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The map label for this gene is aroE [H]

Identifier: 218549907

GI number: 218549907

Start: 2661723

End: 2662586

Strand: Direct

Name: aroE [H]

Synonym: EFER_2592

Alternate gene names: 218549907

Gene position: 2661723-2662586 (Clockwise)

Preceding gene: 218549904

Following gene: 218549908

Centisome position: 58.01

GC content: 46.99

Gene sequence:

>864_bases
TTGAAATACTTAAGCAACATTAAGTTAACAAGAGAGCAAATTATGATTACTGGATTCACTCAGGTTGTGGCTGTTATCGG
GCACCCTATCAACCAGGTTAAATCGCCAGAAAACTTTAACCGTTACTTTGCTCAACAGCAGATGGACAGCGTTATGATCC
CGATTGATATCGAACCAGATGCGGTGGCGGGTTATCTGAATGCGCTACGCGGTTGGAAAAATATGAGCGGCGTACTGGTT
ACTGTTCCACACAAACAACGGGTTGCCGCGTTACTTGATGAATTATCCCCACGTGCCATGCATCTGAATGCCGTCAATGT
AGTGAGAAAATTGCCTGATGGTCGTTTGAAGGGCGACATGCTGGATGGTGTGGGATTTTTGCTGGCTGCAAAAGAACATA
ATTTTCAGTCATCAGGTAAGAAAGCCTTGCTTTCTGGCTGTGGCGGTGTCGGAAGTGCCATTGCATGGGGGCTTTGTGAA
GCAGGTGCGACTCATCTTGCCATTTATGATCAAAATCCGGCAATGCAACAGAGTCTCTTTAATCGTCTTGCCACACATTT
CCCGCATGTTCATCTCTCTTCATTACCAGAAACTTTACAGGATATTGATATCCTTATTAATGGTTCTCCTGCCGGAATGG
TGGGCTTTGATCCTTTACCCATCCCGCCAGCGTTACTGGAAACATTAACTTCGGCTACGCATGTTGCTGACGTAGTCACT
GCCCCTGTGATGACACCACTGCTAACTTTTGCTCAGCAGCGTGGTTGTGTTATCCAGACCGGGCCAGAAATGGCACTGGC
ACAAATGAAACTGATGGGCGAATTTATCGGAGCGATGCCTCAACAGGAAGAGGCCGCAGCATGA

Upstream 100 bases:

>100_bases
CATTTTCGCAACAAAAAAGTAATTGTAGCGCGATTATCGCAATGGTGGTGCGATTAACAGGCAAGCTGTCCGAATTCTGC
ATTGCTGCTCTCAGATTCCG

Downstream 100 bases:

>100_bases
AAAGCTGGGATGTCGTTGTCATTGGTAGCGGCGCAGCAGGCTTTGCCGCTGCCGTTTCCGCCTGCTGTAAAGGGCTTTCA
GTACTGATGCTGGAAAAAGC

Product: shikimate dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKYLSNIKLTREQIMITGFTQVVAVIGHPINQVKSPENFNRYFAQQQMDSVMIPIDIEPDAVAGYLNALRGWKNMSGVLV
TVPHKQRVAALLDELSPRAMHLNAVNVVRKLPDGRLKGDMLDGVGFLLAAKEHNFQSSGKKALLSGCGGVGSAIAWGLCE
AGATHLAIYDQNPAMQQSLFNRLATHFPHVHLSSLPETLQDIDILINGSPAGMVGFDPLPIPPALLETLTSATHVADVVT
APVMTPLLTFAQQRGCVIQTGPEMALAQMKLMGEFIGAMPQQEEAAA

Sequences:

>Translated_287_residues
MKYLSNIKLTREQIMITGFTQVVAVIGHPINQVKSPENFNRYFAQQQMDSVMIPIDIEPDAVAGYLNALRGWKNMSGVLV
TVPHKQRVAALLDELSPRAMHLNAVNVVRKLPDGRLKGDMLDGVGFLLAAKEHNFQSSGKKALLSGCGGVGSAIAWGLCE
AGATHLAIYDQNPAMQQSLFNRLATHFPHVHLSSLPETLQDIDILINGSPAGMVGFDPLPIPPALLETLTSATHVADVVT
APVMTPLLTFAQQRGCVIQTGPEMALAQMKLMGEFIGAMPQQEEAAA
>Mature_287_residues
MKYLSNIKLTREQIMITGFTQVVAVIGHPINQVKSPENFNRYFAQQQMDSVMIPIDIEPDAVAGYLNALRGWKNMSGVLV
TVPHKQRVAALLDELSPRAMHLNAVNVVRKLPDGRLKGDMLDGVGFLLAAKEHNFQSSGKKALLSGCGGVGSAIAWGLCE
AGATHLAIYDQNPAMQQSLFNRLATHFPHVHLSSLPETLQDIDILINGSPAGMVGFDPLPIPPALLETLTSATHVADVVT
APVMTPLLTFAQQRGCVIQTGPEMALAQMKLMGEFIGAMPQQEEAAA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=271, Percent_Identity=27.6752767527675, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789675, Length=241, Percent_Identity=31.1203319502075, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30925; Mature: 30925

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLSNIKLTREQIMITGFTQVVAVIGHPINQVKSPENFNRYFAQQQMDSVMIPIDIEPD
CCCHHCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCEEEEEECCCH
AVAGYLNALRGWKNMSGVLVTVPHKQRVAALLDELSPRAMHLNAVNVVRKLPDGRLKGDM
HHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCHH
LDGVGFLLAAKEHNFQSSGKKALLSGCGGVGSAIAWGLCEAGATHLAIYDQNPAMQQSLF
HHCHHHEEEECCCCCHHCCHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
NRLATHFPHVHLSSLPETLQDIDILINGSPAGMVGFDPLPIPPALLETLTSATHVADVVT
HHHHHHCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
APVMTPLLTFAQQRGCVIQTGPEMALAQMKLMGEFIGAMPQQEEAAA
HHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHCCC
>Mature Secondary Structure
MKYLSNIKLTREQIMITGFTQVVAVIGHPINQVKSPENFNRYFAQQQMDSVMIPIDIEPD
CCCHHCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCEEEEEECCCH
AVAGYLNALRGWKNMSGVLVTVPHKQRVAALLDELSPRAMHLNAVNVVRKLPDGRLKGDM
HHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCHH
LDGVGFLLAAKEHNFQSSGKKALLSGCGGVGSAIAWGLCEAGATHLAIYDQNPAMQQSLF
HHCHHHEEEECCCCCHHCCHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
NRLATHFPHVHLSSLPETLQDIDILINGSPAGMVGFDPLPIPPALLETLTSATHVADVVT
HHHHHHCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
APVMTPLLTFAQQRGCVIQTGPEMALAQMKLMGEFIGAMPQQEEAAA
HHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA