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The map label for this gene is atoS [H]

Identifier: 218548320

GI number: 218548320

Start: 963531

End: 965357

Strand: Reverse

Name: atoS [H]

Synonym: EFER_0941

Alternate gene names: 218548320

Gene position: 965357-963531 (Counterclockwise)

Preceding gene: 218548322

Following gene: 218548319

Centisome position: 21.04

GC content: 50.03

Gene sequence:

>1827_bases
ATGTACTCTCTGAAGTGGTTGTACCCTCGTCGTCTGCGCAACCAGCTCATCATGATGGCAATCCTGATGGTCATCATTCC
GACACTCTCTATTGGTTATATCGTAGAAACTGAAGGTCGGTCAGCGGTGTTATCTGAAAAAGAGAAAAAATTAGCGGCGG
TTGTGCAGTTGCTGAACGCCGCACTGGAAGATCGCTTTACGCTTTACCAACATCTGCCTCGTGAGGCACGCATCAGGGCG
CTGAATCAGGAGCTGGCTCCTGTCACTGAACGTATTACCCAGGCATTTCCCGGCGTCGGAGCGGGCTATTACCACAAAGA
ACTGGACGCAATTATCACTTATGCTCCGTCTGCACTCTATCAAAGCAATGTGGGGATTAGTATCACTCCTGATCATCCCG
GCAATATCGTCATGCATACCAATACAGCACAACTCTTTTCCGGCAGGCAAGTCCGCGGCGACATTATGAATTTCATGATC
CCTATCGAACACCAGGGCATCGTGCTGGGTTATATCTGGGCAAATGAATTAACGGAAGATATTCGTCGTCAGGCATGGAA
AATGGACGTGCGAATAATCATTGTCCTCTCAGCCGGGTTGCTGATTAGCTTGCTGTTGATTGTACTTTTTTCCCGGCGAT
TAAGCGCCAATATCGATATTATCACCGAAGGGCTGGCGACCCTGGCGCAAAATAACCCTACGCAACTACCACAGTTGCCA
GGTGAACTTGGGCAAATCAGCCGTGGTGTGAATAACCTTGCAGAAGCACTTCGTGAATCAAAGACACTGAATGACCTGAT
TATTGAAAATGCCGCCGATGCGGTTATTGCCATTGACCGACAAGGCGATGTGATCACCATGAATCCCGCCGCAGAAGCCA
TCACCGGATACAAACGTCAGGAACTGGTAGGCCAGCCTTACGCTACCCTCTTTGCCAACACCCATTTTTATAGTCCGGTT
CTTGATACGCTGGCGCACGGTATCGAACATATGGCGCTGGAAATCAGCTATCCCGGGCGCGACCGTACTATTGAAATCAG
CGCTACCACCAGCAGAATCCATGACGGACATGGTGAAATGATTGGCGCTTTAGTGATTTTCTCCGATCTGACGGCACGTA
AAGAAAGCCAACGGCGACTGGCGCAGACAGAAAGACTCGCCACCCTTGGGGAACTGATGGCGGGCGTAGCGCATGAAGTA
CGCAATCCTCTCACCGCCATCAGAGGTTACGTGCAAATCATTCGCCAGCAGACACCTCAGCCAGAACATCAGGAATATCT
GTCAATTGTACTGAACGAGATTGATTCTATTAACAAAGTTATTCAGCAGCTTTTGGATTTTTCCCGCCCGCGTAAAAGTC
AGTGGCAGCAAGTGTATCTCAAAGCCCTGATCGAAGAGACGCTGATCCTTGCCCAAACCTCCGGCGTACAGGCACGGATC
GACTTTATTACAGAACTTGACCCGTCACTCACAGCGATCGTGGCTGATCGGGAACTGCTCAAGCAGGTTATTCTCAATAT
GTTGATCAATGCCGTGCAAGCTATCACCGCACGGGGTGAAATCCGCATTCGCACATGGATGTATACAGCCAACCAGCAGG
CGATCACGATTGAAGACAACGGCTGCGGCATCGATCTGTCTCTACAGGGAAAAATCTTTGATCCCTTCTTTACCACTAAA
GCATCCGGCACAGGACTTGGACTTGCCTTAAGCCAACGAATTATTAATGCGCACCAGGGCGATATTCGCGTCGCCAGCCT
GCCCGGCTGCGGTGCCACATTCACCCTTATCTTACCGATTGATCCGCAGGAAAATTTGCCCTTATGA

Upstream 100 bases:

>100_bases
GCAATGTTCTCTCTTCTCTGGAATATGATACACCGCCGAGAAATCATCACCTTAACCTCTGATAATCGTCGTTTGTCTGA
TAATAATCCGGATACTCTGC

Downstream 100 bases:

>100_bases
ATGCCGTTTACCGAATCCTGATTGTTGACGACGAAGAGAATGTGCGTCGCATGCTATCCACCGCTTTTTCTTTGCAGGGG
TATGACACTCATTGCGCCTG

Product: sensory histidine kinase AtoS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MYSLKWLYPRRLRNQLIMMAILMVIIPTLSIGYIVETEGRSAVLSEKEKKLAAVVQLLNAALEDRFTLYQHLPREARIRA
LNQELAPVTERITQAFPGVGAGYYHKELDAIITYAPSALYQSNVGISITPDHPGNIVMHTNTAQLFSGRQVRGDIMNFMI
PIEHQGIVLGYIWANELTEDIRRQAWKMDVRIIIVLSAGLLISLLLIVLFSRRLSANIDIITEGLATLAQNNPTQLPQLP
GELGQISRGVNNLAEALRESKTLNDLIIENAADAVIAIDRQGDVITMNPAAEAITGYKRQELVGQPYATLFANTHFYSPV
LDTLAHGIEHMALEISYPGRDRTIEISATTSRIHDGHGEMIGALVIFSDLTARKESQRRLAQTERLATLGELMAGVAHEV
RNPLTAIRGYVQIIRQQTPQPEHQEYLSIVLNEIDSINKVIQQLLDFSRPRKSQWQQVYLKALIEETLILAQTSGVQARI
DFITELDPSLTAIVADRELLKQVILNMLINAVQAITARGEIRIRTWMYTANQQAITIEDNGCGIDLSLQGKIFDPFFTTK
ASGTGLGLALSQRIINAHQGDIRVASLPGCGATFTLILPIDPQENLPL

Sequences:

>Translated_608_residues
MYSLKWLYPRRLRNQLIMMAILMVIIPTLSIGYIVETEGRSAVLSEKEKKLAAVVQLLNAALEDRFTLYQHLPREARIRA
LNQELAPVTERITQAFPGVGAGYYHKELDAIITYAPSALYQSNVGISITPDHPGNIVMHTNTAQLFSGRQVRGDIMNFMI
PIEHQGIVLGYIWANELTEDIRRQAWKMDVRIIIVLSAGLLISLLLIVLFSRRLSANIDIITEGLATLAQNNPTQLPQLP
GELGQISRGVNNLAEALRESKTLNDLIIENAADAVIAIDRQGDVITMNPAAEAITGYKRQELVGQPYATLFANTHFYSPV
LDTLAHGIEHMALEISYPGRDRTIEISATTSRIHDGHGEMIGALVIFSDLTARKESQRRLAQTERLATLGELMAGVAHEV
RNPLTAIRGYVQIIRQQTPQPEHQEYLSIVLNEIDSINKVIQQLLDFSRPRKSQWQQVYLKALIEETLILAQTSGVQARI
DFITELDPSLTAIVADRELLKQVILNMLINAVQAITARGEIRIRTWMYTANQQAITIEDNGCGIDLSLQGKIFDPFFTTK
ASGTGLGLALSQRIINAHQGDIRVASLPGCGATFTLILPIDPQENLPL
>Mature_608_residues
MYSLKWLYPRRLRNQLIMMAILMVIIPTLSIGYIVETEGRSAVLSEKEKKLAAVVQLLNAALEDRFTLYQHLPREARIRA
LNQELAPVTERITQAFPGVGAGYYHKELDAIITYAPSALYQSNVGISITPDHPGNIVMHTNTAQLFSGRQVRGDIMNFMI
PIEHQGIVLGYIWANELTEDIRRQAWKMDVRIIIVLSAGLLISLLLIVLFSRRLSANIDIITEGLATLAQNNPTQLPQLP
GELGQISRGVNNLAEALRESKTLNDLIIENAADAVIAIDRQGDVITMNPAAEAITGYKRQELVGQPYATLFANTHFYSPV
LDTLAHGIEHMALEISYPGRDRTIEISATTSRIHDGHGEMIGALVIFSDLTARKESQRRLAQTERLATLGELMAGVAHEV
RNPLTAIRGYVQIIRQQTPQPEHQEYLSIVLNEIDSINKVIQQLLDFSRPRKSQWQQVYLKALIEETLILAQTSGVQARI
DFITELDPSLTAIVADRELLKQVILNMLINAVQAITARGEIRIRTWMYTANQQAITIEDNGCGIDLSLQGKIFDPFFTTK
ASGTGLGLALSQRIINAHQGDIRVASLPGCGATFTLILPIDPQENLPL

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=605, Percent_Identity=81.9834710743802, Blast_Score=1003, Evalue=0.0,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=38.3333333333333, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1790300, Length=345, Percent_Identity=28.1159420289855, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI48994928, Length=352, Percent_Identity=26.4204545454545, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081816, Length=219, Percent_Identity=30.5936073059361, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=29.4117647058824, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789149, Length=304, Percent_Identity=25.9868421052632, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082128, Length=261, Percent_Identity=28.735632183908, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788713, Length=365, Percent_Identity=24.3835616438356, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1789808, Length=215, Percent_Identity=30.2325581395349, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=29.7959183673469, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786600, Length=350, Percent_Identity=22.2857142857143, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=23.7885462555066, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67559; Mature: 67559

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSLKWLYPRRLRNQLIMMAILMVIIPTLSIGYIVETEGRSAVLSEKEKKLAAVVQLLNA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
ALEDRFTLYQHLPREARIRALNQELAPVTERITQAFPGVGAGYYHKELDAIITYAPSALY
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH
QSNVGISITPDHPGNIVMHTNTAQLFSGRQVRGDIMNFMIPIEHQGIVLGYIWANELTED
HCCCCEEECCCCCCCEEEECCHHHHHCCCHHHHHHHHHEEEECCCCEEEEEEEHHHHHHH
IRRQAWKMDVRIIIVLSAGLLISLLLIVLFSRRLSANIDIITEGLATLAQNNPTQLPQLP
HHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
GELGQISRGVNNLAEALRESKTLNDLIIENAADAVIAIDRQGDVITMNPAAEAITGYKRQ
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCEEEECCHHHHHHCHHHH
ELVGQPYATLFANTHFYSPVLDTLAHGIEHMALEISYPGRDRTIEISATTSRIHDGHGEM
HHCCCCHHHHHCCCCHHHHHHHHHHHCHHHEEEEEECCCCCCEEEEEEEHHHHHCCCHHH
IGALVIFSDLTARKESQRRLAQTERLATLGELMAGVAHEVRNPLTAIRGYVQIIRQQTPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEHQEYLSIVLNEIDSINKVIQQLLDFSRPRKSQWQQVYLKALIEETLILAQTSGVQARI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEECCCCEEEE
DFITELDPSLTAIVADRELLKQVILNMLINAVQAITARGEIRIRTWMYTANQQAITIEDN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEECC
GCGIDLSLQGKIFDPFFTTKASGTGLGLALSQRIINAHQGDIRVASLPGCGATFTLILPI
CCEEEEEECCCEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEC
DPQENLPL
CCCCCCCC
>Mature Secondary Structure
MYSLKWLYPRRLRNQLIMMAILMVIIPTLSIGYIVETEGRSAVLSEKEKKLAAVVQLLNA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
ALEDRFTLYQHLPREARIRALNQELAPVTERITQAFPGVGAGYYHKELDAIITYAPSALY
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH
QSNVGISITPDHPGNIVMHTNTAQLFSGRQVRGDIMNFMIPIEHQGIVLGYIWANELTED
HCCCCEEECCCCCCCEEEECCHHHHHCCCHHHHHHHHHEEEECCCCEEEEEEEHHHHHHH
IRRQAWKMDVRIIIVLSAGLLISLLLIVLFSRRLSANIDIITEGLATLAQNNPTQLPQLP
HHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
GELGQISRGVNNLAEALRESKTLNDLIIENAADAVIAIDRQGDVITMNPAAEAITGYKRQ
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCEEEECCHHHHHHCHHHH
ELVGQPYATLFANTHFYSPVLDTLAHGIEHMALEISYPGRDRTIEISATTSRIHDGHGEM
HHCCCCHHHHHCCCCHHHHHHHHHHHCHHHEEEEEECCCCCCEEEEEEEHHHHHCCCHHH
IGALVIFSDLTARKESQRRLAQTERLATLGELMAGVAHEVRNPLTAIRGYVQIIRQQTPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEHQEYLSIVLNEIDSINKVIQQLLDFSRPRKSQWQQVYLKALIEETLILAQTSGVQARI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEECCCCEEEE
DFITELDPSLTAIVADRELLKQVILNMLINAVQAITARGEIRIRTWMYTANQQAITIEDN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEECC
GCGIDLSLQGKIFDPFFTTKASGTGLGLALSQRIINAHQGDIRVASLPGCGATFTLILPI
CCEEEEEECCCEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEC
DPQENLPL
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]