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The map label for this gene is yajO [H]

Identifier: 218532969

GI number: 218532969

Start: 5455801

End: 5456781

Strand: Reverse

Name: yajO [H]

Synonym: Mchl_5093

Alternate gene names: 218532969

Gene position: 5456781-5455801 (Counterclockwise)

Preceding gene: 218532970

Following gene: 218532968

Centisome position: 94.44

GC content: 67.18

Gene sequence:

>981_bases
ATGCAGACAAAAAAACTCGGCCGCACCGGCCTCGACATCTCGCCCCTCTGCCTCGGCTGCATGACCTACGGCGTGCCGGA
GCGGGGACCGCATCCGTGGACCCTGCGGGAGGAGGAGAGCCGGCCGCTGATCAAGCGGGCGCTCGATCTCGGGATCAACT
TCTTCGATACCGCGAACTACTATTCGGACGGCACCTCCGAGGAGATCGTCGGCCGCGCTCTCAAGGACTACGCCGACCGC
GACAGCATCGTACTGGCCACCAAGGTCTACTACCCGCAGAAGAACCAGCCCAATGCCGGCGGCCTCTCGCGCAAGGCGAT
CTTTTCCGCGATCGACGCTTCACTGAAGCGGCTCGGCACCGATTACGTCGATCTCTACCAAATCCATCGCTGGGACTACG
CCACGCCGATTGAGGTGACGCTGGAAGCGCTGCACGACGTCGTGAAGGCGGGCAAGGCCCGCTACATCGGGGCCTCGTCG
ATGTTCGCGTGGCAGTTCGCCAAGGCGCTCTACACTTCTGACCTGAACGGCTGGACGCGGTTCGCGACGATGCAGAACCA
CCTCAACCTGCTGCACCGCGAGGAGGAACGGGAGATGATCCCGCTCTGCGCCGACCAGGGCATCCCGCTCCTGCCCTGGA
GCCCGCTCGCCCGTGGCCGGCTCACCCGCGACTTCGACGCGGGCAGCGCCCGGCAGGAAAGCGATCTCGTGGGCAAGAAC
CTCTACGACGCCACGGTCGAGGCCGACCGGCAGGTGGTCGAGGCGGTGGCCGACGTCGCGCGCGACCGCGGCGTGCCTCG
GGCGCAGGTGGCGCTCGCCTGGGTGATCCAGAAGCGGGGCGTGGCCGCCCCGATCATCGGCGCCTCGAAGCCGGGACACC
TCGACGACGCGGCGGCGGCCCTCGACCTCGAATTGATGCCGGACGAGATCGCCCGGCTCGAAGCCCCTTACGTTCCGCAC
GCCGTGGTCGGGTTCCAATGA

Upstream 100 bases:

>100_bases
AAACTCGCCTTCATGATGCGCCGCGAGGGGCGGGGCGGGTGACGGACCGCTGCGGCGCCCCAGTTAAGCGGCTCCGACCC
GCCTCCGCGTGACCGATCCC

Downstream 100 bases:

>100_bases
TGCGCCGCCTGCTCCTCCTGCGCCACGCCAAATCCGCCTACCCGCAGGGCGTGGCCGATATCGACCGCCCGCTCAATGGG
CGCGGGCGGGAGGCCGCACC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MQTKKLGRTGLDISPLCLGCMTYGVPERGPHPWTLREEESRPLIKRALDLGINFFDTANYYSDGTSEEIVGRALKDYADR
DSIVLATKVYYPQKNQPNAGGLSRKAIFSAIDASLKRLGTDYVDLYQIHRWDYATPIEVTLEALHDVVKAGKARYIGASS
MFAWQFAKALYTSDLNGWTRFATMQNHLNLLHREEEREMIPLCADQGIPLLPWSPLARGRLTRDFDAGSARQESDLVGKN
LYDATVEADRQVVEAVADVARDRGVPRAQVALAWVIQKRGVAAPIIGASKPGHLDDAAAALDLELMPDEIARLEAPYVPH
AVVGFQ

Sequences:

>Translated_326_residues
MQTKKLGRTGLDISPLCLGCMTYGVPERGPHPWTLREEESRPLIKRALDLGINFFDTANYYSDGTSEEIVGRALKDYADR
DSIVLATKVYYPQKNQPNAGGLSRKAIFSAIDASLKRLGTDYVDLYQIHRWDYATPIEVTLEALHDVVKAGKARYIGASS
MFAWQFAKALYTSDLNGWTRFATMQNHLNLLHREEEREMIPLCADQGIPLLPWSPLARGRLTRDFDAGSARQESDLVGKN
LYDATVEADRQVVEAVADVARDRGVPRAQVALAWVIQKRGVAAPIIGASKPGHLDDAAAALDLELMPDEIARLEAPYVPH
AVVGFQ
>Mature_326_residues
MQTKKLGRTGLDISPLCLGCMTYGVPERGPHPWTLREEESRPLIKRALDLGINFFDTANYYSDGTSEEIVGRALKDYADR
DSIVLATKVYYPQKNQPNAGGLSRKAIFSAIDASLKRLGTDYVDLYQIHRWDYATPIEVTLEALHDVVKAGKARYIGASS
MFAWQFAKALYTSDLNGWTRFATMQNHLNLLHREEEREMIPLCADQGIPLLPWSPLARGRLTRDFDAGSARQESDLVGKN
LYDATVEADRQVVEAVADVARDRGVPRAQVALAWVIQKRGVAAPIIGASKPGHLDDAAAALDLELMPDEIARLEAPYVPH
AVVGFQ

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=312, Percent_Identity=30.7692307692308, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=30.7443365695793, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI27436964, Length=314, Percent_Identity=29.6178343949045, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI27436962, Length=314, Percent_Identity=29.6178343949045, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI27436966, Length=314, Percent_Identity=29.6178343949045, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI27436971, Length=328, Percent_Identity=28.0487804878049, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI223718702, Length=187, Percent_Identity=31.5508021390374, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI41327764, Length=179, Percent_Identity=32.9608938547486, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI41152114, Length=187, Percent_Identity=31.5508021390374, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI223718708, Length=132, Percent_Identity=34.8484848484849, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI87081735, Length=326, Percent_Identity=61.0429447852761, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1789199, Length=345, Percent_Identity=31.5942028985507, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789375, Length=327, Percent_Identity=32.4159021406728, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788081, Length=300, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788070, Length=325, Percent_Identity=30.4615384615385, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787674, Length=280, Percent_Identity=26.4285714285714, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082198, Length=291, Percent_Identity=25.4295532646048, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI48994888, Length=294, Percent_Identity=26.530612244898, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=40.4761904761905, Blast_Score=255, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6323998, Length=333, Percent_Identity=30.9309309309309, Blast_Score=152, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6319958, Length=295, Percent_Identity=31.1864406779661, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319951, Length=333, Percent_Identity=29.7297297297297, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6322615, Length=259, Percent_Identity=32.4324324324324, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6321052, Length=156, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324694, Length=292, Percent_Identity=25.3424657534247, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646155, Length=168, Percent_Identity=37.5, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24640980, Length=326, Percent_Identity=26.6871165644172, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI45549126, Length=328, Percent_Identity=27.7439024390244, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24646159, Length=164, Percent_Identity=33.5365853658537, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644950, Length=318, Percent_Identity=26.4150943396226, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36151; Mature: 36151

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTKKLGRTGLDISPLCLGCMTYGVPERGPHPWTLREEESRPLIKRALDLGINFFDTANY
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCC
YSDGTSEEIVGRALKDYADRDSIVLATKVYYPQKNQPNAGGLSRKAIFSAIDASLKRLGT
CCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
DYVDLYQIHRWDYATPIEVTLEALHDVVKAGKARYIGASSMFAWQFAKALYTSDLNGWTR
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCHHH
FATMQNHLNLLHREEEREMIPLCADQGIPLLPWSPLARGRLTRDFDAGSARQESDLVGKN
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCC
LYDATVEADRQVVEAVADVARDRGVPRAQVALAWVIQKRGVAAPIIGASKPGHLDDAAAA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
LDLELMPDEIARLEAPYVPHAVVGFQ
EEEEECCHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTKKLGRTGLDISPLCLGCMTYGVPERGPHPWTLREEESRPLIKRALDLGINFFDTANY
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCC
YSDGTSEEIVGRALKDYADRDSIVLATKVYYPQKNQPNAGGLSRKAIFSAIDASLKRLGT
CCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
DYVDLYQIHRWDYATPIEVTLEALHDVVKAGKARYIGASSMFAWQFAKALYTSDLNGWTR
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCHHH
FATMQNHLNLLHREEEREMIPLCADQGIPLLPWSPLARGRLTRDFDAGSARQESDLVGKN
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCC
LYDATVEADRQVVEAVADVARDRGVPRAQVALAWVIQKRGVAAPIIGASKPGHLDDAAAA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
LDLELMPDEIARLEAPYVPHAVVGFQ
EEEEECCHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]