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The map label for this gene is nadD

Identifier: 218549786

GI number: 218549786

Start: 2531622

End: 2532263

Strand: Direct

Name: nadD

Synonym: EFER_2467

Alternate gene names: 218549786

Gene position: 2531622-2532263 (Clockwise)

Preceding gene: 218549785

Following gene: 218549787

Centisome position: 55.17

GC content: 48.44

Gene sequence:

>642_bases
ATGAAATCTTTACAGGCGTTGTTTGGTGGCACCTTCGATCCGGTGCATTATGGTCATCTTATTCCCGTAGAAACGCTGGC
AAATTTGATTGCCCTATCACGGGTGATTATCATGCCCAACAATGTCCCCCCGCATCGCCCACAACCTGAAGCAACTTCTG
TGCAGCGTAAAGAGATGCTCGCTCTGGCGATTTCCGACAAGCCTCTTTTTACCCTGGACGAGCGGGAATTGTTACGCAAT
ACCCCTTCGTACACTGCTGAAACACTCAAAGCGTGGCGCGAAGAACAAGGTGCGGATGCTCCACTGGCGTTCATCATTGG
TCAGGATTCTCTGCTAACACTTCCAACATGGCATGATTACGAGAGCATTCTCGACAACGCTCATTTAATTGTCTGCCGCC
GTCCTGGGTACTCTATGGAAATGGCCTCACCAAAATACCAACAGTGGCTGGAGCGGCATATGACCTATAACCCGGAAAAT
TTGCACTCATCACCGGCAGGCAAAATTTATCTTGCTGAAACTCCATGGCTTAATATCTCTGCATCACTTATTCGTGAGAG
GCTGATGAAAGGAGAATCCTGCGAAGATTTAGTGCCAGAATCAGTGCTGGAGTACATTAATCAGCACGGCCTCTATCGGT
AA

Upstream 100 bases:

>100_bases
CAAACAAGATTATGGTCAGTCAGTATGGGCAGAACTTGAAGGACTTTCTCTGCTGCTTTGTCATAAAGCGCTGGCTGATG
TATTCATTGATGGTTAAAAA

Downstream 100 bases:

>100_bases
ATTTCTCTTTTTTACCAGGCGGAACATTTCCGCCATTGACACCCCCATGCAGCCTGATATTCTCCGCAGCCAGACTTTTT
CCGCTATGCAGAGCGTTGTA

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKSLQALFGGTFDPVHYGHLIPVETLANLIALSRVIIMPNNVPPHRPQPEATSVQRKEMLALAISDKPLFTLDERELLRN
TPSYTAETLKAWREEQGADAPLAFIIGQDSLLTLPTWHDYESILDNAHLIVCRRPGYSMEMASPKYQQWLERHMTYNPEN
LHSSPAGKIYLAETPWLNISASLIRERLMKGESCEDLVPESVLEYINQHGLYR

Sequences:

>Translated_213_residues
MKSLQALFGGTFDPVHYGHLIPVETLANLIALSRVIIMPNNVPPHRPQPEATSVQRKEMLALAISDKPLFTLDERELLRN
TPSYTAETLKAWREEQGADAPLAFIIGQDSLLTLPTWHDYESILDNAHLIVCRRPGYSMEMASPKYQQWLERHMTYNPEN
LHSSPAGKIYLAETPWLNISASLIRERLMKGESCEDLVPESVLEYINQHGLYR
>Mature_213_residues
MKSLQALFGGTFDPVHYGHLIPVETLANLIALSRVIIMPNNVPPHRPQPEATSVQRKEMLALAISDKPLFTLDERELLRN
TPSYTAETLKAWREEQGADAPLAFIIGQDSLLTLPTWHDYESILDNAHLIVCRRPGYSMEMASPKYQQWLERHMTYNPEN
LHSSPAGKIYLAETPWLNISASLIRERLMKGESCEDLVPESVLEYINQHGLYR

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=213, Percent_Identity=81.6901408450704, Blast_Score=372, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_ESCF3 (B7LLH4)

Other databases:

- EMBL:   CU928158
- RefSeq:   YP_002383577.1
- ProteinModelPortal:   B7LLH4
- EnsemblBacteria:   EBESCT00000123314
- GeneID:   7122208
- GenomeReviews:   CU928158_GR
- KEGG:   efe:EFER_2467
- GeneTree:   EBGT00050000009314
- HOGENOM:   HBG739448
- ProtClustDB:   PRK00071
- BioCyc:   EFER585054:EFER_2467-MONOMER
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR019450
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2; PF10362 DUF2432

EC number: =2.7.7.18

Molecular weight: Translated: 24263; Mature: 24263

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLQALFGGTFDPVHYGHLIPVETLANLIALSRVIIMPNNVPPHRPQPEATSVQRKEML
CCCHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHE
ALAISDKPLFTLDERELLRNTPSYTAETLKAWREEQGADAPLAFIIGQDSLLTLPTWHDY
EEEECCCCCEEECHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCCH
ESILDNAHLIVCRRPGYSMEMASPKYQQWLERHMTYNPENLHSSPAGKIYLAETPWLNIS
HHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHCCCCCCCEEEEECCCCCCCH
ASLIRERLMKGESCEDLVPESVLEYINQHGLYR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKSLQALFGGTFDPVHYGHLIPVETLANLIALSRVIIMPNNVPPHRPQPEATSVQRKEML
CCCHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHE
ALAISDKPLFTLDERELLRNTPSYTAETLKAWREEQGADAPLAFIIGQDSLLTLPTWHDY
EEEECCCCCEEECHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCCH
ESILDNAHLIVCRRPGYSMEMASPKYQQWLERHMTYNPENLHSSPAGKIYLAETPWLNIS
HHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHCCCCCCCEEEEECCCCCCCH
ASLIRERLMKGESCEDLVPESVLEYINQHGLYR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA