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The map label for this gene is intD [H]

Identifier: 218547967

GI number: 218547967

Start: 590641

End: 591804

Strand: Reverse

Name: intD [H]

Synonym: EFER_0572

Alternate gene names: 218547967

Gene position: 591804-590641 (Counterclockwise)

Preceding gene: 218547968

Following gene: 218547966

Centisome position: 12.9

GC content: 49.66

Gene sequence:

>1164_bases
ATGTCACTCTTCCGCAGAGGTGAAATATGGTACGCCTCGTACTCGCTCCCGGGCGGGAAGCGAATTAAGGAATCTCTTGG
CACAAAGGACAAGCGGCAAGCGCAGGAGCTGCACGACAAACGAAAAGCTGAGCTCTGGCGAGTAGACAGGCTTGGTGATT
TTCCAGATGTGACGTTTGAAGAAGCATGCTTGCGCTGGATTGAAGAGAAATCAGATAAGAAATCGCTCGATACAGATAAA
GGCCGGATGGGATTCTGGCTTGAGCATTTTGAAGGTGTGCGGCTAAAGGATATTACTGAGGCAAGGATTTACTCAGCCGT
CAGCAGGATGCATAACCGTAATCACCTTGAGATATGGAAAGCAAAGGCAGAGGCGGCAAGGAAGAAAGGAAAACCTGTGC
CTGAATATGTCGCTAAACCAGTCACCACTGCCACCAAGGCAAAGCATCTTGCACTGATGAAAGCCATTCTGAGAGCAGCA
GAACGTGACTGGAAATGGCTGGAGAAAGCACCGGTCATCAAGATACCGACAGTACGCAACAAGCGTGTGCGGTGGCTGGA
AAAGGAGGAAGCAAAAAGGCTGATTGATGAATGCCCGGAGCCATTAAAGTCTGTCGTCAAGTTTGCACTGGCGACAGGTT
TACGGCGTTCGAACATTATCAATTTGGAGTGGCAACAGATAGACATGCAGCGCCGTGTTGCGTGGATCAACCCGGAAGAC
AGTAAATCAAACAGAGCTATTGGCGTAGCGCTGAATGATACTGCATGTAAGGTTCTGCGAGACCAGATAGGCAACCATCA
TAAATTTGTGTTCGTACACACAAAGCCAGCAAGACGGCCTGATGGCTCTCTCACTCCTGCAGTCAGAAAGATGCGAGTCG
ATGACGGCAGAGCCTGGAAGGCAGCGTGCAGACGAGCAGGTATTGAGGATTTCCGTTTTCATGACCTGAGACACACATGG
GCGAGCTGGCTTATTCAGGCTGGCGTGCCGTTATCTGTGCTTCAGGAAATGGGAGGATGGGAATCAATCGAAATGGTACG
CAGGTATGCTCACCTGGCACCTAATCACCTGACCGAGCACGCAAAGCAAATTGACGCTATTTTTAACGATGATGTCCCAA
ATTTGTCCCACAAAGGAAAAGCAGAAGCGGGAGGAAGCATTTAA

Upstream 100 bases:

>100_bases
CCCCTTACCTCACAACACGACAAGCCTGCATTGCGGCGCTTCAGTCTCCGCTGCATACTGTCCAGGTGAGCGCGGGTGAT
GGCATAACAGAGGAAAGAAA

Downstream 100 bases:

>100_bases
GTGATTGATTCTAAATGGCGCCCCCTGCAGGATTCGAACCTGCGACCGACGGCTTAGAAGGCCGTTGCTCTATCCAGCTG
AGCTAAGGGAGCATAGAAAG

Product: integrase; DLP12 prophage

Products: NA

Alternate protein names: Prophage QSR' integrase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSLFRRGEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAELWRVDRLGDFPDVTFEEACLRWIEEKSDKKSLDTDK
GRMGFWLEHFEGVRLKDITEARIYSAVSRMHNRNHLEIWKAKAEAARKKGKPVPEYVAKPVTTATKAKHLALMKAILRAA
ERDWKWLEKAPVIKIPTVRNKRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRRSNIINLEWQQIDMQRRVAWINPED
SKSNRAIGVALNDTACKVLRDQIGNHHKFVFVHTKPARRPDGSLTPAVRKMRVDDGRAWKAACRRAGIEDFRFHDLRHTW
ASWLIQAGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHAKQIDAIFNDDVPNLSHKGKAEAGGSI

Sequences:

>Translated_387_residues
MSLFRRGEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAELWRVDRLGDFPDVTFEEACLRWIEEKSDKKSLDTDK
GRMGFWLEHFEGVRLKDITEARIYSAVSRMHNRNHLEIWKAKAEAARKKGKPVPEYVAKPVTTATKAKHLALMKAILRAA
ERDWKWLEKAPVIKIPTVRNKRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRRSNIINLEWQQIDMQRRVAWINPED
SKSNRAIGVALNDTACKVLRDQIGNHHKFVFVHTKPARRPDGSLTPAVRKMRVDDGRAWKAACRRAGIEDFRFHDLRHTW
ASWLIQAGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHAKQIDAIFNDDVPNLSHKGKAEAGGSI
>Mature_386_residues
SLFRRGEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAELWRVDRLGDFPDVTFEEACLRWIEEKSDKKSLDTDKG
RMGFWLEHFEGVRLKDITEARIYSAVSRMHNRNHLEIWKAKAEAARKKGKPVPEYVAKPVTTATKAKHLALMKAILRAAE
RDWKWLEKAPVIKIPTVRNKRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRRSNIINLEWQQIDMQRRVAWINPEDS
KSNRAIGVALNDTACKVLRDQIGNHHKFVFVHTKPARRPDGSLTPAVRKMRVDDGRAWKAACRRAGIEDFRFHDLRHTWA
SWLIQAGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHAKQIDAIFNDDVPNLSHKGKAEAGGSI

Specific function: Integrase from the cryptic lambdoic prophage DLP12. Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1786748, Length=377, Percent_Identity=85.4111405835544, Blast_Score=677, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44662; Mature: 44531

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFRRGEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAELWRVDRLGDFPDVTFE
CCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
EACLRWIEEKSDKKSLDTDKGRMGFWLEHFEGVRLKDITEARIYSAVSRMHNRNHLEIWK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
AKAEAARKKGKPVPEYVAKPVTTATKAKHLALMKAILRAAERDWKWLEKAPVIKIPTVRN
HHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
KRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRRSNIINLEWQQIDMQRRVAWINPED
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHCCEEECHHHHHHHHHHEEECCCCC
SKSNRAIGVALNDTACKVLRDQIGNHHKFVFVHTKPARRPDGSLTPAVRKMRVDDGRAWK
CCCCCEEEEEECHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCCHHHH
AACRRAGIEDFRFHDLRHTWASWLIQAGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEH
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCHHHHHHH
AKQIDAIFNDDVPNLSHKGKAEAGGSI
HHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLFRRGEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAELWRVDRLGDFPDVTFE
CCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
EACLRWIEEKSDKKSLDTDKGRMGFWLEHFEGVRLKDITEARIYSAVSRMHNRNHLEIWK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
AKAEAARKKGKPVPEYVAKPVTTATKAKHLALMKAILRAAERDWKWLEKAPVIKIPTVRN
HHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
KRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRRSNIINLEWQQIDMQRRVAWINPED
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHCCEEECHHHHHHHHHHEEECCCCC
SKSNRAIGVALNDTACKVLRDQIGNHHKFVFVHTKPARRPDGSLTPAVRKMRVDDGRAWK
CCCCCEEEEEECHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCCHHHH
AACRRAGIEDFRFHDLRHTWASWLIQAGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEH
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCHHHHHHH
AKQIDAIFNDDVPNLSHKGKAEAGGSI
HHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2553674; 2183007; 9278503 [H]