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The map label for this gene is glpG [H]

Identifier: 218550681

GI number: 218550681

Start: 3455810

End: 3456640

Strand: Reverse

Name: glpG [H]

Synonym: EFER_3392

Alternate gene names: 218550681

Gene position: 3456640-3455810 (Counterclockwise)

Preceding gene: 218550682

Following gene: 218550680

Centisome position: 75.33

GC content: 53.55

Gene sequence:

>831_bases
ATGTTGATGATTACCTCTTTTGCTAACCCCCGCGTGGCGCAGGCGTTTGTTGATTACATGGCGACGCAGGGTGTTATCCT
CACGATTCAACAACATAACCAAAGCGATGTCTGGCTGGCGGATGAGTCCCTGGCCGAACGCGTGCGGTCGGAGCTGGCGC
GTTTTCTCGAAAACCCGGCAGATCCTCGTTATCTGGCGGCCAGCTGGCAGGCGGGCCATACCGGCAGCGGCCTGCATTAT
CGCCGTTATCCCTTCTTTGCTGCCTTGCGTGAACGCGCAGGTCCGGTGACCTGGGTGATGATGATCGCCTGCGTGGTGGT
GTTTATCGCCATGCAAATTCTCGGTGATCAGGAAGTGATGTTATGGCTGGCCTGGCCATTCGATCCGACACTGAAATTTG
AGTTCTGGCGTTACTTCACTCATGCATTAATGCACTTCTCGCTGATGCATATCCTTTTTAACCTGCTCTGGTGGTGGTAT
CTCGGCGGCGCGGTGGAAAAACGTCTCGGTAGCGGTAAGCTAATTGTTATTACTCTGATTAGCGCCCTGTTAAGCGGCTA
TGTGCAGCAAAAATTCAGCGGGCCGTGGTTTGGCGGGCTTTCTGGCGTGGTGTATGCACTGATGGGGTACGTCTGGCTAC
GCGGCGAACGCGATCCGCAAAGTGGCATTTACCTGCAACGTGGGTTAATCATCTTTGCACTGATCTGGATTGTCGCCGGA
TGGTTTGATTTGTTTGGGATGTCAATGGCGAACGGAGCACACATCGCCGGGTTAGCCGTGGGTTTAGCGATGGCTTTTGT
TGATTCGCTCAATGCGCGAAAACGAAAATAA

Upstream 100 bases:

>100_bases
GCGGATTTGAAGCCTGGCAGCGTCAGTTTCCAGCAGAGGTGGCGTACGGCGCGTAACGCTTTATACTGTCCCCTTTTGTG
TGGAATAAGCGACAGCAACG

Downstream 100 bases:

>100_bases
TTCCAGGGATTTATAAATGAAACAAACACAACGTCACAACGGTATTATTGAACTGGTTAAACAGCAGGGTTATGTCAGCA
CCGAAGAACTGGTGGAACAC

Product: intramembrane serine protease GlpG

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESLAERVRSELARFLENPADPRYLAASWQAGHTGSGLHY
RRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWY
LGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAG
WFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK

Sequences:

>Translated_276_residues
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESLAERVRSELARFLENPADPRYLAASWQAGHTGSGLHY
RRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWY
LGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAG
WFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
>Mature_276_residues
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESLAERVRSELARFLENPADPRYLAASWQAGHTGSGLHY
RRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWY
LGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAG
WFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=276, Percent_Identity=99.2753623188406, Blast_Score=557, Evalue=1e-160,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 31308; Mature: 31308

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESLAERVRSELARFLENPA
CEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEECHHHHHHHHHHHHHHHCCCC
DPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVM
CCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEE
LWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLI
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
WFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESLAERVRSELARFLENPA
CEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEECHHHHHHHHHHHHHHHCCCC
DPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVM
CCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEE
LWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLI
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
WFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA