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The map label for this gene is yxnA [H]

Identifier: 218532847

GI number: 218532847

Start: 5309829

End: 5310863

Strand: Reverse

Name: yxnA [H]

Synonym: Mchl_4970

Alternate gene names: 218532847

Gene position: 5310863-5309829 (Counterclockwise)

Preceding gene: 218532848

Following gene: 218532846

Centisome position: 91.92

GC content: 72.95

Gene sequence:

>1035_bases
TTGGCAGGGCAGGGACGAAAAGGTGCTGCGCGGGTTGCCGTGGTCACGGGCGGAAGCGCCGGGATCGGTCTCGCCACGGC
CCAGCTTCTCGCGCAACGCGGCTGGTCGGTGGCGATCCTGGCACGCGGTGCCGAGCGTCTCGCCGAGGCCGAGGCGCTGC
TCGCCCGCGAGGGTGGGCGCGTGCTGGCGATCCCGGCCGATGTGGCCGACGCCGCGGTGGTCGAGGCGGCGGCCGACCGG
ATCGAGCGGGAGCTCGGGCCGATCCGGGCCTGGATCAACAACGCCATGACGACGATCGTCAGCCCGGCCGACCAGGTCAC
CCCGGAGGAGTACCGCACCGTCACCGAGGCGACCTATCTCGGCACCGTCCACGGCACGCTGGCGGCCCTGCGCCGCATGA
ATCCGCGCGACCGCGGCGTGATCGTGCAGGTCTCCTCCGGGCTGGCGATCCGCGCGGCTCCGCTCCAGGCGCCCTATTGC
GCGGCGAAGTTCGCGATCAGCGGCTTCACCGACTCGCTGCGCGCCGAACTGATCCACGAGAACAGCAAGATCGCGCTCAG
CGTGGTCTACCTGCCGGCGGTCAACACACCGCAATTCGGCTGGACCCGCACCCGGACCGGCCACGGACAGCGCGCCCCCG
ATCCCGTCTTCGATCCGCGCCTGTGCGCGGAGGCGATCCACCACGCGGCCGAGCGGCCGACCCGCGAGGTCTGGGTCGGA
CGGACCTCGGTGCTGATGGCGGCGGCCCAGGCCCTCCTGCCGTCCTACGCCGACCGCAAGGCAGCAGAGAGTTGGGACGA
CATGGTGGAGGACGAGGCGGTCCCGGATCGGCGTGGCAACCTCGACGCACCGGCGCCGGGCCCGGCGCGCATCGATGGCG
CCATGAGTGAGCGTGCCAAGACGACCCGCTCCGAGTTCTGGACCAGCCGGGAGCGCGATGCCCTCGTGCTCGGTGCCGTG
GGCGCCGCCCTCCTCGGAACCGCCCTGGCGGCGCGCGCTCTTCGCCGGCCGCTGCGTCTGCTCGGGCGGCTCTGA

Upstream 100 bases:

>100_bases
ATCCAACGGTCCAGGCTCGCATCGTCGCAGCGTCGTCCGCGCCGCAACTCCGCCCGCACAGCGCGCATTGACGGGCAGGA
TGAGCGCAGGAGGATGCGGT

Downstream 100 bases:

>100_bases
GCGAAAGCGCATCCGACGAAGTGATCACCGGTTCGTCGAGAGAATGCACGTCAAAACAAAGAGCTAGAGCGCCGGGCTGA
TACAGTCAGGTCGGATACGG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MAGQGRKGAARVAVVTGGSAGIGLATAQLLAQRGWSVAILARGAERLAEAEALLAREGGRVLAIPADVADAAVVEAAADR
IERELGPIRAWINNAMTTIVSPADQVTPEEYRTVTEATYLGTVHGTLAALRRMNPRDRGVIVQVSSGLAIRAAPLQAPYC
AAKFAISGFTDSLRAELIHENSKIALSVVYLPAVNTPQFGWTRTRTGHGQRAPDPVFDPRLCAEAIHHAAERPTREVWVG
RTSVLMAAAQALLPSYADRKAAESWDDMVEDEAVPDRRGNLDAPAPGPARIDGAMSERAKTTRSEFWTSRERDALVLGAV
GAALLGTALAARALRRPLRLLGRL

Sequences:

>Translated_344_residues
MAGQGRKGAARVAVVTGGSAGIGLATAQLLAQRGWSVAILARGAERLAEAEALLAREGGRVLAIPADVADAAVVEAAADR
IERELGPIRAWINNAMTTIVSPADQVTPEEYRTVTEATYLGTVHGTLAALRRMNPRDRGVIVQVSSGLAIRAAPLQAPYC
AAKFAISGFTDSLRAELIHENSKIALSVVYLPAVNTPQFGWTRTRTGHGQRAPDPVFDPRLCAEAIHHAAERPTREVWVG
RTSVLMAAAQALLPSYADRKAAESWDDMVEDEAVPDRRGNLDAPAPGPARIDGAMSERAKTTRSEFWTSRERDALVLGAV
GAALLGTALAARALRRPLRLLGRL
>Mature_343_residues
AGQGRKGAARVAVVTGGSAGIGLATAQLLAQRGWSVAILARGAERLAEAEALLAREGGRVLAIPADVADAAVVEAAADRI
ERELGPIRAWINNAMTTIVSPADQVTPEEYRTVTEATYLGTVHGTLAALRRMNPRDRGVIVQVSSGLAIRAAPLQAPYCA
AKFAISGFTDSLRAELIHENSKIALSVVYLPAVNTPQFGWTRTRTGHGQRAPDPVFDPRLCAEAIHHAAERPTREVWVGR
TSVLMAAAQALLPSYADRKAAESWDDMVEDEAVPDRRGNLDAPAPGPARIDGAMSERAKTTRSEFWTSRERDALVLGAVG
AALLGTALAARALRRPLRLLGRL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=170, Percent_Identity=35.8823529411765, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4503817, Length=191, Percent_Identity=29.8429319371728, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI40254992, Length=179, Percent_Identity=31.8435754189944, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI4557649, Length=197, Percent_Identity=28.4263959390863, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40807363, Length=255, Percent_Identity=26.2745098039216, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI10190704, Length=175, Percent_Identity=29.7142857142857, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=178, Percent_Identity=32.5842696629214, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI20149619, Length=184, Percent_Identity=29.3478260869565, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI150247226, Length=182, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI7657478, Length=181, Percent_Identity=28.1767955801105, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI31542939, Length=190, Percent_Identity=30.5263157894737, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI2367175, Length=172, Percent_Identity=33.1395348837209, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790717, Length=176, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787335, Length=167, Percent_Identity=31.1377245508982, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71997402, Length=209, Percent_Identity=33.4928229665072, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=259, Percent_Identity=26.6409266409266, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=30.078125, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=167, Percent_Identity=28.7425149700599, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=176, Percent_Identity=30.1136363636364, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=25.9541984732824, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=217, Percent_Identity=33.1797235023041, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356301, Length=309, Percent_Identity=27.831715210356, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=30, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571387, Length=182, Percent_Identity=32.4175824175824, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641232, Length=195, Percent_Identity=31.7948717948718, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI281364892, Length=170, Percent_Identity=30, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364494, Length=201, Percent_Identity=30.8457711442786, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36565; Mature: 36434

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQGRKGAARVAVVTGGSAGIGLATAQLLAQRGWSVAILARGAERLAEAEALLAREGGR
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCE
VLAIPADVADAAVVEAAADRIERELGPIRAWINNAMTTIVSPADQVTPEEYRTVTEATYL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHH
GTVHGTLAALRRMNPRDRGVIVQVSSGLAIRAAPLQAPYCAAKFAISGFTDSLRAELIHE
HHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHC
NSKIALSVVYLPAVNTPQFGWTRTRTGHGQRAPDPVFDPRLCAEAIHHAAERPTREVWVG
CCCEEEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCC
RTSVLMAAAQALLPSYADRKAAESWDDMVEDEAVPDRRGNLDAPAPGPARIDGAMSERAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TTRSEFWTSRERDALVLGAVGAALLGTALAARALRRPLRLLGRL
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGQGRKGAARVAVVTGGSAGIGLATAQLLAQRGWSVAILARGAERLAEAEALLAREGGR
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCE
VLAIPADVADAAVVEAAADRIERELGPIRAWINNAMTTIVSPADQVTPEEYRTVTEATYL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHH
GTVHGTLAALRRMNPRDRGVIVQVSSGLAIRAAPLQAPYCAAKFAISGFTDSLRAELIHE
HHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHC
NSKIALSVVYLPAVNTPQFGWTRTRTGHGQRAPDPVFDPRLCAEAIHHAAERPTREVWVG
CCCEEEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCC
RTSVLMAAAQALLPSYADRKAAESWDDMVEDEAVPDRRGNLDAPAPGPARIDGAMSERAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TTRSEFWTSRERDALVLGAVGAALLGTALAARALRRPLRLLGRL
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]