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The map label for this gene is argE [H]

Identifier: 218550128

GI number: 218550128

Start: 2882065

End: 2883402

Strand: Direct

Name: argE [H]

Synonym: EFER_2816

Alternate gene names: 218550128

Gene position: 2882065-2883402 (Clockwise)

Preceding gene: 218550127

Following gene: 218550129

Centisome position: 62.81

GC content: 50.52

Gene sequence:

>1338_bases
ATGATTATATCTGGCCAGTTGTTGATCTGCGCATCGACTGGGCTGATGCTGATCCTGTGGCCAGCTTGCAAGCGCTATGG
CAGGCTTATGAACCACAAATGGAGGCGTACATTACCAGAGCACTGGACCCACGTGATGCTCCTGGCTATGGCGTACCGGG
CGATGAATAACTCAGTACAGGAGTTACTCGCGCAGTTGCTGGCTTTTGACACCACCAGCCGGGAATCAAACCTGGCAATG
ATAATGATGATTCGAGATTTCCTCGATGCTCGTGGTGTGACCTCGCAACTCTTTTATGATGATACGGGGTGTAAAGCAAA
TCTGTATGCGCGGATTGGACCGGCAGGAGGCGGAGGCGTCATGCTTTCAGGCCACACCGACGTAGTGCCAATAGATGGAC
AGTCATGGACAGTACCGCCCTTTGCCTTAACGGAACGTGATGGGCGTTTTTACGGACGCGGTAGTGCAGATATGAAAGGG
TTTATTGCCTGTGTACTGGCATCACTGGAAACCTTTCTCGTTGCGCCATTGCGTATGCCACTTCACCTGGCATTTTCGTA
TGACGAAGAAGTGGGTTGCCTGGGAGTGCGCAGCCTCGTGGAGCATATCGGAGCATCCGCAGAAAAACCTGCACTATGCA
TTATCGGTGAGCCAACTGAAATGCAGCCGGTTTTTGGACATAAAGGTAAGTTGGCAATGCGCTGCCGTGTGAACGGTCAC
GCTTGCCACTCTGCCCATGCACCAGAGGGTGTTAACGCAATCAGTTATGCTGCCCAACTGATCAGCCATCTTGATGAACT
GGGCAGTGTCTTTTCTCGCAGGCAAGATCCTCGTTTTACTCCTTGCGGTGCAACAATACAGGTTGGCGTTATTGCTGGCG
GTACTGCCCTGAATATCGTGCCGCAAAGTTGTTGGTTTGATTTTGAGATTCGCTATCTGCCCGGAACGCGTCCGCAAGAT
GTCACCGAAGCCCTGGCGGCCTGGGCCGAAAGCCAGTTACTTCCGTCAATGCGTAAGGTTGCCAAAAGTTCCGAGATTCG
TTTTCAGCAACTTAGCCATTACCCTGGTTTGCTGAGCGATCCGCAAAGCAGTTTTGCCAGAGCACTGGCGCAATGGTGTG
ACAGTACATGTTTCTCAACCGTAGCCTTTGGCACAGAAGGAGGATTGTTTAGTGAAGCGGGTGTGCCAACGCTCATCTGT
GGGCCTGGAAGCATGGCACAAGGGCATAAAGCAGATGAATATGTCAGTATTGCGCAAATTGAGCGCTGCATGACAATGCT
TAAAAATTTATGCGACTGGATGTGTCTGGATAATAAAAATTATTTTGATACAAATTAA

Upstream 100 bases:

>100_bases
ACTGGTGAACTGACCAGCCGTTTACTTGCGGCGCTCCGGGCAGGAATTGATCAGGGAGGCGAAGCTGGCCCGGAACATTC
TGCGGCCGTAAAAGTCGTGG

Downstream 100 bases:

>100_bases
ATGATACGTGCGAACATTATTTTCCGTTGGAAATAGCAATTAAAGCTTCCCATAATAGTAAAAATGGACCACCTTACTTA
CCTAAATATAATACCTTAAT

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MIISGQLLICASTGLMLILWPACKRYGRLMNHKWRRTLPEHWTHVMLLAMAYRAMNNSVQELLAQLLAFDTTSRESNLAM
IMMIRDFLDARGVTSQLFYDDTGCKANLYARIGPAGGGGVMLSGHTDVVPIDGQSWTVPPFALTERDGRFYGRGSADMKG
FIACVLASLETFLVAPLRMPLHLAFSYDEEVGCLGVRSLVEHIGASAEKPALCIIGEPTEMQPVFGHKGKLAMRCRVNGH
ACHSAHAPEGVNAISYAAQLISHLDELGSVFSRRQDPRFTPCGATIQVGVIAGGTALNIVPQSCWFDFEIRYLPGTRPQD
VTEALAAWAESQLLPSMRKVAKSSEIRFQQLSHYPGLLSDPQSSFARALAQWCDSTCFSTVAFGTEGGLFSEAGVPTLIC
GPGSMAQGHKADEYVSIAQIERCMTMLKNLCDWMCLDNKNYFDTN

Sequences:

>Translated_445_residues
MIISGQLLICASTGLMLILWPACKRYGRLMNHKWRRTLPEHWTHVMLLAMAYRAMNNSVQELLAQLLAFDTTSRESNLAM
IMMIRDFLDARGVTSQLFYDDTGCKANLYARIGPAGGGGVMLSGHTDVVPIDGQSWTVPPFALTERDGRFYGRGSADMKG
FIACVLASLETFLVAPLRMPLHLAFSYDEEVGCLGVRSLVEHIGASAEKPALCIIGEPTEMQPVFGHKGKLAMRCRVNGH
ACHSAHAPEGVNAISYAAQLISHLDELGSVFSRRQDPRFTPCGATIQVGVIAGGTALNIVPQSCWFDFEIRYLPGTRPQD
VTEALAAWAESQLLPSMRKVAKSSEIRFQQLSHYPGLLSDPQSSFARALAQWCDSTCFSTVAFGTEGGLFSEAGVPTLIC
GPGSMAQGHKADEYVSIAQIERCMTMLKNLCDWMCLDNKNYFDTN
>Mature_445_residues
MIISGQLLICASTGLMLILWPACKRYGRLMNHKWRRTLPEHWTHVMLLAMAYRAMNNSVQELLAQLLAFDTTSRESNLAM
IMMIRDFLDARGVTSQLFYDDTGCKANLYARIGPAGGGGVMLSGHTDVVPIDGQSWTVPPFALTERDGRFYGRGSADMKG
FIACVLASLETFLVAPLRMPLHLAFSYDEEVGCLGVRSLVEHIGASAEKPALCIIGEPTEMQPVFGHKGKLAMRCRVNGH
ACHSAHAPEGVNAISYAAQLISHLDELGSVFSRRQDPRFTPCGATIQVGVIAGGTALNIVPQSCWFDFEIRYLPGTRPQD
VTEALAAWAESQLLPSMRKVAKSSEIRFQQLSHYPGLLSDPQSSFARALAQWCDSTCFSTVAFGTEGGLFSEAGVPTLIC
GPGSMAQGHKADEYVSIAQIERCMTMLKNLCDWMCLDNKNYFDTN

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=367, Percent_Identity=33.2425068119891, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1788816, Length=371, Percent_Identity=25.8760107816712, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17551016, Length=350, Percent_Identity=25.4285714285714, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 48775; Mature: 48775

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISGQLLICASTGLMLILWPACKRYGRLMNHKWRRTLPEHWTHVMLLAMAYRAMNNSVQ
CEECCCEEEEECCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLAQLLAFDTTSRESNLAMIMMIRDFLDARGVTSQLFYDDTGCKANLYARIGPAGGGGV
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHEEECCCCCCEEEEEEECCCCCCCE
MLSGHTDVVPIDGQSWTVPPFALTERDGRFYGRGSADMKGFIACVLASLETFLVAPLRMP
EEECCCCEEEECCCCCCCCCCEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
LHLAFSYDEEVGCLGVRSLVEHIGASAEKPALCIIGEPTEMQPVFGHKGKLAMRCRVNGH
EEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEECCC
ACHSAHAPEGVNAISYAAQLISHLDELGSVFSRRQDPRFTPCGATIQVGVIAGGTALNIV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCEEEEE
PQSCWFDFEIRYLPGTRPQDVTEALAAWAESQLLPSMRKVAKSSEIRFQQLSHYPGLLSD
ECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PQSSFARALAQWCDSTCFSTVAFGTEGGLFSEAGVPTLICGPGSMAQGHKADEYVSIAQI
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHH
ERCMTMLKNLCDWMCLDNKNYFDTN
HHHHHHHHHHHHHEEECCCCCCCCC
>Mature Secondary Structure
MIISGQLLICASTGLMLILWPACKRYGRLMNHKWRRTLPEHWTHVMLLAMAYRAMNNSVQ
CEECCCEEEEECCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLAQLLAFDTTSRESNLAMIMMIRDFLDARGVTSQLFYDDTGCKANLYARIGPAGGGGV
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHEEECCCCCCEEEEEEECCCCCCCE
MLSGHTDVVPIDGQSWTVPPFALTERDGRFYGRGSADMKGFIACVLASLETFLVAPLRMP
EEECCCCEEEECCCCCCCCCCEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
LHLAFSYDEEVGCLGVRSLVEHIGASAEKPALCIIGEPTEMQPVFGHKGKLAMRCRVNGH
EEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEECCC
ACHSAHAPEGVNAISYAAQLISHLDELGSVFSRRQDPRFTPCGATIQVGVIAGGTALNIV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCEEEEE
PQSCWFDFEIRYLPGTRPQDVTEALAAWAESQLLPSMRKVAKSSEIRFQQLSHYPGLLSD
ECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PQSSFARALAQWCDSTCFSTVAFGTEGGLFSEAGVPTLICGPGSMAQGHKADEYVSIAQI
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHH
ERCMTMLKNLCDWMCLDNKNYFDTN
HHHHHHHHHHHHHEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9829957 [H]