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The map label for this gene is fabZ [H]

Identifier: 218532884

GI number: 218532884

Start: 5354713

End: 5355177

Strand: Reverse

Name: fabZ [H]

Synonym: Mchl_5007

Alternate gene names: 218532884

Gene position: 5355177-5354713 (Counterclockwise)

Preceding gene: 218532885

Following gene: 218532883

Centisome position: 92.68

GC content: 69.89

Gene sequence:

>465_bases
ATGCGGCTCGAATATTTCGAGATGATCGACTCCGTGGTGCGGCTCGACCGCGCCGCCGGCCGCATCGAGGCGCGGGCGCT
CGTGCCTGAGGCGAGCCCGGTCTTCGAGGGGCATTTCCCCGGCCACCCGCTGGTGCCGGGCGTCCTGCTCACTGAGACCA
TGGCACAGGCCTCCGGCTACCTCGTGCTGGCCCATCTCGACTTCGCGCAGATGCCGTTCCTCATGGCCGTGGACAAGGCG
CGCTTCCGCTCCTTCGTCGGTCCGGGGGCTGCCCTCGAGATCACGGCGACCCTGGAGCACGACGGCTCGGGCTACGCGGT
GACGAAGGCCGCCATCCGCCACGAGGGCAAGGCGTTGTGCGACGCGGAGCTGCGGTTCCGCACCATGCCGTTTCCGGCCG
GCCTCGACGCGCCGATGCGCGAACGCGCCCGGAAGATCGGCCTTTTGGATGGAGCCCAGCCGTGA

Upstream 100 bases:

>100_bases
CAGTACTTCGTGCTGAAAAACCTCTGCGCACGCATTGACGCTCTGGTCGCCGAAAAGGCCGCCAAGGCCTGATCCGTCGG
GCTTCAGGGATTCACGCGCG

Downstream 100 bases:

>100_bases
GTCGTCCGCAGGCCCGCGACGTCCAGGCTCGCGACGTCGTCGTCACCGGGATCGGCCTCGTCTCCTGCGCGGGCGAGGGG
ATCGAGACGCACCTGAACGC

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MRLEYFEMIDSVVRLDRAAGRIEARALVPEASPVFEGHFPGHPLVPGVLLTETMAQASGYLVLAHLDFAQMPFLMAVDKA
RFRSFVGPGAALEITATLEHDGSGYAVTKAAIRHEGKALCDAELRFRTMPFPAGLDAPMRERARKIGLLDGAQP

Sequences:

>Translated_154_residues
MRLEYFEMIDSVVRLDRAAGRIEARALVPEASPVFEGHFPGHPLVPGVLLTETMAQASGYLVLAHLDFAQMPFLMAVDKA
RFRSFVGPGAALEITATLEHDGSGYAVTKAAIRHEGKALCDAELRFRTMPFPAGLDAPMRERARKIGLLDGAQP
>Mature_154_residues
MRLEYFEMIDSVVRLDRAAGRIEARALVPEASPVFEGHFPGHPLVPGVLLTETMAQASGYLVLAHLDFAQMPFLMAVDKA
RFRSFVGPGAALEITATLEHDGSGYAVTKAAIRHEGKALCDAELRFRTMPFPAGLDAPMRERARKIGLLDGAQP

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=123, Percent_Identity=35.7723577235772, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16776; Mature: 16776

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLEYFEMIDSVVRLDRAAGRIEARALVPEASPVFEGHFPGHPLVPGVLLTETMAQASGY
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCE
LVLAHLDFAQMPFLMAVDKARFRSFVGPGAALEITATLEHDGSGYAVTKAAIRHEGKALC
EEEEECCHHHCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEHHHHHHHCCCCEE
DAELRFRTMPFPAGLDAPMRERARKIGLLDGAQP
CCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRLEYFEMIDSVVRLDRAAGRIEARALVPEASPVFEGHFPGHPLVPGVLLTETMAQASGY
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCE
LVLAHLDFAQMPFLMAVDKARFRSFVGPGAALEITATLEHDGSGYAVTKAAIRHEGKALC
EEEEECCHHHCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEHHHHHHHCCCCEE
DAELRFRTMPFPAGLDAPMRERARKIGLLDGAQP
CCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA