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The map label for this gene is yeaJ [H]

Identifier: 218549155

GI number: 218549155

Start: 1865534

End: 1867036

Strand: Direct

Name: yeaJ [H]

Synonym: EFER_1808

Alternate gene names: 218549155

Gene position: 1865534-1867036 (Clockwise)

Preceding gene: 218549154

Following gene: 218549156

Centisome position: 40.65

GC content: 44.11

Gene sequence:

>1503_bases
GTGCTAAATATCATGAAATTGCACCATAGAATGCTCCGGCATTTTATCGCCGCAAGTGTCATTATACTGACTTCTTCCTT
CCTTATTTACGAACTCATTGCCAGCGACCGGGCAATGACCGCCTATCTGCACTACATTGTGCAGCGAGCTGATTCGTCTT
TTTTGTATGATAAATATCAGAACCAGAGCATAGCCGCGCACCTGATGCGGGCCTTTGCTACGCCCAGAGAACCCATTAGT
GATGAACAAAAACAGGATATTTGCCGTTCCTGGGAAAGCATGAACGGCATTTACGGTATGAACCTTGTGCGTCATACCTA
CCCAGGTTTGCACGGTACACTGCAATCGACTTCCGCAGATTGTAATGATCTGGCCGAGGATATTTCCTTGCTGCCTGCTT
TTGACCAGGCCGTAAAAGCAAATCGCCATCAGGATGATTATGGTAAAGGCTTAGGTCTCACTGAAGAGAAGTTTCACTAT
TACCTCGATCTCAGTAATCGTTATGTCTATTTTTACGAGCAGATCGACTCCGAAAATTTCATCATGAACAACTGGTCCTT
TTTACATCGGGGCACCATGGGGATCGACCATAAAATACTCGACAATGTCTTTACCGGCAGAACGGTGCTTTCCAGTATTT
ATAAGGATAATCTTACCGGGAAAAATATCATGAGTTTTTTAACCCCGGTTTATCGTGCCGGGCAGTTGAAAGGTATGGTG
CTGGTCGATATTGACAACGAAAATCTTTATAACATTTTCTATACAAGAAACCGCCCACTGGCGTGGCAATATCTCAATGT
CACACTGAGTGATTTGGATTCTGGCCAGGATATTGTCGTTCACAAAAGTGAAAGCAATCTCTTTTCCTACGTTAAATACG
TCCAGGATTTACCTGGCGGTATGCGCATCACTTTATCGCTGGATATCCTCTATTTCTTTGCTTCTTCCTGGAAAGCCTTT
GCTTTCTATTTAGTGGCGACTGCCCTGCTGCTAAATATGGTACGCATGCATTTTCGTCTCTACTTCAATGTTACGCGTGA
AAATATCAGCGATGCGATGACGGGATTGTATAACCGCAAAATTCTGACCTCATCCCTTGAGCAGCGTTTGCAACGATTAG
CTGAAACGGGAAAAGCCGTATTTTTTATCTCGCTGGATTTAGACAACCTGAAAGTGATTAATGACACGTTGGGTCATCAT
GAAGGGGATCTGGCTATTTCTCTGCTGGCAAAGGCAATAAAAAGCTCGGTGCGTAAGAGTGATTATGCAATTCGCCTCGG
TGGTGATGAATTTTGCGTGATCTTGATCGATTCCACCGAAGAGACCGCCTCTGGCCTCGCTGACCGTATTGCGAAAAAAA
TGCATAGCATTGCGCCGGATAAAGATTTCCGCTTTTCTTCTGGCTATTACAGGATGAAACCAGGCGATACGCTTAATGAT
GCTTATAAAGCTTCCGATGCACAACTCTATATCAACAAACATCAACATCACATGTCTTCGTGA

Upstream 100 bases:

>100_bases
ATTTCCCTGTTTCTTGGCCGCGCGCTGAGTATAATTACCCGCCTTTGCGCCGTTCGCTTCGCGTATTTCATCTGATTTTC
TCATTTCCCTGACAGGAGGA

Downstream 100 bases:

>100_bases
TACCCTTGATGGTTGTTTTTGTAGGAAAATCGGGAGTTATCGATGACTGAAGTTGTAAAAGGCATGGCGACTCACCAACG
GTTGATTGCCTTGCTGACAC

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MLNIMKLHHRMLRHFIAASVIILTSSFLIYELIASDRAMTAYLHYIVQRADSSFLYDKYQNQSIAAHLMRAFATPREPIS
DEQKQDICRSWESMNGIYGMNLVRHTYPGLHGTLQSTSADCNDLAEDISLLPAFDQAVKANRHQDDYGKGLGLTEEKFHY
YLDLSNRYVYFYEQIDSENFIMNNWSFLHRGTMGIDHKILDNVFTGRTVLSSIYKDNLTGKNIMSFLTPVYRAGQLKGMV
LVDIDNENLYNIFYTRNRPLAWQYLNVTLSDLDSGQDIVVHKSESNLFSYVKYVQDLPGGMRITLSLDILYFFASSWKAF
AFYLVATALLLNMVRMHFRLYFNVTRENISDAMTGLYNRKILTSSLEQRLQRLAETGKAVFFISLDLDNLKVINDTLGHH
EGDLAISLLAKAIKSSVRKSDYAIRLGGDEFCVILIDSTEETASGLADRIAKKMHSIAPDKDFRFSSGYYRMKPGDTLND
AYKASDAQLYINKHQHHMSS

Sequences:

>Translated_500_residues
MLNIMKLHHRMLRHFIAASVIILTSSFLIYELIASDRAMTAYLHYIVQRADSSFLYDKYQNQSIAAHLMRAFATPREPIS
DEQKQDICRSWESMNGIYGMNLVRHTYPGLHGTLQSTSADCNDLAEDISLLPAFDQAVKANRHQDDYGKGLGLTEEKFHY
YLDLSNRYVYFYEQIDSENFIMNNWSFLHRGTMGIDHKILDNVFTGRTVLSSIYKDNLTGKNIMSFLTPVYRAGQLKGMV
LVDIDNENLYNIFYTRNRPLAWQYLNVTLSDLDSGQDIVVHKSESNLFSYVKYVQDLPGGMRITLSLDILYFFASSWKAF
AFYLVATALLLNMVRMHFRLYFNVTRENISDAMTGLYNRKILTSSLEQRLQRLAETGKAVFFISLDLDNLKVINDTLGHH
EGDLAISLLAKAIKSSVRKSDYAIRLGGDEFCVILIDSTEETASGLADRIAKKMHSIAPDKDFRFSSGYYRMKPGDTLND
AYKASDAQLYINKHQHHMSS
>Mature_500_residues
MLNIMKLHHRMLRHFIAASVIILTSSFLIYELIASDRAMTAYLHYIVQRADSSFLYDKYQNQSIAAHLMRAFATPREPIS
DEQKQDICRSWESMNGIYGMNLVRHTYPGLHGTLQSTSADCNDLAEDISLLPAFDQAVKANRHQDDYGKGLGLTEEKFHY
YLDLSNRYVYFYEQIDSENFIMNNWSFLHRGTMGIDHKILDNVFTGRTVLSSIYKDNLTGKNIMSFLTPVYRAGQLKGMV
LVDIDNENLYNIFYTRNRPLAWQYLNVTLSDLDSGQDIVVHKSESNLFSYVKYVQDLPGGMRITLSLDILYFFASSWKAF
AFYLVATALLLNMVRMHFRLYFNVTRENISDAMTGLYNRKILTSSLEQRLQRLAETGKAVFFISLDLDNLKVINDTLGHH
EGDLAISLLAKAIKSSVRKSDYAIRLGGDEFCVILIDSTEETASGLADRIAKKMHSIAPDKDFRFSSGYYRMKPGDTLND
AYKASDAQLYINKHQHHMSS

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081974, Length=496, Percent_Identity=67.5403225806452, Blast_Score=726, Evalue=0.0,
Organism=Escherichia coli, GI87082007, Length=184, Percent_Identity=32.6086956521739, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI145693134, Length=117, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786584, Length=148, Percent_Identity=31.0810810810811, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081881, Length=146, Percent_Identity=33.5616438356164, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787816, Length=161, Percent_Identity=29.8136645962733, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788381, Length=100, Percent_Identity=40, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787262, Length=110, Percent_Identity=33.6363636363636, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081977, Length=150, Percent_Identity=29.3333333333333, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160 [H]

Pfam domain/function: PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 57302; Mature: 57302

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIMKLHHRMLRHFIAASVIILTSSFLIYELIASDRAMTAYLHYIVQRADSSFLYDKYQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHC
NQSIAAHLMRAFATPREPISDEQKQDICRSWESMNGIYGMNLVRHTYPGLHGTLQSTSAD
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCC
CNDLAEDISLLPAFDQAVKANRHQDDYGKGLGLTEEKFHYYLDLSNRYVYFYEQIDSENF
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHEEEEEEECCCEEEEEEEECCCCE
IMNNWSFLHRGTMGIDHKILDNVFTGRTVLSSIYKDNLTGKNIMSFLTPVYRAGQLKGMV
EECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEE
LVDIDNENLYNIFYTRNRPLAWQYLNVTLSDLDSGQDIVVHKSESNLFSYVKYVQDLPGG
EEEECCCCEEEEEEECCCCEEEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCC
MRITLSLDILYFFASSWKAFAFYLVATALLLNMVRMHFRLYFNVTRENISDAMTGLYNRK
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHH
ILTSSLEQRLQRLAETGKAVFFISLDLDNLKVINDTLGHHEGDLAISLLAKAIKSSVRKS
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHCC
DYAIRLGGDEFCVILIDSTEETASGLADRIAKKMHSIAPDKDFRFSSGYYRMKPGDTLND
CCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEECCCCCCCH
AYKASDAQLYINKHQHHMSS
HHCCCCCEEEEECHHHCCCC
>Mature Secondary Structure
MLNIMKLHHRMLRHFIAASVIILTSSFLIYELIASDRAMTAYLHYIVQRADSSFLYDKYQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHC
NQSIAAHLMRAFATPREPISDEQKQDICRSWESMNGIYGMNLVRHTYPGLHGTLQSTSAD
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCC
CNDLAEDISLLPAFDQAVKANRHQDDYGKGLGLTEEKFHYYLDLSNRYVYFYEQIDSENF
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHEEEEEEECCCEEEEEEEECCCCE
IMNNWSFLHRGTMGIDHKILDNVFTGRTVLSSIYKDNLTGKNIMSFLTPVYRAGQLKGMV
EECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEE
LVDIDNENLYNIFYTRNRPLAWQYLNVTLSDLDSGQDIVVHKSESNLFSYVKYVQDLPGG
EEEECCCCEEEEEEECCCCEEEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCC
MRITLSLDILYFFASSWKAFAFYLVATALLLNMVRMHFRLYFNVTRENISDAMTGLYNRK
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHH
ILTSSLEQRLQRLAETGKAVFFISLDLDNLKVINDTLGHHEGDLAISLLAKAIKSSVRKS
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHCC
DYAIRLGGDEFCVILIDSTEETASGLADRIAKKMHSIAPDKDFRFSSGYYRMKPGDTLND
CCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEECCCCCCCH
AYKASDAQLYINKHQHHMSS
HHCCCCCEEEEECHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]