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The map label for this gene is chbC [H]

Identifier: 218548694

GI number: 218548694

Start: 1366322

End: 1367680

Strand: Direct

Name: chbC [H]

Synonym: EFER_1330

Alternate gene names: 218548694

Gene position: 1366322-1367680 (Clockwise)

Preceding gene: 218548693

Following gene: 218548695

Centisome position: 29.78

GC content: 46.73

Gene sequence:

>1359_bases
ATGAGTAATGTTATTGCTTCACTTGAAAAGGTACTCCTTCCTTTTGCTGTAAAAATAGGAAAGCAGCCACATATTAATGC
AATTAAAAACGGTTTTATTCGCTTAATGCCGTTAACCCTTGCAGGGGCTATGTTTGTATTAATAAACAACGTTTTCCTGA
GCTTTGGGGAGGGGTCATTTTTTTATTCCTTAGGTATTCGCCTGGATGCTTCTACCATCGAAACACTGAATGGTTTGAAA
GGCATTGGCGGAAACGTCTACAACGGTACATTAGGCATTATGTCGTTAATGGCGCCGTTTTTTATCGGTATGGCGCTGGC
AGAAGAGCGTAAAGTTGATGCGCTGGCCGCCGGTTTATTATCGGTTGCGGCATTTATGACCGTTACACCTTATAGCGTAG
GTGAAGCTTATGCTGTTGGTGCAAACTGGTTAGGTGGTGCCAATATTATCTCCGGCATTATTATTGGTCTGGTGGTTGCA
GAAATGTTTACCTTTGTTGTTCGCCGCAACTGGGTTATTCGCCTGCCTGACAGTGTGCCAGCTTCGGTGTCGCGTTCTTT
CTCGGCATTGATTCCGGGCTTTATTATCCTTTCTTTTATGGGAATTATTGCCTGGGCGCTAAATAGCTGGGGGACAAACT
TCCACCAAATCATTATGGACTCTATCTCCACGCCTCTGGCTTCAATGGGTGCGGTGGTTGGCTGGGCGTATGTGATTTTT
GTTCCGCTGCTGTGGTTCTTTGGTATTCACGGTTCACTGGCATTAACTGCGCTGGACAGCGGTATCATGACTCCATGGGC
ATTGGAAAACATCTCGATTTATCAGCAATATGGTTCCGTTGCTGCAGCTGTCGAAGCGGGTAAGACGTTCCATGTTTGGG
CGAAACCGATGCTTGACTCCTACATCTTCCTTGGTGGTAGTGGTGCAACTCTCGGGCTGATTATTGCTATCTTTATCGCT
TCCCGCCGCGCTGATTATCGTTCGGTGGCTAAACTGGCGCTGCCATCAGGTATCTTCCAGATTAACGAACCGATTCTGTT
TGGCCTGCCAATTATTATGAACCCGGTAATGTTTATTCCGTTTGTTCTGGTGCAACCGATTCTGGCAGCAATTACCCTGG
TTGCTTACTACACCGGCATTATTCCACCTATCACTAACATCGCACCGTGGACCATGCCAACCGGACTGGGCGCATTCTTT
AACACTAATGGTAGTGTTGCCGCTCTGCTGGTCGCACTCTTTAACCTCGGTGTCGCGACGCTGGTCTACCTGCCATTTGT
GGTAGTCGCTAACAAAGCACAGAACGTCATTGATGAAGAAGAGAGCGAAGAAGATATCGCTAACGCACTGAAATTTTAA

Upstream 100 bases:

>100_bases
AGCTGCTGCTAATTAATTATATTTTACATTTTTCCCGTCAAAGAGTTATTTCATAAACTTTCACCGCAATATTTATTGCG
GTTTTATAGGGTATTTTTCT

Downstream 100 bases:

>100_bases
TTGTCACCGGCAGTGGGAAACCGCTGCCGGTAAGAATAGAGAGGAACAATGTATGATGGATCTCGACAATATTCCTGATG
CGCCAACTGAAGCAGAAGAG

Product: PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Chb; PTS system N,N'-diacetylchitobiose-specific EIIC component [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSNVIASLEKVLLPFAVKIGKQPHINAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLK
GIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
EMFTFVVRRNWVIRLPDSVPASVSRSFSALIPGFIILSFMGIIAWALNSWGTNFHQIIMDSISTPLASMGAVVGWAYVIF
VPLLWFFGIHGSLALTALDSGIMTPWALENISIYQQYGSVAAAVEAGKTFHVWAKPMLDSYIFLGGSGATLGLIIAIFIA
SRRADYRSVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLVAYYTGIIPPITNIAPWTMPTGLGAFF
NTNGSVAALLVALFNLGVATLVYLPFVVVANKAQNVIDEEESEEDIANALKF

Sequences:

>Translated_452_residues
MSNVIASLEKVLLPFAVKIGKQPHINAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLK
GIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
EMFTFVVRRNWVIRLPDSVPASVSRSFSALIPGFIILSFMGIIAWALNSWGTNFHQIIMDSISTPLASMGAVVGWAYVIF
VPLLWFFGIHGSLALTALDSGIMTPWALENISIYQQYGSVAAAVEAGKTFHVWAKPMLDSYIFLGGSGATLGLIIAIFIA
SRRADYRSVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLVAYYTGIIPPITNIAPWTMPTGLGAFF
NTNGSVAALLVALFNLGVATLVYLPFVVVANKAQNVIDEEESEEDIANALKF
>Mature_451_residues
SNVIASLEKVLLPFAVKIGKQPHINAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKG
IGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVAE
MFTFVVRRNWVIRLPDSVPASVSRSFSALIPGFIILSFMGIIAWALNSWGTNFHQIIMDSISTPLASMGAVVGWAYVIFV
PLLWFFGIHGSLALTALDSGIMTPWALENISIYQQYGSVAAAVEAGKTFHVWAKPMLDSYIFLGGSGATLGLIIAIFIAS
RRADYRSVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLVAYYTGIIPPITNIAPWTMPTGLGAFFN
TNGSVAALLVALFNLGVATLVYLPFVVVANKAQNVIDEEESEEDIANALKF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=452, Percent_Identity=94.2477876106195, Blast_Score=854, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 48360; Mature: 48229

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVIASLEKVLLPFAVKIGKQPHINAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSF
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHCCCCCE
FYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLL
EEEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVAEMFTFVVRRNWVIRLPDSVP
HHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
ASVSRSFSALIPGFIILSFMGIIAWALNSWGTNFHQIIMDSISTPLASMGAVVGWAYVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VPLLWFFGIHGSLALTALDSGIMTPWALENISIYQQYGSVAAAVEAGKTFHVWAKPMLDS
HHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCC
YIFLGGSGATLGLIIAIFIASRRADYRSVAKLALPSGIFQINEPILFGLPIIMNPVMFIP
EEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEECCCHHCCCHHHHHHHHHHH
FVLVQPILAAITLVAYYTGIIPPITNIAPWTMPTGLGAFFNTNGSVAALLVALFNLGVAT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
LVYLPFVVVANKAQNVIDEEESEEDIANALKF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SNVIASLEKVLLPFAVKIGKQPHINAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSF
CHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHCCCCCE
FYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLL
EEEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVAEMFTFVVRRNWVIRLPDSVP
HHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
ASVSRSFSALIPGFIILSFMGIIAWALNSWGTNFHQIIMDSISTPLASMGAVVGWAYVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VPLLWFFGIHGSLALTALDSGIMTPWALENISIYQQYGSVAAAVEAGKTFHVWAKPMLDS
HHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCC
YIFLGGSGATLGLIIAIFIASRRADYRSVAKLALPSGIFQINEPILFGLPIIMNPVMFIP
EEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEECCCHHCCCHHHHHHHHHHH
FVLVQPILAAITLVAYYTGIIPPITNIAPWTMPTGLGAFFNTNGSVAALLVALFNLGVAT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
LVYLPFVVVANKAQNVIDEEESEEDIANALKF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 2092358; 9405618; 10913117 [H]