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The map label for this gene is yfhR [H]

Identifier: 218548029

GI number: 218548029

Start: 637669

End: 638520

Strand: Reverse

Name: yfhR [H]

Synonym: EFER_0638

Alternate gene names: 218548029

Gene position: 638520-637669 (Counterclockwise)

Preceding gene: 218548030

Following gene: 218548028

Centisome position: 13.92

GC content: 46.6

Gene sequence:

>852_bases
ATGATTGTTGCGGTTAATAAGCGCGTTCTAAAAATTGTCTTTATTTTGTTCGTCATTCTGTTCTGCGTTTATTTAATACC
GCGTATCGCTATCAATTTTTTCTATTACCCGGACGATAAAATTTATGGCCCCGATCCCTGGTCTGCCGAATCAGTAGAAT
TCACTGCCAAAGACGGCACACGCCTGCACGGCTGGTTTATTCCTTCTGCGACTGGCCCCGCCGAAAACGCCATTGCGACT
GTCATTCACGCTCACGGCAATGCAGGCAATATGTCCGCACACTGGCCATTGGTCAGTTGGTTACCGGAACGGAATTTCAA
TGTCTTTATGTTTGATTATCGTGGATTCGGTAAATCAAAGGGAAGACCTTCTCAGGCAGGGTTATTAGATGATACGCAAA
GTGCGATTAATGTTGTGCGCCACCGCAGTGATGTTAACCCGCAACGTCTGGTCTTGTTTGGCCAAAGTATTGGTGGCGCG
AATATGGTTAGTGCTCTTGGGAATGGTGATCGCGAAGGTATTCGCGCGGTAATTCTCGACTCAACCTTTGCTTCTTATTC
CTCAATCGCTAACCAGATGATCCCCGGTAGCGGTTTCTTTATGGACGACAGTTATAATGCGGAACGCTTCATCGCTGAAG
TCAGCCCCATTCCTGTACTGATCATTCATGGTAAAGCTGATCGCGTCATTCCCTGGGAGCAAAGTGAAAGGCTTTATGAT
CTCACCCGCGAACCGAAACAAAAAATTATCCTTCCTGATGGTGAACATATCGACGCCTTTTCAGAACGCCATGGCGGGGT
ATATCGCGACCAGATGGTGAATTTTATCCTCAATGCATTAAACACCCGATGA

Upstream 100 bases:

>100_bases
ACTCTTCAGGCGCTTTTCTGAAACTGCACACCTTCACTTTACATTCCTTCACTGCTCTCACACCATCTTTCCGTTTTTAG
TCTATTTCAGGGAAAGAGAG

Downstream 100 bases:

>100_bases
CATCGCAACTCTCTCTGAGGTGAAAGAAGACAGCACAAAATCACCTTAAGGTGCTCGCTTCGTCTTAACAAAGCCAACTC
TCCAGTTAAAAATTCTGTGA

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MIVAVNKRVLKIVFILFVILFCVYLIPRIAINFFYYPDDKIYGPDPWSAESVEFTAKDGTRLHGWFIPSATGPAENAIAT
VIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSKGRPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
NMVSALGNGDREGIRAVILDSTFASYSSIANQMIPGSGFFMDDSYNAERFIAEVSPIPVLIIHGKADRVIPWEQSERLYD
LTREPKQKIILPDGEHIDAFSERHGGVYRDQMVNFILNALNTR

Sequences:

>Translated_283_residues
MIVAVNKRVLKIVFILFVILFCVYLIPRIAINFFYYPDDKIYGPDPWSAESVEFTAKDGTRLHGWFIPSATGPAENAIAT
VIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSKGRPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
NMVSALGNGDREGIRAVILDSTFASYSSIANQMIPGSGFFMDDSYNAERFIAEVSPIPVLIIHGKADRVIPWEQSERLYD
LTREPKQKIILPDGEHIDAFSERHGGVYRDQMVNFILNALNTR
>Mature_283_residues
MIVAVNKRVLKIVFILFVILFCVYLIPRIAINFFYYPDDKIYGPDPWSAESVEFTAKDGTRLHGWFIPSATGPAENAIAT
VIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSKGRPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
NMVSALGNGDREGIRAVILDSTFASYSSIANQMIPGSGFFMDDSYNAERFIAEVSPIPVLIIHGKADRVIPWEQSERLYD
LTREPKQKIILPDGEHIDAFSERHGGVYRDQMVNFILNALNTR

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine esterase family [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=245, Percent_Identity=30.6122448979592, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI71051602, Length=229, Percent_Identity=29.2576419213974, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI71051600, Length=229, Percent_Identity=29.2576419213974, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI194306564, Length=195, Percent_Identity=33.8461538461538, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI151301175, Length=187, Percent_Identity=32.620320855615, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI194306562, Length=213, Percent_Identity=30.9859154929577, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI32451492, Length=198, Percent_Identity=28.2828282828283, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI32528310, Length=198, Percent_Identity=28.2828282828283, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI24308097, Length=192, Percent_Identity=27.6041666666667, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI109689718, Length=193, Percent_Identity=28.4974093264249, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI226510965, Length=283, Percent_Identity=81.9787985865724, Blast_Score=501, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI71988362, Length=206, Percent_Identity=28.6407766990291, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324009, Length=217, Percent_Identity=29.9539170506912, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17137566, Length=273, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281362521, Length=206, Percent_Identity=29.6116504854369, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281362519, Length=206, Percent_Identity=29.6116504854369, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28571878, Length=206, Percent_Identity=29.6116504854369, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001375 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 31676; Mature: 31676

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVAVNKRVLKIVFILFVILFCVYLIPRIAINFFYYPDDKIYGPDPWSAESVEFTAKDGT
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEECCCC
RLHGWFIPSATGPAENAIATVIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSK
EEEEEECCCCCCCCHHHEEEEEEECCCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCCCC
GRPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGANMVSALGNGDREGIRAVILD
CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCEEEEEEE
STFASYSSIANQMIPGSGFFMDDSYNAERFIAEVSPIPVLIIHGKADRVIPWEQSERLYD
CHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHH
LTREPKQKIILPDGEHIDAFSERHGGVYRDQMVNFILNALNTR
HHCCCCCEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIVAVNKRVLKIVFILFVILFCVYLIPRIAINFFYYPDDKIYGPDPWSAESVEFTAKDGT
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEECCCC
RLHGWFIPSATGPAENAIATVIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSK
EEEEEECCCCCCCCHHHEEEEEEECCCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCCCC
GRPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGANMVSALGNGDREGIRAVILD
CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCEEEEEEE
STFASYSSIANQMIPGSGFFMDDSYNAERFIAEVSPIPVLIIHGKADRVIPWEQSERLYD
CHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHH
LTREPKQKIILPDGEHIDAFSERHGGVYRDQMVNFILNALNTR
HHCCCCCEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]