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The map label for this gene is yajO [H]

Identifier: 218549921

GI number: 218549921

Start: 2677252

End: 2678226

Strand: Direct

Name: yajO [H]

Synonym: EFER_2606

Alternate gene names: 218549921

Gene position: 2677252-2678226 (Clockwise)

Preceding gene: 218549920

Following gene: 218549928

Centisome position: 58.34

GC content: 53.54

Gene sequence:

>975_bases
ATGCAATACAACCCCTTAGGAAAAACCGACCTTCGCATTTCCCGACTTTGCCTCGGCTGTATGACCTTTGGCGAGCCGGA
TCGCGGTAATCACGCATGGACACTGCCAGAAGAGAGCAGCCGTCCCATCATTAAACGCGCGCTGGAAGGCGGCATAAATT
TCTTTGATACCGCCAATAGTTATTCTGACGGCAGCAGCGAAGAGATCGTCGGTCGTGCACTGCGGGACTTTGCCCGTCGT
GAAGACGTGGTCGTTGCAACTAAAGTGTTCCATCGCGTTGGTGATTTGCCGGAAGGATTATCCCGTGCGCAAATTTTGCG
CTCAATTGACGACAGCCTACGACGTCTCGGCATGGATTATGTCGATATCCTGCAAATTCATCGCTGGGATTACAACACGC
CGATCGAAGAGACGCTGGAAGCCCTGAACGACGTGGTAAAAGCAGGGAAAGCGCGTTATATCGGCGCGTCATCCATGCAC
GCCTCGCAGTTTGCTCAGGCGCTGGAACTGCAAAAACAGCACGGCTGGGCGCAGTTTGTCAGTATGCAGGATCACTACAA
TCTGATTTATCGCGAAGAAGAACGAGAGATGCTGCCGCTGTGTTATCAGGAAGGCGTGGCGGTGATTCCGTGGAGTCCGC
TGGCGCGGGGACGTCTGACGCGTCCCTGGGGAGAAACCACCGCGCGGCTGGTGTCGGATGAAGTGGGGAAAAATCTCTAC
CAAGAAAGCGATGAAAATGACGCGCAGATCGCAGAACGGTTAACAGGCGTCAGTGAAGAACTGGGGGCAACGCGAGCACA
AGTCGCGCTGGCATGGTTGTTGAGCAAACCTGGCATTGCAGCACCAATTATCGGTACATCGCGGGAAGAACAACTTGATG
AATTGCTGAACGCGGTGGATATCACCTTGAAGCCGGAACAGATTGCTGAACTGGAAACGCCGTATAAACCGCATCCGGTC
GTAGGATTTAAATAG

Upstream 100 bases:

>100_bases
GTGAAGCCCCAGGAGCTTACATAAGTAAGTGACTGGGGTGAACGAATGCAGCCGCAGCACATGCAACTTGAAGTATGACG
AGTATGGCAGGAGTGGCAGC

Downstream 100 bases:

>100_bases
GAATCCAGGCCTGATGAGACGTGACAAGCGTCACATCAGGCGTAGGTGCACAGCTACGACAGAATACCCAGCGGCCAGTG
ATGACCAATAAAGTACAGGA

Product: aldoketo-oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MQYNPLGKTDLRISRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
QESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPV
VGFK

Sequences:

>Translated_324_residues
MQYNPLGKTDLRISRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
QESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPV
VGFK
>Mature_324_residues
MQYNPLGKTDLRISRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
QESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPV
VGFK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=313, Percent_Identity=32.9073482428115, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI27436962, Length=316, Percent_Identity=32.9113924050633, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI27436971, Length=333, Percent_Identity=33.033033033033, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI27436969, Length=315, Percent_Identity=32.0634920634921, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI27436966, Length=313, Percent_Identity=32.5878594249201, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI4504825, Length=313, Percent_Identity=31.9488817891374, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI223718702, Length=280, Percent_Identity=27.8571428571429, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI41152114, Length=283, Percent_Identity=27.5618374558304, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI41327764, Length=273, Percent_Identity=28.2051282051282, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI223718708, Length=139, Percent_Identity=33.8129496402878, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=99.3827160493827, Blast_Score=667, Evalue=0.0,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=35.4545454545455, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1788070, Length=324, Percent_Identity=33.9506172839506, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=27.8735632183908, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788081, Length=301, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787674, Length=328, Percent_Identity=27.7439024390244, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI212645785, Length=313, Percent_Identity=27.7955271565495, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17566692, Length=304, Percent_Identity=23.0263157894737, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=39.2215568862275, Blast_Score=244, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6323998, Length=330, Percent_Identity=31.2121212121212, Blast_Score=142, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6319958, Length=295, Percent_Identity=30.5084745762712, Blast_Score=135, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6319951, Length=315, Percent_Identity=28.2539682539683, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6322615, Length=246, Percent_Identity=31.3008130081301, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6321052, Length=155, Percent_Identity=31.6129032258064, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=27.536231884058, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45549126, Length=345, Percent_Identity=27.536231884058, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24646155, Length=318, Percent_Identity=30.8176100628931, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646159, Length=311, Percent_Identity=29.903536977492, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36435; Mature: 36435

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYNPLGKTDLRISRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANS
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
YSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDY
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
VDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQFAQALELQKQHGWAQFV
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHH
SMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
HHHHHHHHEEECCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVD
HCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
ITLKPEQIAELETPYKPHPVVGFK
CCCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQYNPLGKTDLRISRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANS
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
YSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDY
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
VDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQFAQALELQKQHGWAQFV
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHH
SMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
HHHHHHHHEEECCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVD
HCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
ITLKPEQIAELETPYKPHPVVGFK
CCCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]