Click here to switch to the map view.

The map label for this gene is ybeX

Identifier: 218549765

GI number: 218549765

Start: 2508277

End: 2509155

Strand: Direct

Name: ybeX

Synonym: EFER_2444

Alternate gene names: 218549765

Gene position: 2508277-2509155 (Clockwise)

Preceding gene: 218549764

Following gene: 218549766

Centisome position: 54.66

GC content: 51.65

Gene sequence:

>879_bases
ATGAGCGACGACAATTCACACAGTAGTGACACGATAAGCAACAAGAAGGGATTTTTCTCCCTGTTACTCAGCCAACTTTT
CCACGGTGAACCGAAAAACCGTGACGAACTGCTGGCGCTGATCCGTGATTCCGGGCAGAACGACCTTATCGACGAAGATA
CGCGCGATATGCTCGAAGGGGTGATGGACATCGCAGACCAACGCGTTCGCGACATCATGATCCCCCGCTCCCAGATGATT
ACCCTGAAACGCAACCAGACGCTGGACGAATGCCTTGATGTCATCATCGAGTCCGCCCACTCACGTTTCCCGGTGATTAG
CGAAGACAAAGATCACATTGAAGGGATTCTGATGGCGAAAGACTTGCTGCCGTTTATGCGCAGCGATGCCGAAGCCTTCA
GCATGGACAAAGTGTTACGTCAGGCGGTTGTCGTTCCTGAAAGTAAGCGCGTAGACCGGATGCTGAAAGAGTTTCGCTCT
CAGCGTTACCACATGGCGATCGTCATTGACGAATTCGGTGGGGTTTCCGGTCTGGTGACCATTGAAGATATCCTGGAACT
GATTGTTGGTGAGATTGAAGACGAGTATGACGAAGAAGATGATATCGACTTCCGTCAGCTGAGTCGTCATACCTGGACCG
TGCGTGCACTGGCTTCCATCGAAGATTTCAACGAAGCCTTCGGCACCCACTTTAGCGATGAAGAGGTCGACACTATCGGT
GGTCTGGTGATGCAAGCGTTTGGGCATCTTCCGGCACGTGGCGAAACCATCGACATCGACGGTTACCAGTTCAAAGTGGC
GATGGCTGACAGTCGGCGTATTATTCAGGTTCATGTCAAAATCCCGGATGACTCACCCCAGCCAAAGCTGGATGAATAA

Upstream 100 bases:

>100_bases
AGAAAGAATAATTTGCCAGGCATTTGACTGGCAGACGTCCCCGCCGTTGGTGATTAACGACGGCGTTTTGATTAACTAAC
ATGAGAACCCATACGACGCC

Downstream 100 bases:

>100_bases
AACCGAAACTGGATAGATAACTACATGGCTTTTGCCTCATTAATTGAACGCCAGCGCATTCGCCTGCTGCTGGCGTTATT
ATTCGGTGCCTGCGGAACGC

Product: protein involved in divalent ion export

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI
TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS
QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG
GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE

Sequences:

>Translated_292_residues
MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI
TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS
QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG
GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE
>Mature_291_residues
SDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMIT
LKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQ
RYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGG
LVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE

Specific function: Plays a role in the transport of magnesium and cobalt ions

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

Organism=Homo sapiens, GI310128564, Length=206, Percent_Identity=32.0388349514563, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI94681046, Length=182, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI40068053, Length=186, Percent_Identity=30.1075268817204, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI40068055, Length=186, Percent_Identity=30.1075268817204, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786879, Length=292, Percent_Identity=100, Blast_Score=588, Evalue=1e-169,
Organism=Escherichia coli, GI87082033, Length=250, Percent_Identity=28, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788119, Length=225, Percent_Identity=32.4444444444444, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI145693175, Length=250, Percent_Identity=26.4, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790664, Length=262, Percent_Identity=24.0458015267176, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CORC_ECO57 (P0AE80)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C85566
- PIR:   H90715
- RefSeq:   NP_286383.1
- RefSeq:   NP_308723.1
- ProteinModelPortal:   P0AE80
- SMR:   P0AE80
- PRIDE:   P0AE80
- EnsemblBacteria:   EBESCT00000026047
- EnsemblBacteria:   EBESCT00000057149
- GeneID:   917057
- GeneID:   957717
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z0807
- KEGG:   ecs:ECs0696
- GeneTree:   EBGT00050000010862
- HOGENOM:   HBG673071
- OMA:   VTHHFGR
- ProtClustDB:   PRK15094
- BioCyc:   ECOL83334:ECS0696-MONOMER
- GO:   GO:0006810
- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170
- Gene3D:   G3DSA:3.30.465.10
- SMART:   SM00116

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC

EC number: NA

Molecular weight: Translated: 33299; Mature: 33168

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK
HHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT
HHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEE
IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE
HHHHHHHCCCCCCCCEEECCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK
HHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT
HHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEE
IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE
HHHHHHHCCCCCCCCEEECCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796