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The map label for this gene is sufB

Identifier: 218548731

GI number: 218548731

Start: 1405509

End: 1406996

Strand: Direct

Name: sufB

Synonym: EFER_1369

Alternate gene names: 218548731

Gene position: 1405509-1406996 (Clockwise)

Preceding gene: 218548730

Following gene: 218548732

Centisome position: 30.63

GC content: 51.88

Gene sequence:

>1488_bases
ATGTCTCGTAATACTGAAGCAACTGACGATGTCAAAACCTGGACCGGCGGCCCGCTGAATTATAAAGAAGGGTTCTTCAC
CCAGTTAGCCACCGATGAGCTGGCAAAGGGGATAAACGAAGAGGTGGTGCGCGCAATTTCGGCGAAGCGTAATGAGCCGG
AGTGGATGCTGGAGTTTCGTCTCAATGCTTATCGCGCATGGCTGGAGATGGAAGAGCCGCACTGGCTTAAAGCGCACTAC
GACAAGCTGAATTATCAGGATTACAGTTACTACTCAGCACCATCGTGCGGTAATTGTGACGACACTTGCGCGTCGGAACC
CGGCGCGGTGCAGCAAACTGGCGCGAACGCCTTTTTAAGTAAAGAGGTGGAGGCGGCGTTTGAGCAGTTGGGCGTTCCCG
TACGGGAAGGCAAAGAAGTGGCAGTGGATGCCATTTTCGACTCTGTTTCGGTTGCCACCACTTATCGCGAAAAACTGGCG
GAGCAGGGAATTATTTTTTGTTCCTTTGGCGAGGCGATCCACGATCACCCGGAACTGGTGCGTAAATATCTCGGCACCGT
GGTGCCGGGGAATGACAACTTCTTTGCCGCGCTTAATGCGGCGGTGGCCTCTGACGGTACATTTATTTATGTGCCTAAAG
GCGTGCGCTGCCCGATGGAACTTTCCACGTATTTCCGTATTAACGCGGAAAAAACCGGGCAGTTTGAGCGCACCATTCTG
GTGGCCGACGAAGACAGCTACGTCAGCTACATTGAAGGATGTTCCGCTCCGGTGCGCGACAGCTATCAGTTACACGCGGC
GGTGGTGGAAGTCATCATCCATAAAAACGCCGAGGTGAAATATTCCACGGTACAAAACTGGTTCCCTGGCGATAACAACA
CCGGCGGTATTCTCAACTTCGTCACCAAGCGTGCTTTGTGCGAAGGCGAAAACAGCAAAATGTCATGGACGCAATCAGAA
ACCGGGTCAGCGATTACGTGGAAATATCCCAGTTGCATTTTGCGCGGCGATAACTCCATCGGTGAGTTTTACTCAGTGGC
ACTGACCAGCGGTCATCAGCAGGCGGATACCGGCACCAAGATGATCCACATTGGTAAAAACACCAAATCGACCATTATCT
CTAAAGGGATCTCAGCCGGACACAGCCAGAACAGTTATCGCGGCTTAGTGAAAATCATGCCGACGGCAACCAATGCACGT
AACTTCACCCAGTGCGACTCAATGCTGATAGGCGCTAATTGTGGGGCGCATACTTTCCCGTATGTCGAATGTCGCAATAA
CAGCGCGCAACTGGAGCACGAGGCAACGACATCACGTATTGGTGAAGATCAACTGTTTTACTGCCTGCAACGCGGGATCA
GCGAAGAAGACGCCATCTCGATGATTGTTAACGGCTTTTGCAAAGATGTGTTCTCGGAACTGCCGCTGGAATTTGCCGTT
GAAGCACAAAAACTCCTCGCCATCAGTCTTGAACACAGCGTCGGATAA

Upstream 100 bases:

>100_bases
ATTTCGTTCGTGAAGGACTTAATCAGATATTCAAATTTCACAACCCTAAAGCCCAGAATGAATGTGGCTGTGGCGAAAGC
TTTGGGGTATAGGCGGTACT

Downstream 100 bases:

>100_bases
GGAATAAACATGTTAAGTATTAAAGATTTACACGTCAGCGTGGAAGATAAAACTATCCTGCGTGGGTTAAGCCTCGACGT
TCGTCCCGGCGAAGTTCACG

Product: cysteine desulfurase activator complex subunit SufB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHY
DKLNYQDYSYYSAPSCGNCDDTCASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSE
TGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNAR
NFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EAQKLLAISLEHSVG

Sequences:

>Translated_495_residues
MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHY
DKLNYQDYSYYSAPSCGNCDDTCASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSE
TGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNAR
NFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EAQKLLAISLEHSVG
>Mature_494_residues
SRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHYD
KLNYQDYSYYSAPSCGNCDDTCASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLAE
QGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTILV
ADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSET
GSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNARN
FTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAVE
AQKLLAISLEHSVG

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family

Homologues:

Organism=Escherichia coli, GI87081955, Length=495, Percent_Identity=100, Blast_Score=1039, Evalue=0.0,
Organism=Escherichia coli, GI1787971, Length=153, Percent_Identity=26.797385620915, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUFB_ECOLI (P77522)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C64926
- RefSeq:   AP_002303.1
- RefSeq:   NP_416198.2
- ProteinModelPortal:   P77522
- DIP:   DIP-10938N
- IntAct:   P77522
- STRING:   P77522
- EnsemblBacteria:   EBESCT00000004004
- EnsemblBacteria:   EBESCT00000017288
- GeneID:   945753
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5273
- KEGG:   eco:b1683
- EchoBASE:   EB3723
- EcoGene:   EG13965
- eggNOG:   COG0719
- GeneTree:   EBGT00050000009092
- HOGENOM:   HBG711081
- OMA:   SQCDSML
- ProtClustDB:   PRK11814
- BioCyc:   EcoCyc:G6909-MONOMER
- Genevestigator:   P77522
- InterPro:   IPR010231
- InterPro:   IPR000825
- TIGRFAMs:   TIGR01980

Pfam domain/function: PF01458 UPF0051

EC number: NA

Molecular weight: Translated: 54746; Mature: 54614

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEH
LNAYRAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDTCASEPGAVQQTGANAFLS
HHHHHHHEECCCCCHHHHHHHCCCCCCCCEECCCCCCCCCHHHCCCCCCCHHCCCHHHHH
KEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLAEQGIIFCSFGEAIHDHPELV
HHHHHHHHHHCCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCHHHH
RKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
HHHHCEECCCCCCEEEEEEHHHCCCCCEEEECCCCCCCCEECEEEEEECCCCCCEEEEEE
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNF
EECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCCCCHHHHH
VTKRALCEGENSKMSWTQSETGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTK
HHHHHHHCCCCCCEEEECCCCCCEEEEECCCEEEECCCCCCHHEEEEECCCCCCCCCCCE
MIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNARNFTQCDSMLIGANCGAHTFP
EEEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCEEEECCCCCCCCC
YVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EEEECCCCCCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
EAQKLLAISLEHSVG
HHHHHHEEEECCCCC
>Mature Secondary Structure 
SRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEH
LNAYRAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDTCASEPGAVQQTGANAFLS
HHHHHHHEECCCCCHHHHHHHCCCCCCCCEECCCCCCCCCHHHCCCCCCCHHCCCHHHHH
KEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLAEQGIIFCSFGEAIHDHPELV
HHHHHHHHHHCCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCHHHH
RKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
HHHHCEECCCCCCEEEEEEHHHCCCCCEEEECCCCCCCCEECEEEEEECCCCCCEEEEEE
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNF
EECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCCCCHHHHH
VTKRALCEGENSKMSWTQSETGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTK
HHHHHHHCCCCCCEEEECCCCCCEEEEECCCEEEECCCCCCHHEEEEECCCCCCCCCCCE
MIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNARNFTQCDSMLIGANCGAHTFP
EEEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCEEEECCCCCCCCC
YVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EEEECCCCCCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
EAQKLLAISLEHSVG
HHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040