
HEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 1787794; 9278503 [H]