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The map label for this gene is fbp [H]

Identifier: 218532985

GI number: 218532985

Start: 5476525

End: 5476947

Strand: Reverse

Name: fbp [H]

Synonym: Mchl_5109

Alternate gene names: 218532985

Gene position: 5476947-5476525 (Counterclockwise)

Preceding gene: 218532986

Following gene: 218532981

Centisome position: 94.79

GC content: 70.21

Gene sequence:

>423_bases
ATGCGCTCGATCCTTCCCCTAGCCGGAGCCATCGCCCTCGCCATGACCAGTGCCGCTTCCGCCGCCCAGCCCGTCACGCT
GCCCTCGGGCCTCAGCTACACCGATGAAGTGGTCGGCACCGGCCCCGAGCCGAAGTCCGGCCAGCAGGTCACCGTCCACT
ATACCGGCTGGCTCGACGAGGGCGGCGGCAAGCGGGGCAAGAAGTTCGATTCGTCGCGTGATCGCGGCCAGCCCTTCTCG
TTCACCATCGGCGCGGGCCAAGTGATCCGCGGCTGGGACGAGGGCGTTGCCACGATGAAGGCCGGCGGCCGCCGCATCCT
GACGATCCCGCCGGATCTCGGCTACGGCGCCCGCGGTGCCGGCGGCGTGATCCCGCCGAACGCCACGCTGATCTTCGACG
TCGAGCTGATCGGCTCGCGCTGA

Upstream 100 bases:

>100_bases
ATGGAGCGTGGGGCCATCCGGGCCCGTTATTAGCCTTGTGGCCGGGCGCGTGCTAACCCGCGCGCCCCGTCGTCAGCGAC
GACGCGCCGAGACGAGATTC

Downstream 100 bases:

>100_bases
TCCCGAACTTCTCCGGCGCCCCTGTGGGCGCCGGATCCGGTGGGCGAAAGCCTCAGATGAGCTTGTGCTCGCGTGCCAGC
GCCAGCAGATCGCGCTGCGG

Product: peptidylprolyl isomerase FKBP-type

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MRSILPLAGAIALAMTSAASAAQPVTLPSGLSYTDEVVGTGPEPKSGQQVTVHYTGWLDEGGGKRGKKFDSSRDRGQPFS
FTIGAGQVIRGWDEGVATMKAGGRRILTIPPDLGYGARGAGGVIPPNATLIFDVELIGSR

Sequences:

>Translated_140_residues
MRSILPLAGAIALAMTSAASAAQPVTLPSGLSYTDEVVGTGPEPKSGQQVTVHYTGWLDEGGGKRGKKFDSSRDRGQPFS
FTIGAGQVIRGWDEGVATMKAGGRRILTIPPDLGYGARGAGGVIPPNATLIFDVELIGSR
>Mature_140_residues
MRSILPLAGAIALAMTSAASAAQPVTLPSGLSYTDEVVGTGPEPKSGQQVTVHYTGWLDEGGGKRGKKFDSSRDRGQPFS
FTIGAGQVIRGWDEGVATMKAGGRRILTIPPDLGYGARGAGGVIPPNATLIFDVELIGSR

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=94, Percent_Identity=60.6382978723404, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI4503725, Length=94, Percent_Identity=60.6382978723404, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI4758380, Length=95, Percent_Identity=60, Blast_Score=115, Evalue=1e-26,
Organism=Homo sapiens, GI4503729, Length=137, Percent_Identity=45.985401459854, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI224809331, Length=101, Percent_Identity=51.4851485148515, Blast_Score=97, Evalue=5e-21,
Organism=Homo sapiens, GI224809329, Length=101, Percent_Identity=51.4851485148515, Blast_Score=96, Evalue=8e-21,
Organism=Homo sapiens, GI224809327, Length=101, Percent_Identity=51.4851485148515, Blast_Score=96, Evalue=8e-21,
Organism=Homo sapiens, GI4758384, Length=101, Percent_Identity=51.4851485148515, Blast_Score=96, Evalue=8e-21,
Organism=Homo sapiens, GI206725530, Length=93, Percent_Identity=49.4623655913978, Blast_Score=93, Evalue=9e-20,
Organism=Homo sapiens, GI17149844, Length=93, Percent_Identity=49.4623655913978, Blast_Score=93, Evalue=9e-20,
Organism=Homo sapiens, GI17149842, Length=93, Percent_Identity=49.4623655913978, Blast_Score=93, Evalue=9e-20,
Organism=Homo sapiens, GI192448443, Length=95, Percent_Identity=45.2631578947368, Blast_Score=82, Evalue=1e-16,
Organism=Homo sapiens, GI8923659, Length=98, Percent_Identity=43.8775510204082, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI4503727, Length=117, Percent_Identity=39.3162393162393, Blast_Score=79, Evalue=9e-16,
Organism=Homo sapiens, GI33469985, Length=93, Percent_Identity=45.1612903225806, Blast_Score=79, Evalue=9e-16,
Organism=Homo sapiens, GI206725547, Length=94, Percent_Identity=44.6808510638298, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI31317231, Length=95, Percent_Identity=45.2631578947368, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI150010552, Length=103, Percent_Identity=35.9223300970874, Blast_Score=73, Evalue=9e-14,
Organism=Homo sapiens, GI17149839, Length=56, Percent_Identity=55.3571428571429, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1789745, Length=115, Percent_Identity=45.2173913043478, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI87082390, Length=109, Percent_Identity=44.954128440367, Blast_Score=81, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71993519, Length=96, Percent_Identity=58.3333333333333, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17540882, Length=137, Percent_Identity=43.0656934306569, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17561782, Length=94, Percent_Identity=54.2553191489362, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71993555, Length=73, Percent_Identity=49.3150684931507, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561778, Length=106, Percent_Identity=37.7358490566038, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324194, Length=94, Percent_Identity=55.3191489361702, Blast_Score=105, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320727, Length=94, Percent_Identity=54.2553191489362, Blast_Score=101, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323482, Length=126, Percent_Identity=42.0634920634921, Blast_Score=86, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323566, Length=115, Percent_Identity=41.7391304347826, Blast_Score=83, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281363946, Length=142, Percent_Identity=48.5915492957746, Blast_Score=129, Evalue=8e-31,
Organism=Drosophila melanogaster, GI17352457, Length=142, Percent_Identity=48.5915492957746, Blast_Score=129, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24655568, Length=94, Percent_Identity=64.8936170212766, Blast_Score=125, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24647110, Length=117, Percent_Identity=48.7179487179487, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24583150, Length=101, Percent_Identity=51.4851485148515, Blast_Score=102, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21356629, Length=134, Percent_Identity=47.7611940298507, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 14455; Mature: 14455

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSILPLAGAIALAMTSAASAAQPVTLPSGLSYTDEVVGTGPEPKSGQQVTVHYTGWLDE
CCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHCCCCCCCCCCCEEEEEEECEEEC
GGGKRGKKFDSSRDRGQPFSFTIGAGQVIRGWDEGVATMKAGGRRILTIPPDLGYGARGA
CCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCEEECCCCCCEEEECCCCCCCCCCCC
GGVIPPNATLIFDVELIGSR
CCCCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MRSILPLAGAIALAMTSAASAAQPVTLPSGLSYTDEVVGTGPEPKSGQQVTVHYTGWLDE
CCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHCCCCCCCCCCCEEEEEEECEEEC
GGGKRGKKFDSSRDRGQPFSFTIGAGQVIRGWDEGVATMKAGGRRILTIPPDLGYGARGA
CCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCEEECCCCCCEEEECCCCCCCCCCCC
GGVIPPNATLIFDVELIGSR
CCCCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]