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The map label for this gene is fabH [H]

Identifier: 218549080

GI number: 218549080

Start: 1778718

End: 1779725

Strand: Reverse

Name: fabH [H]

Synonym: EFER_1732

Alternate gene names: 218549080

Gene position: 1779725-1778718 (Counterclockwise)

Preceding gene: 218549081

Following gene: 218549079

Centisome position: 38.78

GC content: 51.59

Gene sequence:

>1008_bases
GTGGATCGACCTAATCAACCGACGATCTCCGCGGCGTTAAAAATAATCGCCACGGGGATCGCCTTACCCCCTGATAAAAT
CACTTCTCAACAACTGGATGTTCAGTTAAATAAACCAGTTGGCTATGTTGAGCGACGTTCCGGTATTTGCTGGCGCTATT
TTGCCCGCAACGACGCCAGTCAGGCCGAACTGGCGGCAGACGCATTGCATAATGCGTTATCAGCGGCGGCCTTAAAACCT
TCTGATATTGATCTGCTAATTTGTGCATCGGCCATAGCCATACAGGCATTACCCTGTAGCGCAATTCATATTCTCAAAGC
CGCAGCCATGCCCGCAGGCATTGCCGGGTTTGATATCAACAGTAGCTGTGTGAGCTTTATTTCCGCTCTGGAAGTTGCAG
CAGGATTATTAAACTGTGGGGCATACCGGCGCATTGCCATCGTCTCGGCAGATATCGCTTCACGCGGTATCGACTGGAAT
CATGAAGAGTCGTCACTCATTTTTGGTGATGGTGCAGCGTGCGCGATTGTTGAGCGGGGCGATGGTCGCAGCGGGATTAT
CGCCAGCCTGATCGAAATGTATCCCGAAGGCAGCGAACTGTGTGAAATTCGCGCTGGCGGCACACGGTGTAATCCTCGCT
CTGGCGTAAGTGACAGCGACTTTCTTTTTCATATGCAGGGAAAACCGCTGTTTCGTTTTGCTTCTTCGCTTATTGAAGAT
TATTTTTCGCGCTTACTGCAAAAAAGCGGTCTGCAACTGGCTGATATCGGTACGGTCGTTCCGCATCAGGCCAGTCATCT
TTCCCTTGAACATATGCGTAAACGGCTGCGAGTGCCGGAGTCTGCGCTCATTGATGTCTACCGTTTCTACGGCAATCAGG
TTGCGGCGTCTGTCCCCACAGCGCTGCATGAAGCGGTGATTAGCGGTCGTTTCACTAAGGATAAGCCTGCGATGTTGATT
GGCACGGCGGCGGGATTAACGCTGGCAGGTATGGTGCTTTTACCGTGA

Upstream 100 bases:

>100_bases
AAACATCGGCGGTTATACACTGCCGATTTTTCGGATTGTAGGGAAACGTACCTCATCTATATGATGGGTCCACCTATGGA
GCAGTGAAGGAGCACTGACC

Downstream 100 bases:

>100_bases
AAATCCTCGTGACGGGGGCGACCAGCGGCCTCGGGCGAAATGCTGTGCAATCTTTGTTGCAATCGGGAGTGTCGGTTGTG
GCAACAGGGCGCAATCGCGA

Product: 3-oxoacyl-[acyl-carrier-protein] synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MDRPNQPTISAALKIIATGIALPPDKITSQQLDVQLNKPVGYVERRSGICWRYFARNDASQAELAADALHNALSAAALKP
SDIDLLICASAIAIQALPCSAIHILKAAAMPAGIAGFDINSSCVSFISALEVAAGLLNCGAYRRIAIVSADIASRGIDWN
HEESSLIFGDGAACAIVERGDGRSGIIASLIEMYPEGSELCEIRAGGTRCNPRSGVSDSDFLFHMQGKPLFRFASSLIED
YFSRLLQKSGLQLADIGTVVPHQASHLSLEHMRKRLRVPESALIDVYRFYGNQVAASVPTALHEAVISGRFTKDKPAMLI
GTAAGLTLAGMVLLP

Sequences:

>Translated_335_residues
MDRPNQPTISAALKIIATGIALPPDKITSQQLDVQLNKPVGYVERRSGICWRYFARNDASQAELAADALHNALSAAALKP
SDIDLLICASAIAIQALPCSAIHILKAAAMPAGIAGFDINSSCVSFISALEVAAGLLNCGAYRRIAIVSADIASRGIDWN
HEESSLIFGDGAACAIVERGDGRSGIIASLIEMYPEGSELCEIRAGGTRCNPRSGVSDSDFLFHMQGKPLFRFASSLIED
YFSRLLQKSGLQLADIGTVVPHQASHLSLEHMRKRLRVPESALIDVYRFYGNQVAASVPTALHEAVISGRFTKDKPAMLI
GTAAGLTLAGMVLLP
>Mature_335_residues
MDRPNQPTISAALKIIATGIALPPDKITSQQLDVQLNKPVGYVERRSGICWRYFARNDASQAELAADALHNALSAAALKP
SDIDLLICASAIAIQALPCSAIHILKAAAMPAGIAGFDINSSCVSFISALEVAAGLLNCGAYRRIAIVSADIASRGIDWN
HEESSLIFGDGAACAIVERGDGRSGIIASLIEMYPEGSELCEIRAGGTRCNPRSGVSDSDFLFHMQGKPLFRFASSLIED
YFSRLLQKSGLQLADIGTVVPHQASHLSLEHMRKRLRVPESALIDVYRFYGNQVAASVPTALHEAVISGRFTKDKPAMLI
GTAAGLTLAGMVLLP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=309, Percent_Identity=28.1553398058252, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35656; Mature: 35656

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRPNQPTISAALKIIATGIALPPDKITSQQLDVQLNKPVGYVERRSGICWRYFARNDAS
CCCCCCCHHHHHHHHHHHCCCCCCHHHCCHHCCEEECCCCCHHHHCCCCEEEEECCCCCH
QAELAADALHNALSAAALKPSDIDLLICASAIAIQALPCSAIHILKAAAMPAGIAGFDIN
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
SSCVSFISALEVAAGLLNCGAYRRIAIVSADIASRGIDWNHEESSLIFGDGAACAIVERG
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHCCCCCCCCCCCEEEECCCEEEEEECC
DGRSGIIASLIEMYPEGSELCEIRAGGTRCNPRSGVSDSDFLFHMQGKPLFRFASSLIED
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
YFSRLLQKSGLQLADIGTVVPHQASHLSLEHMRKRLRVPESALIDVYRFYGNQVAASVPT
HHHHHHHHCCCEEECCCCCCCCCCHHCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHH
ALHEAVISGRFTKDKPAMLIGTAAGLTLAGMVLLP
HHHHHHHCCCCCCCCCCEEEEEHHHHHHHCEEECC
>Mature Secondary Structure
MDRPNQPTISAALKIIATGIALPPDKITSQQLDVQLNKPVGYVERRSGICWRYFARNDAS
CCCCCCCHHHHHHHHHHHCCCCCCHHHCCHHCCEEECCCCCHHHHCCCCEEEEECCCCCH
QAELAADALHNALSAAALKPSDIDLLICASAIAIQALPCSAIHILKAAAMPAGIAGFDIN
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
SSCVSFISALEVAAGLLNCGAYRRIAIVSADIASRGIDWNHEESSLIFGDGAACAIVERG
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHCCCCCCCCCCCEEEECCCEEEEEECC
DGRSGIIASLIEMYPEGSELCEIRAGGTRCNPRSGVSDSDFLFHMQGKPLFRFASSLIED
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
YFSRLLQKSGLQLADIGTVVPHQASHLSLEHMRKRLRVPESALIDVYRFYGNQVAASVPT
HHHHHHHHCCCEEECCCCCCCCCCHHCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHH
ALHEAVISGRFTKDKPAMLIGTAAGLTLAGMVLLP
HHHHHHHCCCCCCCCCCEEEEEHHHHHHHCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA