Click here to switch to the map view.

The map label for this gene is fhuA [H]

Identifier: 218688027

GI number: 218688027

Start: 173383

End: 175641

Strand: Direct

Name: fhuA [H]

Synonym: ECED1_0156

Alternate gene names: 218688027

Gene position: 173383-175641 (Clockwise)

Preceding gene: 218688026

Following gene: 218688028

Centisome position: 3.33

GC content: 50.91

Gene sequence:

>2259_bases
ATGGCACCTTCCAAAACTGCTCAGCCAAAACACTCACTGCGTAAAATCGCAGTTGTAGTAGCCACAGCGGTTAGCGGCAT
GTCTGTTTATGCACAGGCAGCGGTTGAACCGAAAGAAGACACTATCACCGTTACCGCTGCACCTGCGCCGCAAGAAAGCG
CATGGGGGCCGGCTGCAACTATTGCGGCGCGACAGTCAGCTACCGGCACTAAAACCGATACGCCGATTCAAAAAGTACCT
CAATCTATTTCTGTCGTCACCGCTGAAGAGATGGCGCTGCATCAGCCTAAGTCGGTGAAAGAAGCGCTTAGCTATACCCC
TGGCGTTGCTGTGGGAACCCGTGGCGCATCTAATACTTATGATTACCTGATCATCCGCGGATTTGCGGCAGACGGCCAAA
GCCAGAATAACTATCTGAATGGCCTGAAGTTGCAGGGCAACTTCTATAACGATGCGGTCATCGACCCGTATATGCTGGAA
CGTGCTGAAATTATGCGTGGCCCGGTTTCCGTGCTTTACGGTAAAAGCAGTCCTGGCGGTCTGTTGAATATGGTCAGCAA
GCGTCCGACCACTGAACCGTTGAAAGAAGTTCAGTTTAAGGCCGGGACTGACAGCCTGTTCCAGACCGGTTTTGACTTCA
GCGATGCACTGGATGATGACGGCGTTTATTCTTATCGCCTGACCGGTCTTGCGCGTTCTGCCAATGCCCAGCAGAAAGGG
TCAGAAGAGCAGCGTTATGCTATTGCACCGGCGTTCACCTGGCGTCCGGACGATAAAACCAATTTCACCTTCCTTTCTTA
CTTCCAGAACGAGCCGGAAACTGGTTATTACGGCTGGCTGCCGAAAGAGGGGACCGTTGAGCCGCTGCCAAACGGTAAGC
GTCTGCCGACAGACTTTAACGAAGGGGCGAAGAACAACACCTATTCTCGTAACGAGAAGATGATTGGTTATAGCTTCGAC
CACGAATTTAACGACACCTTTACTGTGCGTCAGAACCTGCGCTTTGCGCAAAATAAAGTTTCGCAAAAGAGCGTATATGG
CTACGGTATGTGTTCAGATCCGCTGTATACCAAAGACCAGGAGGCACTCAAGGCGAGTCCATGTTTAAGTATCCCGCAGT
CTCAATGGGGCCATACACTGACTCGTCAGTACGTTATCGATAATGAGAAGTTAGAAAACTTCTCTGTTGATACTCAGTTG
CAAAGCAAATTCGCAACCGGTTCTGTGGATCACACTCTGCTGACTGGCGTTGACTTTATGCGTATGCGTAATGACATCGA
CTCCTGGTTCGGATATGCCGGTTCAGTTGCACCATCTGATATCTATAATTTAGACCGTAGTGACTTTGATTTTGGCGCTC
ACCCGAATCCGTCTGGTCCATACCGCGTTCTGCTGAAACAGAAACAAACCGGCCTGTATGTTCAGGATCAGGCGCAGTGG
GATAAAGTGCTGGTTACGCTTGGCGGTCGCTATGACTGGGCCGATCAGTCATCTTTCAACCGTGATTACGGTAATAAATC
TGAACGTGACGACAAAGAGTTCACCTGGCGTGGTGGTGTAAACTACCTGTTCGACAACGGCGTAACGCCTTACTTCAGCT
ACAGTGAATCATTTGAACCCGCTTCACAGACTGATGCGAACGGTGATCTGTTTGCACCTTCGAAAGGCAAACAGTATGAA
GTCGGCGTGAAATATGTGCCAGAAGATCGCCCAATTGTGGTGACTGGCGCACTGTATCAGCTTACCAAAACTAATAACCT
GATGGCGGATCCGAACGGTTCACTGTTCTCGGTTGAAGGCGGTGAGATTCGTGCGCGTGGCGTAGAGCTGGAAGCGAAAG
CGGCACTGTCGGCGAGTGTTAACGTAGTCGGTTCTTATACTTACACCGATGCGGAATACACTACCGATACTACCTACAAA
GGCAATACGCCTGCACAGGTGCCAAAACACATGGCTTCGCTGTGGGCTGACTATACCTTCTTTGACGGTCCGCTTTCAGG
TCTGACGCTGGGCACCGGTGGTCGTTATACTGGCTCCAGCTATGGTGATCCGGCTAACTCCTTTAAAGTGGGAAGTTATA
CGGTCGTGGATGCGTTAGTGCGTTATGATCTGGCGCGAGTCGGCATGGCGGGCTCCAACGTGGCGCTGCATGTCAACAAC
CTGTTTGATCGTGAATACGTCGCCAGCTGCTTTAACACTTATGGTTGCTTCTGGGGCGCAGAACGTCAGGTCGTTGCAAC
CGCAACCTTCCGTTTCTAA

Upstream 100 bases:

>100_bases
CGTACCGCTTGCGAACCCGCCAGCGTTTCGAATATTATCTCATCTTTGTAATAATCATTCTCGTTTACGTTATCATTCAC
TTTACACCAGAGAAATACCA

Downstream 100 bases:

>100_bases
TTTCTCTTTTGGGGCACGGATTTCCGTGCCCGTTTCACAAGTTGGCTGTTATGCAGGAATACACGAATCATTCCGATACC
ACTTTTGCACTGCGTAATAT

Product: ferrichrome outer membrane transporter

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 752; Mature: 751

Protein sequence:

>752_residues
MAPSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVP
QSISVVTAEEMALHQPKSVKEALSYTPGVAVGTRGASNTYDYLIIRGFAADGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDALDDDGVYSYRLTGLARSANAQQKG
SEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMIGYSFD
HEFNDTFTVRQNLRFAQNKVSQKSVYGYGMCSDPLYTKDQEALKASPCLSIPQSQWGHTLTRQYVIDNEKLENFSVDTQL
QSKFATGSVDHTLLTGVDFMRMRNDIDSWFGYAGSVAPSDIYNLDRSDFDFGAHPNPSGPYRVLLKQKQTGLYVQDQAQW
DKVLVTLGGRYDWADQSSFNRDYGNKSERDDKEFTWRGGVNYLFDNGVTPYFSYSESFEPASQTDANGDLFAPSKGKQYE
VGVKYVPEDRPIVVTGALYQLTKTNNLMADPNGSLFSVEGGEIRARGVELEAKAALSASVNVVGSYTYTDAEYTTDTTYK
GNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANSFKVGSYTVVDALVRYDLARVGMAGSNVALHVNN
LFDREYVASCFNTYGCFWGAERQVVATATFRF

Sequences:

>Translated_752_residues
MAPSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVP
QSISVVTAEEMALHQPKSVKEALSYTPGVAVGTRGASNTYDYLIIRGFAADGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDALDDDGVYSYRLTGLARSANAQQKG
SEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMIGYSFD
HEFNDTFTVRQNLRFAQNKVSQKSVYGYGMCSDPLYTKDQEALKASPCLSIPQSQWGHTLTRQYVIDNEKLENFSVDTQL
QSKFATGSVDHTLLTGVDFMRMRNDIDSWFGYAGSVAPSDIYNLDRSDFDFGAHPNPSGPYRVLLKQKQTGLYVQDQAQW
DKVLVTLGGRYDWADQSSFNRDYGNKSERDDKEFTWRGGVNYLFDNGVTPYFSYSESFEPASQTDANGDLFAPSKGKQYE
VGVKYVPEDRPIVVTGALYQLTKTNNLMADPNGSLFSVEGGEIRARGVELEAKAALSASVNVVGSYTYTDAEYTTDTTYK
GNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANSFKVGSYTVVDALVRYDLARVGMAGSNVALHVNN
LFDREYVASCFNTYGCFWGAERQVVATATFRF
>Mature_751_residues
APSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQ
SISVVTAEEMALHQPKSVKEALSYTPGVAVGTRGASNTYDYLIIRGFAADGQSQNNYLNGLKLQGNFYNDAVIDPYMLER
AEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDALDDDGVYSYRLTGLARSANAQQKGS
EEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMIGYSFDH
EFNDTFTVRQNLRFAQNKVSQKSVYGYGMCSDPLYTKDQEALKASPCLSIPQSQWGHTLTRQYVIDNEKLENFSVDTQLQ
SKFATGSVDHTLLTGVDFMRMRNDIDSWFGYAGSVAPSDIYNLDRSDFDFGAHPNPSGPYRVLLKQKQTGLYVQDQAQWD
KVLVTLGGRYDWADQSSFNRDYGNKSERDDKEFTWRGGVNYLFDNGVTPYFSYSESFEPASQTDANGDLFAPSKGKQYEV
GVKYVPEDRPIVVTGALYQLTKTNNLMADPNGSLFSVEGGEIRARGVELEAKAALSASVNVVGSYTYTDAEYTTDTTYKG
NTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANSFKVGSYTVVDALVRYDLARVGMAGSNVALHVNNL
FDREYVASCFNTYGCFWGAERQVVATATFRF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=753, Percent_Identity=89.2430278884462, Blast_Score=1361, Evalue=0.0,
Organism=Escherichia coli, GI1787024, Length=804, Percent_Identity=24.5024875621891, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1787344, Length=783, Percent_Identity=22.8607918263091, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 82836; Mature: 82704

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00430 TONB_DEPENDENT_REC_1 ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAAT
CCCCCCCCHHHHHHHHHHHHHHHHCCHHEEEHCCCCCCCCEEEEEECCCCCCCCCCCHHH
IAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEALSYTPGVAVGTRGASNTY
HEECCCCCCCCCCCCHHHCCCHHEEEEHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCE
DYLIIRGFAADGQSQNNYLNGLKLQGNFYNDAVIDPYMLERAEIMRGPVSVLYGKSSPGG
EEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCH
LLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDALDDDGVYSYRLTGLARSANAQQKG
HHHHHHCCCCCCHHHHHEECCCCHHHHHCCCCHHHCCCCCCEEEEEEECHHHCCCCHHCC
SEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFN
CCCCEEEEEEEEEECCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
EGAKNNTYSRNEKMIGYSFDHEFNDTFTVRQNLRFAQNKVSQKSVYGYGMCSDPLYTKDQ
CCCCCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHEEECCCCCCCCCCCCH
EALKASPCLSIPQSQWGHTLTRQYVIDNEKLENFSVDTQLQSKFATGSVDHTLLTGVDFM
HHHHCCCCCCCCHHHHCCHHHHEEEECCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHH
RMRNDIDSWFGYAGSVAPSDIYNLDRSDFDFGAHPNPSGPYRVLLKQKQTGLYVQDQAQW
HHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCC
DKVLVTLGGRYDWADQSSFNRDYGNKSERDDKEFTWRGGVNYLFDNGVTPYFSYSESFEP
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCCCCCC
ASQTDANGDLFAPSKGKQYEVGVKYVPEDRPIVVTGALYQLTKTNNLMADPNGSLFSVEG
CCCCCCCCCEECCCCCCEEEECEEECCCCCCEEEECCEEEEECCCCEEECCCCCEEEECC
GEIRARGVELEAKAALSASVNVVGSYTYTDAEYTTDTTYKGNTPAQVPKHMASLWADYTF
CEEEEECEEEEHHHHHEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEE
FDGPLSGLTLGTGGRYTGSSYGDPANSFKVGSYTVVDALVRYDLARVGMAGSNVALHVNN
ECCCCCCEEECCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
LFDREYVASCFNTYGCFWGAERQVVATATFRF
HHHHHHHHHHHHHHHHEECCCCEEEEEEEECC
>Mature Secondary Structure 
APSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITVTAAPAPQESAWGPAAT
CCCCCCCHHHHHHHHHHHHHHHHCCHHEEEHCCCCCCCCEEEEEECCCCCCCCCCCHHH
IAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEALSYTPGVAVGTRGASNTY
HEECCCCCCCCCCCCHHHCCCHHEEEEHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCE
DYLIIRGFAADGQSQNNYLNGLKLQGNFYNDAVIDPYMLERAEIMRGPVSVLYGKSSPGG
EEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCH
LLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDALDDDGVYSYRLTGLARSANAQQKG
HHHHHHCCCCCCHHHHHEECCCCHHHHHCCCCHHHCCCCCCEEEEEEECHHHCCCCHHCC
SEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFN
CCCCEEEEEEEEEECCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
EGAKNNTYSRNEKMIGYSFDHEFNDTFTVRQNLRFAQNKVSQKSVYGYGMCSDPLYTKDQ
CCCCCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHEEECCCCCCCCCCCCH
EALKASPCLSIPQSQWGHTLTRQYVIDNEKLENFSVDTQLQSKFATGSVDHTLLTGVDFM
HHHHCCCCCCCCHHHHCCHHHHEEEECCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHH
RMRNDIDSWFGYAGSVAPSDIYNLDRSDFDFGAHPNPSGPYRVLLKQKQTGLYVQDQAQW
HHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCC
DKVLVTLGGRYDWADQSSFNRDYGNKSERDDKEFTWRGGVNYLFDNGVTPYFSYSESFEP
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCCCCCC
ASQTDANGDLFAPSKGKQYEVGVKYVPEDRPIVVTGALYQLTKTNNLMADPNGSLFSVEG
CCCCCCCCCEECCCCCCEEEECEEECCCCCCEEEECCEEEEECCCCEEECCCCCEEEECC
GEIRARGVELEAKAALSASVNVVGSYTYTDAEYTTDTTYKGNTPAQVPKHMASLWADYTF
CEEEEECEEEEHHHHHEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEE
FDGPLSGLTLGTGGRYTGSSYGDPANSFKVGSYTVVDALVRYDLARVGMAGSNVALHVNN
ECCCCCCEEECCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
LFDREYVASCFNTYGCFWGAERQVVATATFRF
HHHHHHHHHHHHHHHHEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]