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The map label for this gene is ybbK [H]

Identifier: 218547944

GI number: 218547944

Start: 570355

End: 571272

Strand: Reverse

Name: ybbK [H]

Synonym: EFER_0547

Alternate gene names: 218547944

Gene position: 571272-570355 (Counterclockwise)

Preceding gene: 218547947

Following gene: 218547943

Centisome position: 12.45

GC content: 50.65

Gene sequence:

>918_bases
ATGTTTATCTTTATTCCCATTCTCATTTTTGTCGCGCTGGTCATTGTTGGCGCGGGTGTCAAAATCGTACCGCAGGGATA
TCAGTGGACAGTAGAACGTTTTGGTCGCTATACCAAAACGTTACAGCCGGGGCTCAGTCTGGTGGTGCCGTTTATGGATC
GCATTGGTCGTAAGATCAATATGATGGAGCAAGTGCTCGATATCCCTTCTCAGGAAGTTATCTCGAAAGATAACGCCAAC
GTTACTATCGACGCCGTGTGCTTTATTCAGGTGATTGACGCGCCGCGCGCGGCTTATGAGGTCAGCAATCTGGAGCTGGC
GATCATCAACCTGACCATGACTAACATCCGTACCGTGCTGGGTTCAATGGAACTCGATGAAATGCTCTCCCAGCGCGACA
GCATCAACTCACGTCTGCTACGTATTGTCGATGAGGCCACCAACCCGTGGGGGATTAAAGTCACCCGTATTGAAATTCGC
GACGTACGCCCGCCCGCAGAGCTTATCTCTTCAATGAACGCGCAGATGAAAGCGGAACGTACTAAACGCGCTTACATCCT
TGAAGCTGAAGGGATCCGTCAGGCGGAAATTCTCAAAGCGGAAGGTGAGAAACAGTCACAAATCCTGAAAGCGGAAGGCG
AACGTCAGTCGGCATTTTTGCAAGCTGAAGCGCGTGAACGTTCCGCTGAAGCAGAAGCCCGTGCTACCCAAATGGTGTCG
GAAGCCATCGCCTCTGGTGATATTCAGGCAGTGAACTACTTCGTAGCACAGAAATATACCGAAGCGTTGCAGCAGATCGG
TTCTTCCAGTAACAGCAAAGTAGTAATGATGCCATTAGAGGCCAGCAGCCTGATGGGGTCGATTGCCGGGATTGCTGAAC
TGGTGAAAGACAGCGCGAACGAGCGAAATAAATCATGA

Upstream 100 bases:

>100_bases
GAAGGATTGTGGGGGAACTATCATTTATTAATCAGGTATAATTTAGCTGAGCAGACAACAATCGCTTTTATTATGGACGG
TACAACAGGAGGTTTTTTCG

Downstream 100 bases:

>100_bases
TCGAGATGATAGCTATCCATCCGCATATTTTTTGGCTAAGTCTCGGCGGTTTGTTGCTGGCTGCCGAGATGCTGGGCGGC
AATGGTTATCTGTTGTGGAG

Product: protease, membrane anchored

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MFIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNAN
VTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
EAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSANERNKS

Sequences:

>Translated_305_residues
MFIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNAN
VTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
EAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSANERNKS
>Mature_305_residues
MFIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNAN
VTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
EAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSANERNKS

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=264, Percent_Identity=34.8484848484849, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI221316744, Length=193, Percent_Identity=34.7150259067358, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI21686995, Length=193, Percent_Identity=34.7150259067358, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38016911, Length=192, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI7657615, Length=138, Percent_Identity=34.7826086956522, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1786697, Length=304, Percent_Identity=98.3552631578947, Blast_Score=604, Evalue=1e-174,
Organism=Escherichia coli, GI1790616, Length=211, Percent_Identity=23.2227488151659, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI32564147, Length=299, Percent_Identity=35.1170568561873, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17569493, Length=222, Percent_Identity=33.7837837837838, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI193209764, Length=217, Percent_Identity=35.4838709677419, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71989948, Length=155, Percent_Identity=36.7741935483871, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71989955, Length=155, Percent_Identity=36.7741935483871, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71987612, Length=192, Percent_Identity=34.8958333333333, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25153583, Length=192, Percent_Identity=34.8958333333333, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71987621, Length=218, Percent_Identity=33.4862385321101, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17569499, Length=174, Percent_Identity=35.632183908046, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17569497, Length=193, Percent_Identity=29.5336787564767, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17570459, Length=203, Percent_Identity=35.9605911330049, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32566490, Length=188, Percent_Identity=33.5106382978723, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193210507, Length=195, Percent_Identity=34.3589743589744, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17570161, Length=195, Percent_Identity=34.3589743589744, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71989963, Length=120, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45550506, Length=275, Percent_Identity=36, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI45556022, Length=193, Percent_Identity=34.7150259067358, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24657857, Length=199, Percent_Identity=35.1758793969849, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI62484448, Length=199, Percent_Identity=35.1758793969849, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281365664, Length=199, Percent_Identity=35.1758793969849, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI62484274, Length=199, Percent_Identity=35.1758793969849, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18860517, Length=199, Percent_Identity=31.1557788944724, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21356845, Length=191, Percent_Identity=26.1780104712042, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281361633, Length=194, Percent_Identity=26.8041237113402, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281361631, Length=194, Percent_Identity=26.8041237113402, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573263, Length=198, Percent_Identity=26.2626262626263, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 33782; Mature: 33782

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01270 BAND_7

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKIN
CEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHH
MMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVL
HHHHHHCCCCHHHHCCCCCCEEEEHEEEEHHHCCCHHHEEECCCEEEEEEEEHHHHHHHH
GSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIRDVRPPAELISSMNAQMKAER
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHH
TKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
HHHEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSAN
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHC
ERNKS
CCCCC
>Mature Secondary Structure
MFIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKIN
CEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHH
MMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVL
HHHHHHCCCCHHHHCCCCCCEEEEHEEEEHHHCCCHHHEEECCCEEEEEEEEHHHHHHHH
GSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIRDVRPPAELISSMNAQMKAER
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHH
TKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
HHHEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSAN
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHC
ERNKS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]