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The map label for this gene is ccdA [C]

Identifier: 218687925

GI number: 218687925

Start: 52023

End: 52256

Strand: Direct

Name: ccdA [C]

Synonym: ECED1_0048

Alternate gene names: 218687925

Gene position: 52023-52256 (Clockwise)

Preceding gene: 218687924

Following gene: 218687926

Centisome position: 1.0

GC content: 48.72

Gene sequence:

>234_bases
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG

Upstream 100 bases:

>100_bases
CTGGAGCGGCGGTAATTTTGTATATTAGAATTCCGGCATCACTGATACGTGCAGATATCCGTGTATACTAGACGTATAAA
TTGTACAGGAGCACGAGATC

Downstream 100 bases:

>100_bases
CGATGCAATTTACGGTATACCACAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTGTT
GGTGAGATTAATCGCCGTAT

Product: putative antitoxin of gyrase inhibiting toxin-antitoxin system

Products: protein histidine; sugar phosphate [C]

Alternate protein names: Antitoxin Of Gyrase Inhibiting xin-Antitoxin System; CcdA Protein; Protein CcdA; Antitoxin Of Gyrase; Antitoxin Protein LetA; Gyrase Inhibitor Antitoxin

Number of amino acids: Translated: 77; Mature: 76

Protein sequence:

>77_residues
MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKHAATRWREENAEAIAALNQLADETGCFSDEYRSF

Sequences:

>Translated_77_residues
MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKHAATRWREENAEAIAALNQLADETGCFSDEYRSF
>Mature_76_residues
TAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKHAATRWREENAEAIAALNQLADETGCFSDEYRSF

Specific function: Binds To And Blocks The Activity Of Ccdb. Removes The Bound Letd Protein From The Letd-Gyra Complex By Forming A Leta- Letd Complex. [C]

COG id: COG5302

COG function: function code R; Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 8531; Mature: 8399

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKHAATRWREENAEAIAAL
CCCCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHH
NQLADETGCFSDEYRSF
HHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKHAATRWREENAEAIAAL
CCCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHH
NQLADETGCFSDEYRSF
HHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Protein N-phosphohistidine; sugar [C]

Specific reaction: Protein N-phosphohistidine + sugar = protein histidine + sugar phosphate [C]

General reaction: Removes the bound letD protein from the letD-gyrA complex by forming a letA-letD complex [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA