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The map label for this gene is yfaO

Identifier: 218548299

GI number: 218548299

Start: 934309

End: 934734

Strand: Reverse

Name: yfaO

Synonym: EFER_0918

Alternate gene names: 218548299

Gene position: 934734-934309 (Counterclockwise)

Preceding gene: 218548303

Following gene: 218548297

Centisome position: 20.37

GC content: 44.37

Gene sequence:

>426_bases
GTGCGTCAAAGGACTATTGTTTGCCCATTAATTCAAAATGATGGCGCTTATCTGCTGTGTAAGATGGCGGATGATCGAGG
TGTGTTTCCAGGTCAATGGGCGTTATCGGGTGGTGGCGTTGAACCAGGTGAACGTATCGAAGACGCTCTGCGCCGGGAGA
TTCGCGAAGAATTGGGCGATAAGTTAATTCTGCAAAAGATCACCCCGTGGACATTCAGTGACGACGTGCGTATGAAAACC
TATGCTGATGGCACAAAGGAAGAGATTTACATGATCTACCTGATATTTGATTGTGTCTCCGCTAACCGGGAAATCACCAT
TAATGAAGAGTTTCAGGATTTTGCCTGGGTGAAACCACAAGATTTAGCACAATATGATTTAAATGTTGCGACACGAAAAA
CATTAAGTCTGAAAGGTTTGCTGTAA

Upstream 100 bases:

>100_bases
CTGTTATGCATGGGTTTAAAACAGCAATAGTCTTCCCTTTCATCATCACATAACTTCCCGTATTCTTTTTGTTCATTACA
TCGACATCGAGGAGTGAATC

Downstream 100 bases:

>100_bases
CAAAATATGACAGCCATTAATGGCTGTCATCGCTACTGATTAATACCTGACGAATTCTCCGTCAAGAAACAATTTTCCAT
TTTCGACATGCATCACTAAA

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGERIEDALRREIREELGDKLILQKITPWTFSDDVRMKT
YADGTKEEIYMIYLIFDCVSANREITINEEFQDFAWVKPQDLAQYDLNVATRKTLSLKGLL

Sequences:

>Translated_141_residues
MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGERIEDALRREIREELGDKLILQKITPWTFSDDVRMKT
YADGTKEEIYMIYLIFDCVSANREITINEEFQDFAWVKPQDLAQYDLNVATRKTLSLKGLL
>Mature_141_residues
MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGERIEDALRREIREELGDKLILQKITPWTFSDDVRMKT
YADGTKEEIYMIYLIFDCVSANREITINEEFQDFAWVKPQDLAQYDLNVATRKTLSLKGLL

Specific function: Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1788585, Length=141, Percent_Identity=87.9432624113475, Blast_Score=266, Evalue=5e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUDI_ESCF3 (B7LM80)

Other databases:

- EMBL:   CU928158
- RefSeq:   YP_002382090.1
- ProteinModelPortal:   B7LM80
- EnsemblBacteria:   EBESCT00000125357
- GeneID:   7122290
- GenomeReviews:   CU928158_GR
- KEGG:   efe:EFER_0918
- GeneTree:   EBGT00050000009528
- HOGENOM:   HBG741910
- ProtClustDB:   PRK15472
- BioCyc:   EFER585054:EFER_0918-MONOMER
- HAMAP:   MF_01846
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.-.- [C]

Molecular weight: Translated: 16194; Mature: 16194

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGERIEDALRREIREELGD
CCCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCH
KLILQKITPWTFSDDVRMKTYADGTKEEIYMIYLIFDCVSANREITINEEFQDFAWVKPQ
HEEHHHCCCCCCCCCCEEEEECCCCCHHEEEEEEEEEHHCCCCEEEECCCCCCCCCCCCH
DLAQYDLNVATRKTLSLKGLL
HHHHHCCCHHHCEEEEEECCC
>Mature Secondary Structure
MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGERIEDALRREIREELGD
CCCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCH
KLILQKITPWTFSDDVRMKTYADGTKEEIYMIYLIFDCVSANREITINEEFQDFAWVKPQ
HEEHHHCCCCCCCCCCEEEEECCCCCHHEEEEEEEEEHHCCCCEEEECCCCCCCCCCCCH
DLAQYDLNVATRKTLSLKGLL
HHHHHCCCHHHCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA