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The map label for this gene is entD [H]

Identifier: 218549830

GI number: 218549830

Start: 2579009

End: 2579818

Strand: Direct

Name: entD [H]

Synonym: EFER_2513

Alternate gene names: 218549830

Gene position: 2579009-2579818 (Clockwise)

Preceding gene: 218549829

Following gene: 218549833

Centisome position: 56.2

GC content: 49.75

Gene sequence:

>810_bases
GTGCGCGTCGTTCATGCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAATCTTGCCAATTCAATATATTGCAGGA
TAGTGTAGGCCTGATAAGCGTAGCGCATCAGGCAGTTTTGCGTTTGTCATCAGTCTCTAATATGGTCGACATGAAAACTA
CGCATACCTCCCTCCCCTTTGCCGGACATACGCTGCATTTTGTTGAGTTCGATCCAGTAAGTTTTCGCGAGCAGGATTTA
CTCTGGCTGCCACACTACGCACAACTGCAACACGCTGGACGTAAACGTAAAACAGAGCATTTAGCCGGACGGATCGCTGC
TGTTTACGCCTTGCGGGAATATGGCTATAAATGTGTGCCCGCAATCGGCGAGCTACGCCAACCTGTGTGGCCTGCGGAGG
TATACGGCAGTATTAGCCACTGCGGGACTACGGCATTGGCAGTGGTATCCCGTCAACAGATTGGCATTGATATCGAAGAG
ATTTTCTCTGTACAAACCGCAAGAGAATTGACAGACAACATTATTACACCAGCAGAACACGAGCGACTCGCAGAATGCGG
TTTAACCTTTTCTCTGGCGCTGACACTGGCATTTTCCGCCAAAGAGAGCGCATTTAAGACAGGCGAGATCCAAACTGATG
CCGGTTTTCAGCACTACCAAATTGGAAATTGTCAGCATCAACAGATGAAGATAAGTGGGCCGAATGGCGACCATATTGTG
CAGTGGTTAGTAAGGGGTAATAACGTTATTACCTTGTGCCGGGCAGATAAACACCCGCACACTGCCGCATGCGGGTTGTC
TGGCGGATAA

Upstream 100 bases:

>100_bases
TATCGCGGGTGCCGGGGCGTATACCTATAACGAGCCGGGACGTACATGGTATATGAGCGTAAACACTCACTTCTGATGCT
AACGTCAGATTGTTGACAAA

Downstream 100 bases:

>100_bases
TTCAAAGCATTTCCCGTGCCTGAGCTGCAATTCCGGCAGCATCAAAGCCATGATGCTGACGCAACCACCCACGATCCGCC
GCTGCGGCATATTCTCCATC

Product: phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex

Products: NA

Alternate protein names: Enterobactin synthase component D; Enterochelin synthase D [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MRVVHAGCGVNALSGLQKSCQFNILQDSVGLISVAHQAVLRLSSVSNMVDMKTTHTSLPFAGHTLHFVEFDPVSFREQDL
LWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVPAIGELRQPVWPAEVYGSISHCGTTALAVVSRQQIGIDIEE
IFSVQTARELTDNIITPAEHERLAECGLTFSLALTLAFSAKESAFKTGEIQTDAGFQHYQIGNCQHQQMKISGPNGDHIV
QWLVRGNNVITLCRADKHPHTAACGLSGG

Sequences:

>Translated_269_residues
MRVVHAGCGVNALSGLQKSCQFNILQDSVGLISVAHQAVLRLSSVSNMVDMKTTHTSLPFAGHTLHFVEFDPVSFREQDL
LWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVPAIGELRQPVWPAEVYGSISHCGTTALAVVSRQQIGIDIEE
IFSVQTARELTDNIITPAEHERLAECGLTFSLALTLAFSAKESAFKTGEIQTDAGFQHYQIGNCQHQQMKISGPNGDHIV
QWLVRGNNVITLCRADKHPHTAACGLSGG
>Mature_269_residues
MRVVHAGCGVNALSGLQKSCQFNILQDSVGLISVAHQAVLRLSSVSNMVDMKTTHTSLPFAGHTLHFVEFDPVSFREQDL
LWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVPAIGELRQPVWPAEVYGSISHCGTTALAVVSRQQIGIDIEE
IFSVQTARELTDNIITPAEHERLAECGLTFSLALTLAFSAKESAFKTGEIQTDAGFQHYQIGNCQHQQMKISGPNGDHIV
QWLVRGNNVITLCRADKHPHTAACGLSGG

Specific function: Catalyzes the transfer of the 4'-phosphopantetheine moiety from coenzyme A to apo-domains of both entB (an ArCP domain) and entF (a PCP domain). Plays an essential role in the assembly of the enterobactin [H]

COG id: COG2977

COG function: function code Q; Phosphopantetheinyl transferase component of siderophore synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. EntD family [H]

Homologues:

Organism=Escherichia coli, GI1786797, Length=209, Percent_Identity=84.2105263157895, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR003542 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: 2.7.8.-

Molecular weight: Translated: 29466; Mature: 29466

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVHAGCGVNALSGLQKSCQFNILQDSVGLISVAHQAVLRLSSVSNMVDMKTTHTSLPF
CEEEECCCCCHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AGHTLHFVEFDPVSFREQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVP
CCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
AIGELRQPVWPAEVYGSISHCGTTALAVVSRQQIGIDIEEIFSVQTARELTDNIITPAEH
CHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHH
ERLAECGLTFSLALTLAFSAKESAFKTGEIQTDAGFQHYQIGNCQHQQMKISGPNGDHIV
HHHHHHCCCEEEHHHHHHHCCHHCCCCCCEECCCCCCEEECCCCCCCEEEECCCCHHHHH
QWLVRGNNVITLCRADKHPHTAACGLSGG
HHEECCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVVHAGCGVNALSGLQKSCQFNILQDSVGLISVAHQAVLRLSSVSNMVDMKTTHTSLPF
CEEEECCCCCHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AGHTLHFVEFDPVSFREQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVP
CCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
AIGELRQPVWPAEVYGSISHCGTTALAVVSRQQIGIDIEEIFSVQTARELTDNIITPAEH
CHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHH
ERLAECGLTFSLALTLAFSAKESAFKTGEIQTDAGFQHYQIGNCQHQQMKISGPNGDHIV
HHHHHHCCCEEEHHHHHHHCCHHCCCCCCEECCCCCCEEECCCCCCCEEEECCCCHHHHH
QWLVRGNNVITLCRADKHPHTAACGLSGG
HHEECCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]