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The map label for this gene is murQ [H]

Identifier: 218548132

GI number: 218548132

Start: 762216

End: 763112

Strand: Reverse

Name: murQ [H]

Synonym: EFER_0744

Alternate gene names: 218548132

Gene position: 763112-762216 (Counterclockwise)

Preceding gene: 218548140

Following gene: 218548131

Centisome position: 16.63

GC content: 52.73

Gene sequence:

>897_bases
ATGCAACTTGAAAAGATGATTACCGAAGGCTCGAACGCCGCTTCGGCTGAAATTGACCGCGTATCAACGCTGGAAATGTG
TCGGATTATCAACGATGAAGATAAAACCGTACCACTCGCCGTTGAGCGTGTACTGCCGGATATCGCCGCAGCGATCGATG
TTATCCACGCCCAGGTAAGCGGCGGCGGTCGACTGATTTACATCGGTGCGGGTACTTCCGGTCGTCTGGGTATTCTTGAT
GCCAGCGAATGTCCGCCGACCTACGGCGTGAAACCGGGCCTGGTGGTTGGTTTGATTGCTGGCGGTGAATATGCCATTCA
GCACGCGGTGGAAGGCGCAGAAGATAGCCGGGAAGGTGGCGTTAACGATCTAAAAAATATCGGCTTAACCGCACAGGATG
TGGTGGTTGGTATTGCTGCCAGTGGTCGCACACCGTATGTGATTGCCGGGCTGGAATACGCACGCCAACTCGGTTGCCGC
ACAGTGGGCATTTCCTGTAATCCAGGGAGTGCTGTTTCCACCACCGCTGAGTTTGCTATTACTCCGGTGGTTGGTGCCGA
AGTGGTTACCGGTTCTTCGCGAATGAAAGCAGGCACAGCGCAGAAACTGGTGCTCAATATGCTTTCTACCGGGCTGATGA
TTAAATCCGGCAAAGTGTTCGGCAACCTGATGGTCGATGTGGTCGCCACCAACGAAAAATTGCATGTGCGCCAGGTCAAT
ATCGTTAAAAACGCCACCGGATGTAACGCCGAAAAAGCGGAAGCGGCGTTAATTGCTTGCGAGCGCAACTGCAAAACGGC
CATTGTGATGGTGCTGAAAAATCTCGATGCCGCAGAAGCAAAAAAACGCCTGGATCAACACGGCGGCTTTATTCGTCAGG
TTTTAGACAAGGAATAA

Upstream 100 bases:

>100_bases
TGCGAGTGTAGACTCAATGATTCCTTTAAGTCTGTCAATTCGGGATATATGATTCCATCCATCTGCAATTATTTGATCGT
AAATAGTAAGGTCACCACCG

Downstream 100 bases:

>100_bases
CCCATGGCCAAAGAGATCAGCAGTGAACTTCTGAACACCATCCTTACCCGTGTCGGCGGACCGGGGAATATCGCCAGTTG
TGGTAACTGTATGACGCGCC

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVSGGGRLIYIGAGTSGRLGILD
ASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
TVGISCNPGSAVSTTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVN
IVKNATGCNAEKAEAALIACERNCKTAIVMVLKNLDAAEAKKRLDQHGGFIRQVLDKE

Sequences:

>Translated_298_residues
MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVSGGGRLIYIGAGTSGRLGILD
ASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
TVGISCNPGSAVSTTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVN
IVKNATGCNAEKAEAALIACERNCKTAIVMVLKNLDAAEAKKRLDQHGGFIRQVLDKE
>Mature_298_residues
MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVSGGGRLIYIGAGTSGRLGILD
ASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
TVGISCNPGSAVSTTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVN
IVKNATGCNAEKAEAALIACERNCKTAIVMVLKNLDAAEAKKRLDQHGGFIRQVLDKE

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=298, Percent_Identity=97.6510067114094, Blast_Score=590, Evalue=1e-170,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31112; Mature: 31112

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVS
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEC
GGGRLIYIGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGG
CCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCCCC
VNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCRTVGISCNPGSAVSTTAEFAI
CHHHHHCCCCHHHEEEEEECCCCCCEEEECHHHHHHCCCEEEEEECCCCCCCCCCHHEEE
TPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVN
ECCCCCEEEECCCHHCCCHHHHHHHHHHHCCEEEECCCEEEEEEEEEEECCCEEEEEEEE
IVKNATGCNAEKAEAALIACERNCKTAIVMVLKNLDAAEAKKRLDQHGGFIRQVLDKE
EEECCCCCCCHHHHEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVS
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEC
GGGRLIYIGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGG
CCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCCCC
VNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCRTVGISCNPGSAVSTTAEFAI
CHHHHHCCCCHHHEEEEEECCCCCCEEEECHHHHHHCCCEEEEEECCCCCCCCCCHHEEE
TPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVN
ECCCCCEEEECCCHHCCCHHHHHHHHHHHCCEEEECCCEEEEEEEEEEECCCEEEEEEEE
IVKNATGCNAEKAEAALIACERNCKTAIVMVLKNLDAAEAKKRLDQHGGFIRQVLDKE
EEECCCCCCCHHHHEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA