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The map label for this gene is tdk [H]

Identifier: 218549067

GI number: 218549067

Start: 1765839

End: 1766492

Strand: Reverse

Name: tdk [H]

Synonym: EFER_1717

Alternate gene names: 218549067

Gene position: 1766492-1765839 (Counterclockwise)

Preceding gene: 218549069

Following gene: 218549065

Centisome position: 38.5

GC content: 45.26

Gene sequence:

>654_bases
TTGTATATCACCTGGGTGAGGGTTTTGTCGCCAATGGCACAACTATATTTTTACTATTCAGCAATGAATGCGGGTAAGTC
TACGGCGTTGCTGCAATCGTCTTACAATTATCAGGAACGCGGAATGCGTACTGTTGTTTATACGGCAGAAATTGACGACC
GTTTCGGTGCCGGGAAAGTAAGCTCCCGCATAGGGCTTTCATCACCAGCCAGATTGTTTAACCAAAACTCATCATTATTC
GAAGAAATTCGTGCAGAAAATGCGAAACAACCTGTCGATTGTGTTTTGGTTGATGAGTGCCAATTTTTAACCCGCCAACA
GGTTTATGATTTATCCGAAGTTGTCGATCAACTTGATATTCCAGTACTGTGTTACGGCTTACGTACAGATTTTCGTGGTG
AACTCTTCGGAGGTAGCCAATACCTGCTGGCCTGGTCAGACAAACTTGTCGAATTAAAAACTATCTGTTTCTGTGGCCGT
AAAGCAAGCATGGTGTTGCGGCTCGACCAGGAGGGGAGACCCTATAATGAAGGCGAACAGGTGGTGATAGGCGGTAATGA
ACGCTATGTCTCCGTATGTCGTAAGCACTATAAAGAAGCGCTTGCTACAGACTCTCTGGTTGCGATTCAGAAGCGTCACC
GACAAGCAGAATAA

Upstream 100 bases:

>100_bases
AACGGCACTATAGCAGCCTATTGTTCACCCAGACTAAATACACCGACATACACGCTCTGCGAGCGGGAAAACGGGCAAAA
TATGGTACACTTCTGGCAAA

Downstream 100 bases:

>100_bases
TTTATTTTGACCGTGATAAAGCTGGTGTAACGCAGGAACAGCATTGTTTCAGCGGACATCAGCTTTTTTATCGAATATAG
AATTTTCGCTGGCACCATTC

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MYITWVRVLSPMAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPARLFNQNSSLF
EEIRAENAKQPVDCVLVDECQFLTRQQVYDLSEVVDQLDIPVLCYGLRTDFRGELFGGSQYLLAWSDKLVELKTICFCGR
KASMVLRLDQEGRPYNEGEQVVIGGNERYVSVCRKHYKEALATDSLVAIQKRHRQAE

Sequences:

>Translated_217_residues
MYITWVRVLSPMAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPARLFNQNSSLF
EEIRAENAKQPVDCVLVDECQFLTRQQVYDLSEVVDQLDIPVLCYGLRTDFRGELFGGSQYLLAWSDKLVELKTICFCGR
KASMVLRLDQEGRPYNEGEQVVIGGNERYVSVCRKHYKEALATDSLVAIQKRHRQAE
>Mature_217_residues
MYITWVRVLSPMAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPARLFNQNSSLF
EEIRAENAKQPVDCVLVDECQFLTRQQVYDLSEVVDQLDIPVLCYGLRTDFRGELFGGSQYLLAWSDKLVELKTICFCGR
KASMVLRLDQEGRPYNEGEQVVIGGNERYVSVCRKHYKEALATDSLVAIQKRHRQAE

Specific function: Phosphorylates both thymidine and deoxyuridine [H]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=204, Percent_Identity=92.156862745098, Blast_Score=392, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 24760; Mature: 24760

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYITWVRVLSPMAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKV
CEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHCCCEEEEEEEECCCCCCCCCH
SSRIGLSSPARLFNQNSSLFEEIRAENAKQPVDCVLVDECQFLTRQQVYDLSEVVDQLDI
HHCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
PVLCYGLRTDFRGELFGGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQEGRPYNEGEQ
CEEEEECCCCCCCEECCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCE
VVIGGNERYVSVCRKHYKEALATDSLVAIQKRHRQAE
EEECCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCC
>Mature Secondary Structure
MYITWVRVLSPMAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKV
CEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHCCCEEEEEEEECCCCCCCCCH
SSRIGLSSPARLFNQNSSLFEEIRAENAKQPVDCVLVDECQFLTRQQVYDLSEVVDQLDI
HHCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
PVLCYGLRTDFRGELFGGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQEGRPYNEGEQ
CEEEEECCCCCCCEECCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCE
VVIGGNERYVSVCRKHYKEALATDSLVAIQKRHRQAE
EEECCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10222209; 11206551; 11258796 [H]