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The map label for this gene is flgM [H]

Identifier: 218549201

GI number: 218549201

Start: 1908643

End: 1908936

Strand: Direct

Name: flgM [H]

Synonym: EFER_1858

Alternate gene names: 218549201

Gene position: 1908643-1908936 (Clockwise)

Preceding gene: 218549200

Following gene: 218549202

Centisome position: 41.59

GC content: 46.6

Gene sequence:

>294_bases
ATGAGTATTGATCGCACTTCCCCTTTAAATCCGGTTAGCAATGTACAACCGCGAGAAACAACTGATCCAGCAGTAGCCAA
AACACGTGCGGAAAAGTCCACGACCACGAATAGCACCAGCGTAAATCTAAGCAGCGCGCAGAAAGAGTTAATGCAACCCA
GCACCAGCGATATCAATAGCGAACGCGTTGAGGCGTTAAAAGCAGCCATTCGCAATGGTGAATTAAAGATGGATACCGGG
AAGATTGCTGATGCGCTGATCCGCGAAACTCAGAGCTATTTACAGAGTAATTAA

Upstream 100 bases:

>100_bases
AAACCTGTAATGCGTTAAAGATTTCATCATCGATGCCGATAGATAAGCAATAAATACGATAGCTGAACGCCACAGCCTGC
AACCTCAATGAGGAAAGAAT

Downstream 100 bases:

>100_bases
TTGTATGTCGCGCCTGGCCGAAATACTTGATCAAATGACCACCGTTCTCAATGAACTGGAAGTCGTCATGGATAATGAAC
AGCAGCAGCTTTGCATGGGG

Product: anti-sigma28 factor FlgM

Products: NA

Alternate protein names: Anti-sigma-28 factor [H]

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MSIDRTSPLNPVSNVQPRETTDPAVAKTRAEKSTTTNSTSVNLSSAQKELMQPSTSDINSERVEALKAAIRNGELKMDTG
KIADALIRETQSYLQSN

Sequences:

>Translated_97_residues
MSIDRTSPLNPVSNVQPRETTDPAVAKTRAEKSTTTNSTSVNLSSAQKELMQPSTSDINSERVEALKAAIRNGELKMDTG
KIADALIRETQSYLQSN
>Mature_96_residues
SIDRTSPLNPVSNVQPRETTDPAVAKTRAEKSTTTNSTSVNLSSAQKELMQPSTSDINSERVEALKAAIRNGELKMDTGK
IADALIRETQSYLQSN

Specific function: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of

COG id: COG2747

COG function: function code KNU; Negative regulator of flagellin synthesis (anti-sigma28 factor)

Gene ontology:

Cell location: Cytoplasm. Note=After completion of the hook-basal body structure, it is exported out of the cell through the completely assembled hook-basal body structures [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flgM family [H]

Homologues:

Organism=Escherichia coli, GI1787311, Length=97, Percent_Identity=75.2577319587629, Blast_Score=126, Evalue=2e-31,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007412 [H]

Pfam domain/function: PF04316 FlgM [H]

EC number: NA

Molecular weight: Translated: 10537; Mature: 10406

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDRTSPLNPVSNVQPRETTDPAVAKTRAEKSTTTNSTSVNLSSAQKELMQPSTSDINS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCH
ERVEALKAAIRNGELKMDTGKIADALIRETQSYLQSN
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIDRTSPLNPVSNVQPRETTDPAVAKTRAEKSTTTNSTSVNLSSAQKELMQPSTSDINS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCH
ERVEALKAAIRNGELKMDTGKIADALIRETQSYLQSN
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655712; 8288531; 8200538; 11677609 [H]