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The map label for this gene is nhaR [H]

Identifier: 218687896

GI number: 218687896

Start: 21053

End: 21958

Strand: Direct

Name: nhaR [H]

Synonym: ECED1_0019

Alternate gene names: 218687896

Gene position: 21053-21958 (Clockwise)

Preceding gene: 218687895

Following gene: 218687898

Centisome position: 0.4

GC content: 47.35

Gene sequence:

>906_bases
ATGAGCATGTCTCATATCAATTACAACCACTTGTATTACTTCTGGCATGTCTACAAAGAAGGTTCTGTGGTTGGCGCAGC
GGAGGCGCTTTATTTAACACCACAAACCATTACCGGGCAGATCCGGGCGCTGGAAGAGCGCCTGCAAGGGAAACTATTTA
AGCGTAAAGGACGTGGTCTGGAACCCAGCGAACTGGGGGAACTGGTCTATCGCTATGCCGATAAAATGTTCACCTTAAGC
CAGGAAATGCTGGATATCGTCAACTATCGCAAAGAGTCCAACTTATTGTTTGATGTTGGTGTGGCAGATGCACTTTCCAA
ACGTCTGGTCAGCAGTGTTCTGGATGCCGCAGTTGTGGAAGACGAGCAGATCCATCTACGCTGTTTCGAATCGACGCACG
AGATGCTTTTAGAGCAGTTGAGTCAGCATAAACTGGATATGATCATCTCTGACTGTCCGATCGATTCCACTCAGCAGGAA
GGGCTGTTTTCCATGAAAATTGGCGAATGTGGTGTCAGTTTCTGGTGCACTAACCCACTACCAGAAAAGCCGTTTCCTGC
CTGTCTTGAAGAGCGTCGTTTACTTATTCCGGGGCGTCGCTCAATGTTGGGGCGTAAACTATTAAACTGGTTTAACTCCC
AGGGCTTGAACGTCGAAATTTTGGGTGAGTTTGATGATGCTGCGTTGATGAAAGCCTTTGGGGCGACGCATAACGCTATT
TTCGTTGCACCTTCGCTTTACGCTAATGATTTCTATAACGATGACTCGGTTGTGGAGATAGGCCGTGTTGAGAACGTGAT
GGAAGAGTACCACGCGATTTTTGCCGAAAGGATGATTCAGCACCCTGCAGTACAGCGTATCTGCAATACAGACTATTCTG
CGCTGTTTACTCCAGCTTCAAAATAA

Upstream 100 bases:

>100_bases
GATATAGCTGGTTACGCGTTCGTTTACGTCCATCAGTTTGACAGGACGATGTACTGGGGAGCCATAAACGGCTCCCTTTT
CATTGTTATCAGGGAGAGAA

Downstream 100 bases:

>100_bases
ACATTTGTACTTTGCAGGCCGAATTTTGGCCTGCAGATGGATATAAAAAAACCCGCCAGAGCGGGTTTTTTTACAAAGCT
GACAACAACAGGCAATTAAG

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSMSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEERLQGKLFKRKGRGLEPSELGELVYRYADKMFTLS
QEMLDIVNYRKESNLLFDVGVADALSKRLVSSVLDAAVVEDEQIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQE
GLFSMKIGECGVSFWCTNPLPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEILGEFDDAALMKAFGATHNAI
FVAPSLYANDFYNDDSVVEIGRVENVMEEYHAIFAERMIQHPAVQRICNTDYSALFTPASK

Sequences:

>Translated_301_residues
MSMSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEERLQGKLFKRKGRGLEPSELGELVYRYADKMFTLS
QEMLDIVNYRKESNLLFDVGVADALSKRLVSSVLDAAVVEDEQIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQE
GLFSMKIGECGVSFWCTNPLPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEILGEFDDAALMKAFGATHNAI
FVAPSLYANDFYNDDSVVEIGRVENVMEEYHAIFAERMIQHPAVQRICNTDYSALFTPASK
>Mature_300_residues
SMSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEERLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQ
EMLDIVNYRKESNLLFDVGVADALSKRLVSSVLDAAVVEDEQIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEG
LFSMKIGECGVSFWCTNPLPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEILGEFDDAALMKAFGATHNAIF
VAPSLYANDFYNDDSVVEIGRVENVMEEYHAIFAERMIQHPAVQRICNTDYSALFTPASK

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=301, Percent_Identity=95.0166112956811, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI1788297, Length=251, Percent_Identity=23.1075697211155, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34292; Mature: 34160

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEERLQGKLFKRKGRGL
CCCCCCCCCEEEEEEEEEECCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCC
EPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADALSKRLVSSVLDAAVVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCC
DEQIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGLFSMKIGECGVSFWCTNPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCEEEEEECCCCCEEEECCCC
PEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEILGEFDDAALMKAFGATHNAI
CCCCCHHHHHCCEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCEE
FVAPSLYANDFYNDDSVVEIGRVENVMEEYHAIFAERMIQHPAVQRICNTDYSALFTPAS
EEECHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCEEECCCC
K
C
>Mature Secondary Structure 
SMSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEERLQGKLFKRKGRGL
CCCCCCCCEEEEEEEEEECCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCC
EPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADALSKRLVSSVLDAAVVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCC
DEQIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGLFSMKIGECGVSFWCTNPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCEEEEEECCCCCEEEECCCC
PEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEILGEFDDAALMKAFGATHNAI
CCCCCHHHHHCCEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCEE
FVAPSLYANDFYNDDSVVEIGRVENVMEEYHAIFAERMIQHPAVQRICNTDYSALFTPAS
EEECHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCEEECCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]