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The map label for this gene is tauC [H]

Identifier: 218688234

GI number: 218688234

Start: 412356

End: 413183

Strand: Direct

Name: tauC [H]

Synonym: ECED1_0394

Alternate gene names: 218688234

Gene position: 412356-413183 (Clockwise)

Preceding gene: 218688233

Following gene: 218688235

Centisome position: 7.92

GC content: 58.7

Gene sequence:

>828_bases
ATGAGTGTGCTCATTAATGAAAAACTGCATTCGCATCGGCTGAAATGGCGCTGGCCGCTCTCGCGTCAGGTGACCTTAAG
CATTGGCACGTTAGCGATTTTACTCACTGTATGGTGGGTAGTCGCGGCGCTGCAACTGATTAGCCCGCTGTTTTTGCCGC
CACCGCAACAGGTACTGGCAAAACTGCTCACCATTGCCGGGCCGCAGGGATTTATGGACGCCACGCTGTGGCAGCATCTG
GCAGCCAGCCTGACGCGCATTGTGCTGGCGCTACTCGCGGCGGTGTTGATCGGTATTCCGGTCGGGATCGCCATGGGGCT
AAGCCCGACGGTGCGCGGCATTCTGGATCCGATAATCGAGCTTTATCGTCCGGTGCCGCCGCTGGCTTATTTGCCGCTGA
TGGTGATCTGGTTTGGTATTGGCGAAACCTCGAAGATCTTACTGATCTATCTAGCGATTTTTGCGCCGGTGGCGATGTCG
GCGCTGGCGGGGGTGAAAAGCGCGCAGCAGGTTCGCATTCGTGCCGCCCAGTCGCTGGGTGCCAGCCGTGCGCAGGTGCT
GTGGTTTGTCATTTTGCCCGGCGCGCTGCCGGAAATCCTCACCGGATTACGCATTGGTCTGGGTGTGGGCTGGTCTACGC
TGGTGGCGGCGGAGCTGATTGCCGCAACGCGCGGTTTAGGATTTATGGTTCAGTCAGCGGGTGAATTTCTCGCGACTGAC
GTGGTGCTGGCGGGGATCGCGGTGATTGCGATTATCGCCTTTCTTTTAGAACTGGGTCTGCGCGCGTTACAGCGCCGCCT
GACGCCCTGGCATGGAGAAGTACAATGA

Upstream 100 bases:

>100_bases
TTGCGGGAGAGTCGAGCCGCAGCATCAAGTCCGATCCACAATTCATCGCCATGCGCGAATATGTTTTAAGCCGCGTATTT
GAGCAACGGGAGGCGTTCTC

Downstream 100 bases:

>100_bases
GTGAACGTCTGAGCATTACCCCGCTGGGGCCGTATATTGGCGCACAAATTACGGGGGCCGACTTAACGCGCCCGTTAAGC
GATAATCAGTTTGAACAGCT

Product: taurine transporter subunit

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSVLINEKLHSHRLKWRWPLSRQVTLSIGTLAILLTVWWVVAALQLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHL
AASLTRIVLALLAAVLIGIPVGIAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ

Sequences:

>Translated_275_residues
MSVLINEKLHSHRLKWRWPLSRQVTLSIGTLAILLTVWWVVAALQLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHL
AASLTRIVLALLAAVLIGIPVGIAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ
>Mature_274_residues
SVLINEKLHSHRLKWRWPLSRQVTLSIGTLAILLTVWWVVAALQLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHLA
ASLTRIVLALLAAVLIGIPVGIAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSA
LAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDV
VLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ

Specific function: Part of a binding-protein-dependent transport system for taurine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=275, Percent_Identity=96.7272727272727, Blast_Score=490, Evalue=1e-140,
Organism=Escherichia coli, GI87081802, Length=238, Percent_Identity=34.453781512605, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1789033, Length=172, Percent_Identity=30.8139534883721, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29589; Mature: 29458

Theoretical pI: Translated: 11.19; Mature: 11.19

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLINEKLHSHRLKWRWPLSRQVTLSIGTLAILLTVWWVVAALQLISPLFLPPPQQVLA
CCCEECCHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
KLLTIAGPQGFMDATLWQHLAASLTRIVLALLAAVLIGIPVGIAMGLSPTVRGILDPIIE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAAQSLG
HHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
CHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SVLINEKLHSHRLKWRWPLSRQVTLSIGTLAILLTVWWVVAALQLISPLFLPPPQQVLA
CCEECCHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
KLLTIAGPQGFMDATLWQHLAASLTRIVLALLAAVLIGIPVGIAMGLSPTVRGILDPIIE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAAQSLG
HHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
CHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503 [H]