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The map label for this gene is bdlA [H]

Identifier: 218532845

GI number: 218532845

Start: 5306890

End: 5308350

Strand: Reverse

Name: bdlA [H]

Synonym: Mchl_4968

Alternate gene names: 218532845

Gene position: 5308350-5306890 (Counterclockwise)

Preceding gene: 218532846

Following gene: 218532844

Centisome position: 91.87

GC content: 67.69

Gene sequence:

>1461_bases
ATGTTCCGTAAGCCCAAGCAAAGTGACGCCCAAGCGAAGCTCGATGCACTCGATCGATCGCTCGCGACCATTGAGTTCGC
GATGGATGGGACGGTTCTCGACGCGAACCGGAACTTTCTCGACGCGATCGGCTACGAGCTCGACGAGATCAAGGGCCGGC
ATCACCGCATCTTTGTCGAGGCCGCCTATGCCGAGAGCGCCGATTATCGCGCCTTCTGGGAGACGCTGCGCGGCGGCAAG
TACGCCTCGGGCGAGTTCCCCCGTCTCGGCAAGTCCGGCCGCAAGATCTGGCTGGAAGCGACCTACAACCCGGTGCTCGG
GGCGGATGGCAAGCCGGAGCGGGTGATGAAGTTCGCGACCGACATCACCGCCAAGAAGAACGAGACGAGCCGACTCCTGA
CGATGATCGACGGCATGCCCGTCGCCGTCATGACGGTGGACCCGAAGGACGAGTTCAAGATCAACTATCTGAACAAGACC
TCGGTGACGACGCTCTCCACCATCGAGGAGCATCTGCCGATCAAGGTCTCGGAGATGATGGGCCGCTCCTTCGACGTCTT
CCACAAGCACCCGCAGCATCAGCGGACGATGCTGGCCGACAGCAGCCGCCTGCCGCACCGGGCCAAGATCCGGGTCGGCC
CCGAGACCCTCGATCTGCGCGTCTCGGCGATCCACGGGCCCGAGGGCGAGTATGTCGGCCCGATGGTGACGTGGTCGGTG
ATCACCGCGCAGGTTCAGATGTCGGCGGACGTCTCGCGGGTGGTCGAGGCGGTGCGGTCGGCGGTGGAGCGGATGGGGTC
CTCGGCGGAGGAGCTGTCGCGCTCGGCCGAGGATGCCCGGCAGCGCGCGGCCTCGGTGGCGGCGGGCTCGGCGCAGATGA
CGGCGTCGATCCAAGAGATTTCGGGGCAGGTCGGCAGCGTGTCCGAGCGCGCCCAGCGGATCGCGGCCCAGGCCGAAACG
ACAGATCTGACGGTGCGCCAGCTCGCCGAGAACGCGCGCAAGGTCGATGCGGTGGTGGCGATGATCCGCTCGATCGCCGA
TCAGACCAACCTGCTCGCCCTCAACGCCACCATCGAAGCGGCCCGCGCGGGCGCGGCCGGCCGCGGCTTCGCCGTGGTCG
CCGCCGAAGTGAAGGCGCTGGCCGAGCAGACGGCGAAAGCGACCGGCGAGATTTCCGGACAGATCGCCGCGATCCAGAGC
GCCACCGGCGAGGCGGTCGAGGCCATCGGCACGATCACCGCGGCGGTGACGGACCTCTCGGGGCTCACCCTCGCCATGGC
GAGTGCGGTCGAGGAGCAGGCGGCCTCGACGCACGAGATGTCCGGCAACATCGTCGGCGTGTCCTCGGCGGCGGACGCCA
CCGGCAGCCATGTCGACTCGGTCCGCACCATCGCCGAGGATCTCGCGACGCATTCCGCCGGGCTGGGCGCCAGCGTCGAG
AAGTTCCTCAAGGCGAGCTGA

Upstream 100 bases:

>100_bases
AAGATATCGAGCGAAATCGCCGAGATCCGCCCTCGATCAATGACGACATCGCTCTGGCGACGTGGCTGCCGGAGAAAGAT
TGCGTCACGGGGGTTCTGTG

Downstream 100 bases:

>100_bases
GATCGGGACGCGGACGGGAAGAACTGCGCAAGGCCGATGTGCCGCATGTCACGACAATCGGTCGTGCCATGCAACCGGGC
GCCGCCGAAGGGCTTATCAC

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MFRKPKQSDAQAKLDALDRSLATIEFAMDGTVLDANRNFLDAIGYELDEIKGRHHRIFVEAAYAESADYRAFWETLRGGK
YASGEFPRLGKSGRKIWLEATYNPVLGADGKPERVMKFATDITAKKNETSRLLTMIDGMPVAVMTVDPKDEFKINYLNKT
SVTTLSTIEEHLPIKVSEMMGRSFDVFHKHPQHQRTMLADSSRLPHRAKIRVGPETLDLRVSAIHGPEGEYVGPMVTWSV
ITAQVQMSADVSRVVEAVRSAVERMGSSAEELSRSAEDARQRAASVAAGSAQMTASIQEISGQVGSVSERAQRIAAQAET
TDLTVRQLAENARKVDAVVAMIRSIADQTNLLALNATIEAARAGAAGRGFAVVAAEVKALAEQTAKATGEISGQIAAIQS
ATGEAVEAIGTITAAVTDLSGLTLAMASAVEEQAASTHEMSGNIVGVSSAADATGSHVDSVRTIAEDLATHSAGLGASVE
KFLKAS

Sequences:

>Translated_486_residues
MFRKPKQSDAQAKLDALDRSLATIEFAMDGTVLDANRNFLDAIGYELDEIKGRHHRIFVEAAYAESADYRAFWETLRGGK
YASGEFPRLGKSGRKIWLEATYNPVLGADGKPERVMKFATDITAKKNETSRLLTMIDGMPVAVMTVDPKDEFKINYLNKT
SVTTLSTIEEHLPIKVSEMMGRSFDVFHKHPQHQRTMLADSSRLPHRAKIRVGPETLDLRVSAIHGPEGEYVGPMVTWSV
ITAQVQMSADVSRVVEAVRSAVERMGSSAEELSRSAEDARQRAASVAAGSAQMTASIQEISGQVGSVSERAQRIAAQAET
TDLTVRQLAENARKVDAVVAMIRSIADQTNLLALNATIEAARAGAAGRGFAVVAAEVKALAEQTAKATGEISGQIAAIQS
ATGEAVEAIGTITAAVTDLSGLTLAMASAVEEQAASTHEMSGNIVGVSSAADATGSHVDSVRTIAEDLATHSAGLGASVE
KFLKAS
>Mature_486_residues
MFRKPKQSDAQAKLDALDRSLATIEFAMDGTVLDANRNFLDAIGYELDEIKGRHHRIFVEAAYAESADYRAFWETLRGGK
YASGEFPRLGKSGRKIWLEATYNPVLGADGKPERVMKFATDITAKKNETSRLLTMIDGMPVAVMTVDPKDEFKINYLNKT
SVTTLSTIEEHLPIKVSEMMGRSFDVFHKHPQHQRTMLADSSRLPHRAKIRVGPETLDLRVSAIHGPEGEYVGPMVTWSV
ITAQVQMSADVSRVVEAVRSAVERMGSSAEELSRSAEDARQRAASVAAGSAQMTASIQEISGQVGSVSERAQRIAAQAET
TDLTVRQLAENARKVDAVVAMIRSIADQTNLLALNATIEAARAGAAGRGFAVVAAEVKALAEQTAKATGEISGQIAAIQS
ATGEAVEAIGTITAAVTDLSGLTLAMASAVEEQAASTHEMSGNIVGVSSAADATGSHVDSVRTIAEDLATHSAGLGASVE
KFLKAS

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=209, Percent_Identity=33.0143540669856, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788194, Length=249, Percent_Identity=30.5220883534137, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787690, Length=258, Percent_Identity=30.2325581395349, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1789453, Length=218, Percent_Identity=33.0275229357798, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788195, Length=198, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 51815; Mature: 51815

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRKPKQSDAQAKLDALDRSLATIEFAMDGTVLDANRNFLDAIGYELDEIKGRHHRIFVE
CCCCCCCCHHHHHHHHHHHHHHEEEEEECCEEEECCCCHHHHHCCCHHHHCCCCEEEEEE
AAYAESADYRAFWETLRGGKYASGEFPRLGKSGRKIWLEATYNPVLGADGKPERVMKFAT
EECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHH
DITAKKNETSRLLTMIDGMPVAVMTVDPKDEFKINYLNKTSVTTLSTIEEHLPIKVSEMM
HHHCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCEEHHHHC
GRSFDVFHKHPQHQRTMLADSSRLPHRAKIRVGPETLDLRVSAIHGPEGEYVGPMVTWSV
CCCCHHHHCCCCHHHHHHHCCCCCCCCEEEEECCCEEEEEEEEEECCCCCCCCCHHEEHH
ITAQVQMSADVSRVVEAVRSAVERMGSSAEELSRSAEDARQRAASVAAGSAQMTASIQEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SGQVGSVSERAQRIAAQAETTDLTVRQLAENARKVDAVVAMIRSIADQTNLLALNATIEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHH
ARAGAAGRGFAVVAAEVKALAEQTAKATGEISGQIAAIQSATGEAVEAIGTITAAVTDLS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHC
GLTLAMASAVEEQAASTHEMSGNIVGVSSAADATGSHVDSVRTIAEDLATHSAGLGASVE
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
KFLKAS
HHHCCC
>Mature Secondary Structure
MFRKPKQSDAQAKLDALDRSLATIEFAMDGTVLDANRNFLDAIGYELDEIKGRHHRIFVE
CCCCCCCCHHHHHHHHHHHHHHEEEEEECCEEEECCCCHHHHHCCCHHHHCCCCEEEEEE
AAYAESADYRAFWETLRGGKYASGEFPRLGKSGRKIWLEATYNPVLGADGKPERVMKFAT
EECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHH
DITAKKNETSRLLTMIDGMPVAVMTVDPKDEFKINYLNKTSVTTLSTIEEHLPIKVSEMM
HHHCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCEEHHHHC
GRSFDVFHKHPQHQRTMLADSSRLPHRAKIRVGPETLDLRVSAIHGPEGEYVGPMVTWSV
CCCCHHHHCCCCHHHHHHHCCCCCCCCEEEEECCCEEEEEEEEEECCCCCCCCCHHEEHH
ITAQVQMSADVSRVVEAVRSAVERMGSSAEELSRSAEDARQRAASVAAGSAQMTASIQEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SGQVGSVSERAQRIAAQAETTDLTVRQLAENARKVDAVVAMIRSIADQTNLLALNATIEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHH
ARAGAAGRGFAVVAAEVKALAEQTAKATGEISGQIAAIQSATGEAVEAIGTITAAVTDLS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHC
GLTLAMASAVEEQAASTHEMSGNIVGVSSAADATGSHVDSVRTIAEDLATHSAGLGASVE
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
KFLKAS
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]