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The map label for this gene is gst [C]

Identifier: 218549139

GI number: 218549139

Start: 1846554

End: 1847036

Strand: Direct

Name: gst [C]

Synonym: EFER_1791

Alternate gene names: 218549139

Gene position: 1846554-1847036 (Clockwise)

Preceding gene: 218549138

Following gene: 218549142

Centisome position: 40.24

GC content: 40.17

Gene sequence:

>483_bases
GTGAAATCACCACACCCTTTTGGGAAAGTTCCTTTTTTGATAGACGAAGAAGTTTCAATAAGTGAGACTTTAGCCATATG
TACCTACCTGTGTGAAAAACATCAAAATGTCACTCTTTACCCCGCAAACTTGGTTGAAAAAGCCTCTGTTAATTCCTGGT
TAAGCTTCACCCTCACCGATTTAGAAGCTCCGGTATGGGGGTTGCTCAAACACATCACATTCACTCCAGAAAATCAACGC
TCCACAAACTTAATGAATTATCTTAGAGAAGAAGCAGCCAAGGTTATCAACCAAATTCACTTCAACACGGCTCATACTTG
GATCGCGGGAAATAATTTTACTCTAGCTGACATTTTTCTCTCACACACGTTGCAATGGGCAAAACTGTGCGGATTAGACG
TTAACACAGAAACTAACTGCTATATAGTTAGAACCCAGAGCCGACCAACTTTCGTGAAAGCTTGTGAAAAGAATAATCTT
TAA

Upstream 100 bases:

>100_bases
TTACCCTAAAAGTAGATCTCTCAGAGTACTTTGGGCACTTGAAGAAATTGGAATATCTTACGATACCGTAAGAGTTGATC
TTTTTAATCCAGATTCTAAA

Downstream 100 bases:

>100_bases
TAAAGTTTGTAACATTATGGTATTTAAGCACAGTTGTATTCCCAAATTCCGTTCCTGGCACAGAGGGGACAAACTGTAGT
AATTTACTGAATTTGCCCAC

Product: glutathione S-transferase

Products: HX; R-S-Glutathione; S-(2,4-dinitrophenyl)glutathione [C]

Alternate protein names: Glutathione S-Transferase Family Protein; Glutathione S-Transferase; Glutathione S-Transferase-Like; Glutathione S-Transferase-Like Protein; Glutathione S-Transferase Protein; Glutathione S-Transferase Domain Protein; Glutathione S-Transferase N-Terminal Domain; Glutathione S-Transferase Like Protein; Glutathione S-Transferase N-Terminal Domain Protein; Glutathione Transferase

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKSPHPFGKVPFLIDEEVSISETLAICTYLCEKHQNVTLYPANLVEKASVNSWLSFTLTDLEAPVWGLLKHITFTPENQR
STNLMNYLREEAAKVINQIHFNTAHTWIAGNNFTLADIFLSHTLQWAKLCGLDVNTETNCYIVRTQSRPTFVKACEKNNL

Sequences:

>Translated_160_residues
MKSPHPFGKVPFLIDEEVSISETLAICTYLCEKHQNVTLYPANLVEKASVNSWLSFTLTDLEAPVWGLLKHITFTPENQR
STNLMNYLREEAAKVINQIHFNTAHTWIAGNNFTLADIFLSHTLQWAKLCGLDVNTETNCYIVRTQSRPTFVKACEKNNL
>Mature_160_residues
MKSPHPFGKVPFLIDEEVSISETLAICTYLCEKHQNVTLYPANLVEKASVNSWLSFTLTDLEAPVWGLLKHITFTPENQR
STNLMNYLREEAAKVINQIHFNTAHTWIAGNNFTLADIFLSHTLQWAKLCGLDVNTETNCYIVRTQSRPTFVKACEKNNL

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18 [C]

Molecular weight: Translated: 18229; Mature: 18229

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSPHPFGKVPFLIDEEVSISETLAICTYLCEKHQNVTLYPANLVEKASVNSWLSFTLTD
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCHHHEEEEHH
LEAPVWGLLKHITFTPENQRSTNLMNYLREEAAKVINQIHFNTAHTWIAGNNFTLADIFL
HCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
SHTLQWAKLCGLDVNTETNCYIVRTQSRPTFVKACEKNNL
HHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHCCCCC
>Mature Secondary Structure
MKSPHPFGKVPFLIDEEVSISETLAICTYLCEKHQNVTLYPANLVEKASVNSWLSFTLTD
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCHHHEEEEHH
LEAPVWGLLKHITFTPENQRSTNLMNYLREEAAKVINQIHFNTAHTWIAGNNFTLADIFL
HCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
SHTLQWAKLCGLDVNTETNCYIVRTQSRPTFVKACEKNNL
HHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; Glutathione; 1-chloro-2,4-dinitrobenzene; reduced glutathione [C]

Specific reaction: RX + Glutathione = HX + R-S-Glutathione 1-chloro-2,4-dinitrobenzene + reduced glutathione = S-(2,4-dinitrophenyl)glutathione [C]

General reaction: Aryl group transfer [C]

Inhibitor: Cd2+; CibacronBlue; Co2+; Cu2+; Hematin; Hg2+; Ni2+; Sulfophthaleins; Tributyl tinacetate; Triethyl tinbromide; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA