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The map label for this gene is sohB [H]

Identifier: 218549037

GI number: 218549037

Start: 1732163

End: 1733212

Strand: Reverse

Name: sohB [H]

Synonym: EFER_1685

Alternate gene names: 218549037

Gene position: 1733212-1732163 (Counterclockwise)

Preceding gene: 218549040

Following gene: 218549035

Centisome position: 37.77

GC content: 48.1

Gene sequence:

>1050_bases
GTGGAATTGTTGTCTGAATATGGGCTTTTTTTAGCGAAAATCGTGACAGTTGTGCTGGCTATCGCCGCGATAGCCGCCAT
TATTGTCAATGTTGCGCAAAAGAATAAACGTCAGCGTGGAGAGCTGCGTATTACCCGGTTGAGCGAACAATATGAGGAGA
TGAAGGAAGAGCTGGCTACGGCGTTGATGGATGCACATCAACAGAAAATCTGGCACAAGGCGCAGAAGAAAAAACATAAA
CAAGAGGCCAAACTGGCAAAAGCGAAAGCCAAACAAGGTGAGACGCTTAGTTCAGATAAACCACGAGTATGGGTTCTGGA
CTTTAAAGGCAGTATGGATGCCCATGAAGTCACCGCTTTACGGGAAGAAATAACGGCTGTACTGGCAGTATATAAACCGC
AGGATCAAGTGGTGGTTCGCCTGGAAAGCCCTGGCGGCGTGGTACACGGTTATGGTTTGGCAGCGTCACAGTTACAGCGG
TTGCGAGATCACAATATTCCTTTGACTGTCACTGTTGATAAAGTAGCCGCCAGCGGTGGTTATATGATGGCCTGCGTGGC
AGATAAAATTGTCTCTGCACCGTTTGCTATTGTTGGCTCCATTGGCGTGGTGGCGCAATTGCCTAACTTTAATCGCTTCC
TGAAAAGCAAAGATATTGATATTGAGCTTCACACTGCGGGGCAATATAAACGCACATTGACGCTGCTGGGTGAAAATACC
GAAGAAGGGCGCGAGAAATTCCGCGAAGAGCTGAACGAAACGCATCTGCTCTTTAAAGATTTTGTGAAGCGTATGCGTCC
GTCTCTGGATATTGATCAGGTGGCAACAGGTGAACACTGGTATGGTCAACAGGCGCTGGAAAAAGGTCTGGTGGATGAAA
TTAATACCAGTGATGACGTAATTCTCGGCCTGATGGATGGTCGTGAAGTGGTCAATGTTCGTTATATGCAGCGCAAAAAG
CTGCTGGACAGATTCACCGGAAGCGCAGCTGAAAGTGCGGACCGTCTGTTGCTACGCTGGTGGCAGCGTGGGCAAAAACC
ATTGATGTAA

Upstream 100 bases:

>100_bases
ATTTTGGCATTATTTGATTTGAGAAGATTCCCTGCGAGACGATGAAAAAGACCTGTTGTAAACTGAGCGAAAATTGCGTT
GATAAACCAAGGTGGGACTT

Downstream 100 bases:

>100_bases
AAACAAACGCGAGGTTCAGGCCTCGCGTTTTGCTTTAATCAACAAGGTGATATTTTTCAGACAGTACGTGCGCGAGATGT
TTAAACATATTAAATACGGC

Product: periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQKNKRQRGELRITRLSEQYEEMKEELATALMDAHQQKIWHKAQKKKHK
QEAKLAKAKAKQGETLSSDKPRVWVLDFKGSMDAHEVTALREEITAVLAVYKPQDQVVVRLESPGGVVHGYGLAASQLQR
LRDHNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQLPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENT
EEGREKFREELNETHLLFKDFVKRMRPSLDIDQVATGEHWYGQQALEKGLVDEINTSDDVILGLMDGREVVNVRYMQRKK
LLDRFTGSAAESADRLLLRWWQRGQKPLM

Sequences:

>Translated_349_residues
MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQKNKRQRGELRITRLSEQYEEMKEELATALMDAHQQKIWHKAQKKKHK
QEAKLAKAKAKQGETLSSDKPRVWVLDFKGSMDAHEVTALREEITAVLAVYKPQDQVVVRLESPGGVVHGYGLAASQLQR
LRDHNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQLPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENT
EEGREKFREELNETHLLFKDFVKRMRPSLDIDQVATGEHWYGQQALEKGLVDEINTSDDVILGLMDGREVVNVRYMQRKK
LLDRFTGSAAESADRLLLRWWQRGQKPLM
>Mature_349_residues
MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQKNKRQRGELRITRLSEQYEEMKEELATALMDAHQQKIWHKAQKKKHK
QEAKLAKAKAKQGETLSSDKPRVWVLDFKGSMDAHEVTALREEITAVLAVYKPQDQVVVRLESPGGVVHGYGLAASQLQR
LRDHNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQLPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENT
EEGREKFREELNETHLLFKDFVKRMRPSLDIDQVATGEHWYGQQALEKGLVDEINTSDDVILGLMDGREVVNVRYMQRKK
LLDRFTGSAAESADRLLLRWWQRGQKPLM

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=349, Percent_Identity=91.1174785100286, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1788064, Length=170, Percent_Identity=30, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 39328; Mature: 39328

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQKNKRQRGELRITRLSEQYEEMKEELAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALMDAHQQKIWHKAQKKKHKQEAKLAKAKAKQGETLSSDKPRVWVLDFKGSMDAHEVTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHH
REEITAVLAVYKPQDQVVVRLESPGGVVHGYGLAASQLQRLRDHNIPLTVTVDKVAASGG
HHHHHHHHHHCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCCEEEEEHHHHCCCC
YMMACVADKIVSAPFAIVGSIGVVAQLPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENT
EEHHHHHHHHHHCCHHHHHCHHHHHCCCCHHHHHHCCCCCEEEECCCCCHHEEEEECCCC
EEGREKFREELNETHLLFKDFVKRMRPSLDIDQVATGEHWYGQQALEKGLVDEINTSDDV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHCCCHHHCCCCCCE
ILGLMDGREVVNVRYMQRKKLLDRFTGSAAESADRLLLRWWQRGQKPLM
EEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQKNKRQRGELRITRLSEQYEEMKEELAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALMDAHQQKIWHKAQKKKHKQEAKLAKAKAKQGETLSSDKPRVWVLDFKGSMDAHEVTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHH
REEITAVLAVYKPQDQVVVRLESPGGVVHGYGLAASQLQRLRDHNIPLTVTVDKVAASGG
HHHHHHHHHHCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCCEEEEEHHHHCCCC
YMMACVADKIVSAPFAIVGSIGVVAQLPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENT
EEHHHHHHHHHHCCHHHHHCHHHHHCCCCHHHHHHCCCCCEEEECCCCCHHEEEEECCCC
EEGREKFREELNETHLLFKDFVKRMRPSLDIDQVATGEHWYGQQALEKGLVDEINTSDDV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHCCCHHHCCCCCCE
ILGLMDGREVVNVRYMQRKKLLDRFTGSAAESADRLLLRWWQRGQKPLM
EEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]