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The map label for this gene is yfbQ [H]

Identifier: 218548261

GI number: 218548261

Start: 892816

End: 894033

Strand: Reverse

Name: yfbQ [H]

Synonym: EFER_0879

Alternate gene names: 218548261

Gene position: 894033-892816 (Counterclockwise)

Preceding gene: 218548277

Following gene: 218548260

Centisome position: 19.48

GC content: 47.21

Gene sequence:

>1218_bases
ATGTCCCCCATTGAAAAATCCAGCAAACTAGAAAATGTCTGTTACGACATTCGTGGCCCGGTTCTGAAAGAAGCTAAGCG
TCTGGAAGAAGAAGGCAATAAAGTTCTGAAACTTAATATCGGTAACCCGGCCCCTTTTGGTTTTGAGGCGCCTGATGAAA
TCCTGGTTGATGTAATCCGTAATCTGCCAACTGCGCAAGGTTATTGTGATTCAAAAGGGCTGTATTCCGCCCGTAAAGCG
ATCATGCAACATTACCAGGCACGCGGTATGCGCGATGTTACCGTTGAAGATATCTATATTGGGAACGGTGTATCAGAACT
TATTGTTCAGGCGATGCAGGCATTGCTGAACAGTGGGGATGAAATGCTGGTGCCGGCACCTGATTACCCCTTGTGGACTG
CAGCTGTTGCGTTATCCAGCGGAAAAGCGGTGCACTACCTTTGTGATGAGTCATCAGACTGGTTCCCGGATCTTGATGAT
ATCCGTGCCAAAATCACTCCCCGTACGCGCGGTATTGTGATTATCAACCCCAATAACCCAACCGGTGCGGTCTACTCGAA
AGAGTTACTGATGGAAATTGTTGAGATTGCACGCCAGCATAATCTCATAATTTTTGCCGACGAGATTTACGACAAAATTC
TTTACGACGACGCCGAACATCATTCTATTGCACCACTGGCACCCGATTTGTTAACCATCACCTTCAATGGTCTGTCTAAA
ACTTACCGGGTGGCAGGCTTCCGCCAGGGCTGGATGGTCCTTAATGGTCCGAAAAAGCACGCAAAAGGCTATATTGAAGG
GCTGGAAATGCTGGCGTCCATGCGTTTGTGCGCTAACGTACCTGCGCAACATGCCATACAAACCGCGCTTGGTGGTTATC
AAAGCATTAGCGAATTTATTACCCCGGGTGGGCGTTTATATGAACAACGTAATCGGGCCTGGGAATTGATTAATGATATT
CCTGGCGTCTCATGCGTGAAACCACGCGGTGCGTTATATATGTTCCCCAAAATTGATGCCAAACGCTTCAATATTCACGA
TGACCAGAAAATGGTGCTCGATTTCCTGTTACAGGAAAAAGTGTTGCTGGTACAGGGTACGGCATTTAACTGGCCGTGGC
CGGACCACTTCCGTATCGTTACGCTGCCACGAATCGATGATATTGAGATGTCATTGAATAAATTTGCCCGCTTCCTGTCA
GGTTATCATCAGTTGTAA

Upstream 100 bases:

>100_bases
TCCTCTGCAGACTCTTCAAAACTTACTGCAGTGGGAGTACATTGTTCCAGGCTGACTTCCACGGCAGGGAGTGGCGACAA
CAGGAAAAAGGTCAAGATTC

Downstream 100 bases:

>100_bases
ACTCCAAAAATGCTGCCGGAATTTGCATCCGGCGGCATTCTCTGCGCACAATAATCTTCAGGTCTTTATAACCAAAAAGG
TTACTATGAAGCAGAGCCAT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKA
IMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVALSSGKAVHYLCDESSDWFPDLDD
IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSK
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDI
PGVSCVKPRGALYMFPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRIDDIEMSLNKFARFLS
GYHQL

Sequences:

>Translated_405_residues
MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKA
IMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVALSSGKAVHYLCDESSDWFPDLDD
IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSK
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDI
PGVSCVKPRGALYMFPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRIDDIEMSLNKFARFLS
GYHQL
>Mature_404_residues
SPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKAI
MQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVALSSGKAVHYLCDESSDWFPDLDDI
RAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSKT
YRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIP
GVSCVKPRGALYMFPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRIDDIEMSLNKFARFLSG
YHQL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=25.6544502617801, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI19263340, Length=463, Percent_Identity=24.8380129589633, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=26.0869565217391, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4885351, Length=447, Percent_Identity=23.9373601789709, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI95147551, Length=171, Percent_Identity=28.6549707602339, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI169881279, Length=171, Percent_Identity=28.6549707602339, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI56713254, Length=206, Percent_Identity=27.1844660194175, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI56713256, Length=235, Percent_Identity=26.3829787234043, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI169881281, Length=161, Percent_Identity=29.8136645962733, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI149944424, Length=335, Percent_Identity=21.1940298507463, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788627, Length=405, Percent_Identity=98.7654320987654, Blast_Score=836, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=377, Percent_Identity=25.9946949602122, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1786816, Length=226, Percent_Identity=26.1061946902655, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17567663, Length=369, Percent_Identity=29.2682926829268, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71981209, Length=458, Percent_Identity=25.5458515283843, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=205, Percent_Identity=29.7560975609756, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=205, Percent_Identity=29.7560975609756, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=26.6211604095563, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=178, Percent_Identity=29.2134831460674, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=360, Percent_Identity=27.2222222222222, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=357, Percent_Identity=28.0112044817927, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6322401, Length=303, Percent_Identity=24.0924092409241, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI18859735, Length=375, Percent_Identity=26.4, Blast_Score=147, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24641770, Length=470, Percent_Identity=26.3829787234043, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24641760, Length=470, Percent_Identity=26.3829787234043, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24641768, Length=470, Percent_Identity=26.3829787234043, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24641766, Length=470, Percent_Identity=26.3829787234043, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24641764, Length=470, Percent_Identity=26.3829787234043, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI45551451, Length=470, Percent_Identity=26.3829787234043, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI28573069, Length=323, Percent_Identity=24.4582043343653, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24646114, Length=323, Percent_Identity=24.4582043343653, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573067, Length=323, Percent_Identity=24.4582043343653, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573065, Length=323, Percent_Identity=24.4582043343653, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45575; Mature: 45444

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIR
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVALSSGKAVHYLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNP
CEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCH
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFI
HHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
TPGGRLYEQRNRAWELINDIPGVSCVKPRGALYMFPKIDAKRFNIHDDQKMVLDFLLQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCC
VLLVQGTAFNWPWPDHFRIVTLPRIDDIEMSLNKFARFLSGYHQL
EEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIR
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVALSSGKAVHYLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNP
CEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCH
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFI
HHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
TPGGRLYEQRNRAWELINDIPGVSCVKPRGALYMFPKIDAKRFNIHDDQKMVLDFLLQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCC
VLLVQGTAFNWPWPDHFRIVTLPRIDDIEMSLNKFARFLSGYHQL
EEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]