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The map label for this gene is torA [H]

Identifier: 218548560

GI number: 218548560

Start: 1233710

End: 1236256

Strand: Direct

Name: torA [H]

Synonym: EFER_1192

Alternate gene names: 218548560

Gene position: 1233710-1236256 (Clockwise)

Preceding gene: 218548559

Following gene: 218548561

Centisome position: 26.89

GC content: 54.73

Gene sequence:

>2547_bases
ATGAACAATAACGATCTCTTTCAGGCATCACGTCGACGTTTTCTGGCACAACTCGGCGGCTTAACTGTCGCCGGGATGCT
GGGGTCGTCATTGTTAACGCCGCGCCGTGCGACTGCGGCGCAAGCGGCGACCGAGGCGGTCACCTCGAAAGAGGGCATTC
TGACCGGGTCGCACTGGGGGGCTATCCGCGCGACGGTGAAGGATGGTCGCTTTGTGGCGGCAAAACCATTCGAACTGGAT
AAATATCCGTCGAAAATGATCGCCGGATTGCCGGATCACGTACACAATGCGGCGCGTATTCGTTATCCGATGGTACGCGT
GGACTGGCTACGTAAGCGCCATCTGAGCGACACATCTCAGCGTGGCGATAACCGGTTCGTGCGCGTGAGCTGGGATGAAG
CCCTCGACATGTTCTATGAAGAGCTGGAACGTGTGCAGAAAACGCACGGGCCGAGTGCCTTACTGACCGCCAGTGGTTGG
CAGTCGACGGGGATGTTCCATAACGCGTCGGGGATGTTGGCGAAAGCGATTGCCTTACATGGTAATAGCGTTGGTACGGG
TGGGGATTACTCCACCGGTGCTGCGCAGGTGATCCTGCCGCGTGTAGTTGGCTCAATGGAAGTGTATGAACAGCAAACCT
CCTGGCCGCTGGTATTGCAGAACAGCAAAACCATTGTGCTGTGGGGCTCCGATTTGCTGAAAAACCAGCAAGCGAACTGG
TGGTGCCCGGATCACGATGTTTATGAATATTACGCGCAGTTGAAAGCGAAAGTCGCCGCCGGTGAAATTCAGGTCATCAG
CATCGATCCGGTTGTTACATCCACTCATGAGTATCTGGGACGCGAGCATGTGAAGCACATTGCGGTTAACCCGCAAACTG
ACGTGCCGCTGCAACTGGCGCTGGCGCATACGTTGTACAGCGAAAACCTGTACGACAAAAACTTCCTCGCTAACTACTGT
GTGGGTTTTGAGCAGTTCCTGCCCTATCTGCTGGGCGAGAAAGACGGTCAGCCGAAAGATGCCGCATGGGCTGAAAAACT
GACTGGCATTGATGCCGAAACCATTCGTGGACTGGCGCGGCAGATGGCGGCGAACAGAACGCAGATTATTGCTGGTTGGT
GCGTACAGCGTATGCAGCACGGTGAACAGTGGGCGTGGATGATTGTGGTTCTGGCGGCGATGCTGGGGCAAATTGGCCTG
CCGGGTGGTGGCTTCGGTTTTGGCTGGCACTATAACGGCGCAGGCACGCCGGGGCGTAAAGGCGTTATTCTGAGTGGTTT
CTCCGGCTCTACGTCGATTCCACCTGTTCACGACAACAGCGACTACCAAGGCTATAGCAGCACTATTCCGATTGCCCGTT
TTGTCGATGCGATCCTCGAACCGGGAAAAGTGATCAACTGGAATGGTAAATCGGTAAAACTGCCACCGCTGAAAATGTGT
ATTTTTGCCGGAACTAACCCGTTACATCGTCATCAGCAGATTAACCGCATTATCGAAGGCTGGCGCAAGCTGGAAACGGT
TATCGCTATAGATAATCAGTGGACCTCAACCTGCCGCTTTGCCGATATCGTACTGCCTGCGACCACGCAGTTTGAGCGTA
ACGATCTCGACCAGTACGGTAACCACTCTAACCGTGGGATCATCGCCATGAAACAGGTGGTGCCGCCGCAGTTTGAGGCG
CGCAACGACTTTGATATTTTCCGCGAGCTGTGCCGTCGCTTTAATCGTGAAGAAGCCTTTACCGAAGGGCTGGACGAAAT
GGGCTGGCTGAAACGCATCTGGCAGGAAGGTGTACAACAGGGCAAAGGACGCGGTGTTCATCTACCAGCGTTTGATGACT
TCTGGAATAAGAAAGAGTACGTCGAGTTTGACCATCCGCAGATGTTTGTTCGCCACCAGGCATTCCGCGAAGATCCGGAT
CTCGAACCGCTGGGCACGCCGAGTGGCCTGATTGAGATCTACTCAAAAACCATCGCCGATATGAACTACGACGATTGTCA
GGGGCATCCGATGTGGTTTGAGAAAATCGAACGCTCCCACGGTGGGCCCGGCTCGCAGAAGTATCCGTTGCATCTGCAAT
CTGTGCATCCGGATTTCCGACTTCACTCGCAGTTATGTGAGTCGGAAACTTTGCGTCAGCAATATACGGTTGCGGGTAAA
GAGCCAGTATTTATTAGCCCGCAGGATGCCAGTGCGCGCGGTATTCGTAACGGTGATGTGGTGCGCGTCTTTAACGCTCG
TGGTCAGGTGTTGGCTGGAGCAGTGGTTTCTGACCGCTATGCACCCGGCGTGGCACGAATTCACGAAGGGGCATGGTACG
ATCCAGATAAAGGCGGTGAGCCTGGTGCGCTGTGCAAATACGGTAACCCCAACGTGTTGACTATCGACATCGGTACTTCG
CAGCTGGCGCAGGCGACCAGTGCGCATACCACGCTGGTGGAAATTGAGAAGTACAACGGAACAGTGGAGCAGGTGACGGC
GTTTAATGGCCCCGTTGAGATGGTGGCGCAGTGCGAATATGTTCCCGCGTCGCAGGTGAAATCATGA

Upstream 100 bases:

>100_bases
GCCTCGATAAACGTGAAGAACGCACCTTGCTGAAATATCTGCAAATGAATGCGTCTGATACCGCAGGTAAGGCTCACGGC
GATAAGAAGGAAGAAAAATA

Downstream 100 bases:

>100_bases
CCACGCTGACAGCACAACAGATTGCCTGTGTCTACGCCTGGCTGGCGCAGTTGTTCTCCCGTGAGCTGGACGATGAACAA
CTGACGCAGATCGCCAGTGC

Product: trimethylamine N-oxide (TMAO) reductase I, catalytic subunit

Products: NA

Alternate protein names: TMAO reductase 1; Trimethylamine oxidase 1 [H]

Number of amino acids: Translated: 848; Mature: 848

Protein sequence:

>848_residues
MNNNDLFQASRRRFLAQLGGLTVAGMLGSSLLTPRRATAAQAATEAVTSKEGILTGSHWGAIRATVKDGRFVAAKPFELD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
WCPDHDVYEYYAQLKAKVAAGEIQVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYC
VGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYQGYSSTIPIARFVDAILEPGKVINWNGKSVKLPPLKMC
IFAGTNPLHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEA
RNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNKKEYVEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
EPVFISPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTS
QLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS

Sequences:

>Translated_848_residues
MNNNDLFQASRRRFLAQLGGLTVAGMLGSSLLTPRRATAAQAATEAVTSKEGILTGSHWGAIRATVKDGRFVAAKPFELD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
WCPDHDVYEYYAQLKAKVAAGEIQVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYC
VGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYQGYSSTIPIARFVDAILEPGKVINWNGKSVKLPPLKMC
IFAGTNPLHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEA
RNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNKKEYVEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
EPVFISPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTS
QLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS
>Mature_848_residues
MNNNDLFQASRRRFLAQLGGLTVAGMLGSSLLTPRRATAAQAATEAVTSKEGILTGSHWGAIRATVKDGRFVAAKPFELD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
WCPDHDVYEYYAQLKAKVAAGEIQVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYC
VGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYQGYSSTIPIARFVDAILEPGKVINWNGKSVKLPPLKMC
IFAGTNPLHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEA
RNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNKKEYVEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
EPVFISPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTS
QLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787231, Length=848, Percent_Identity=98.8207547169811, Blast_Score=1753, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=828, Percent_Identity=44.3236714975845, Blast_Score=669, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=791, Percent_Identity=42.8571428571429, Blast_Score=617, Evalue=1e-177,
Organism=Escherichia coli, GI87081797, Length=760, Percent_Identity=31.9736842105263, Blast_Score=302, Evalue=6e-83,
Organism=Escherichia coli, GI1787870, Length=865, Percent_Identity=29.1329479768786, Blast_Score=273, Evalue=3e-74,
Organism=Escherichia coli, GI171474008, Length=850, Percent_Identity=28.9411764705882, Blast_Score=258, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 94460; Mature: 94460

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2 ; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNDLFQASRRRFLAQLGGLTVAGMLGSSLLTPRRATAAQAATEAVTSKEGILTGSHWG
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCC
AIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQ
EEEEEECCCEEEEECCCCCCCCHHHHHHCCCHHHCCHHHHCCCHHHHHHHHHHHCCCHHH
RGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALH
CCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCHHHHHHHHC
GNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECHHHHCCCCCCC
WCPDHDVYEYYAQLKAKVAAGEIQVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLA
CCCCCHHHHHHHHHHHHEECCEEEEEEECCCHHHHHHHHHHHHHHEEECCCCCCCCHHHH
LAHTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLAR
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
QMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRK
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
GVILSGFSGSTSIPPVHDNSDYQGYSSTIPIARFVDAILEPGKVINWNGKSVKLPPLKMC
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCEEECCHHEEE
IFAGTNPLHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYG
EEECCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHC
NHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQ
CCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHH
GKGRGVHLPAFDDFWNKKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIAD
CCCCEEECCCCHHHCCCCCCEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
EPVFISPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGE
CCEEECCCCCCCCCCCCCCEEEEECCCCCEEECHHHHCCCCCCHHHHCCCCCCCCCCCCC
PGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEY
CCCEEECCCCCEEEEECCHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCHHHHHHCCC
VPASQVKS
CCHHHCCC
>Mature Secondary Structure
MNNNDLFQASRRRFLAQLGGLTVAGMLGSSLLTPRRATAAQAATEAVTSKEGILTGSHWG
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCC
AIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQ
EEEEEECCCEEEEECCCCCCCCHHHHHHCCCHHHCCHHHHCCCHHHHHHHHHHHCCCHHH
RGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALH
CCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCHHHHHHHHC
GNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECHHHHCCCCCCC
WCPDHDVYEYYAQLKAKVAAGEIQVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLA
CCCCCHHHHHHHHHHHHEECCEEEEEEECCCHHHHHHHHHHHHHHEEECCCCCCCCHHHH
LAHTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLAR
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
QMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRK
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
GVILSGFSGSTSIPPVHDNSDYQGYSSTIPIARFVDAILEPGKVINWNGKSVKLPPLKMC
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCEEECCHHEEE
IFAGTNPLHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYG
EEECCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHC
NHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQ
CCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHH
GKGRGVHLPAFDDFWNKKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIAD
CCCCEEECCCCHHHCCCCCCEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
EPVFISPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGE
CCEEECCCCCCCCCCCCCCEEEEECCCCCEEECHHHHCCCCCCHHHHCCCCCCCCCCCCC
PGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEY
CCCEEECCCCCEEEEECCHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCHHHHHHCCC
VPASQVKS
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]