Click here to switch to the map view.

The map label for this gene is fliZ [H]

Identifier: 218548542

GI number: 218548542

Start: 1213505

End: 1214044

Strand: Direct

Name: fliZ [H]

Synonym: EFER_1173

Alternate gene names: 218548542

Gene position: 1213505-1214044 (Clockwise)

Preceding gene: 218548541

Following gene: 218548543

Centisome position: 26.45

GC content: 47.59

Gene sequence:

>540_bases
ATGACGGTGCAGCAAAGCAAACGACGGCCTCTGAGCCGCTACCTGAAAGACTTTAAACATAGCCAGACGCATTGTACCCA
CTGCCGCAAATTGCTCGATCGCATCACTCTTGTGCGCAGCGGGCAAATTGTTAACAAGCTGGAAATTGCTCGCCTTGATA
CCCCCATGGATGAGCCAGAGTGGCAAGAAGAACAACAACAATGGTCTGCGCTGTGCCGTTTTTGTGGTGATCTGCATTGC
AAAGCTCACAATGATTTCTTCGATATTGTGGGTTTTAAACAATTTCTGATAGAACAGGCCGAAATGAGCCATAGCTCCAT
TCGTGAGTATGTCGTGCGCCTGCGCCGCCTGGGTAATCACCTCCATCAACAACACGTTTCACGTGCGCTACTGGCAGAAG
GATATCTGGATGAAATCCTTGCGCCATGGTTACCGCAAACCAGCACCACCAATTACCTTATCGCGCTGCGTAAATATGAG
CAGTATCGATCACAAAATCCTTCTTTACAGGTTCAGAGACTGACATCTGATATATATTAA

Upstream 100 bases:

>100_bases
AGCCAGGCCATCAAACGATTACGCAGCAAACTGGGTAGGTGAATACGGTAACCACATTGCCGTCAAATGCCGCACAACGA
ATTGACTACCAGGAGTTATC

Downstream 100 bases:

>100_bases
AAATGAATAAGATGTAACGGAGTGTTTTTTGGCGCGAGTCAGAAACGCTCTACACTGATGCCGTTACTGACAACATTTGG
GGTAATTATGAAATTAGCAC

Product: flagella biosynthesis protein FliZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MTVQQSKRRPLSRYLKDFKHSQTHCTHCRKLLDRITLVRSGQIVNKLEIARLDTPMDEPEWQEEQQQWSALCRFCGDLHC
KAHNDFFDIVGFKQFLIEQAEMSHSSIREYVVRLRRLGNHLHQQHVSRALLAEGYLDEILAPWLPQTSTTNYLIALRKYE
QYRSQNPSLQVQRLTSDIY

Sequences:

>Translated_179_residues
MTVQQSKRRPLSRYLKDFKHSQTHCTHCRKLLDRITLVRSGQIVNKLEIARLDTPMDEPEWQEEQQQWSALCRFCGDLHC
KAHNDFFDIVGFKQFLIEQAEMSHSSIREYVVRLRRLGNHLHQQHVSRALLAEGYLDEILAPWLPQTSTTNYLIALRKYE
QYRSQNPSLQVQRLTSDIY
>Mature_178_residues
TVQQSKRRPLSRYLKDFKHSQTHCTHCRKLLDRITLVRSGQIVNKLEIARLDTPMDEPEWQEEQQQWSALCRFCGDLHCK
AHNDFFDIVGFKQFLIEQAEMSHSSIREYVVRLRRLGNHLHQQHVSRALLAEGYLDEILAPWLPQTSTTNYLIALRKYEQ
YRSQNPSLQVQRLTSDIY

Specific function: During the post-exponential growth phase transiently interferes with RpoS (sigma S) activity without affecting expression of RpoS itself. It is probably not an anti-sigma factor as its overexpression is detrimental in rapidly growing cells where there is

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082001, Length=183, Percent_Identity=70.4918032786885, Blast_Score=271, Evalue=2e-74,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022523
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N [H]

EC number: NA

Molecular weight: Translated: 21255; Mature: 21123

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQQSKRRPLSRYLKDFKHSQTHCTHCRKLLDRITLVRSGQIVNKLEIARLDTPMDEPE
CCCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
WQEEQQQWSALCRFCGDLHCKAHNDFFDIVGFKQFLIEQAEMSHSSIREYVVRLRRLGNH
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHQQHVSRALLAEGYLDEILAPWLPQTSTTNYLIALRKYEQYRSQNPSLQVQRLTSDIY
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TVQQSKRRPLSRYLKDFKHSQTHCTHCRKLLDRITLVRSGQIVNKLEIARLDTPMDEPE
CCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
WQEEQQQWSALCRFCGDLHCKAHNDFFDIVGFKQFLIEQAEMSHSSIREYVVRLRRLGNH
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHQQHVSRALLAEGYLDEILAPWLPQTSTTNYLIALRKYEQYRSQNPSLQVQRLTSDIY
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550423; 9097040; 9278503; 7590326 [H]